Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortalityObservational Study Published on 2022-06-012022-10-05 Journal: Intensive care medicine [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI acute respiratory distress adjusted Adjusted analysis affected association Blood CMV coronavirus disease COVID-19 Cox proportional hazard Critically ill Critically ill patient cytomegalovirus Cytomegalovirus reactivation Effect evaluated Hospital mortality ICU ICU admission ICU patient incidence increased risk intensive care Invasive mechanical ventilation large cohort Mechanical mechanical ventilation Mortality Occurrence outcome Patient Physiology Platelet Quantitative regression models risk factor SARS-COV-2 infection score screened secondary bacterial infection Sepsis severity syndrome worsening [DOI] 10.1007/s00134-022-06716-y PMC 바로가기 [Article Type] Observational Study
Prognosis of patients with acute respiratory failure due to the SARS-CoV-2 501Y.V2 variant: a multicenter retrospective matched cohort studySARS-CoV-2 501Y.V2 변이로 인한 급성 호흡 부전 환자의 예후: 다기관 후향적 일치 코호트 연구Multicenter Study Published on 2022-05-242022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] 28-day mortality 501Y.V2 Acute respiratory failure acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ARF Care Chronic kidney disease cohort study confounding variable confounding variables consecutive patient coronavirus enrolled evaluated extracorporeal membrane oxygenation Health Health care Health care system hospital Hospital mortality Hospitalized hypertension incidence intensive care intensive care unit Invasive mechanical ventilation island Kidney disease less Mortality multicenter Patient Prognosis prognosis of patient remained Respiratory failure retrospective SARS-CoV-2 saturated severe acute respiratory syndrome Coronavirus supported the SARS-CoV-2 university variant venovenous extracorporeal membrane oxygenation were infected [DOI] 10.1038/s41598-022-12767-4 PMC 바로가기 [Article Type] Multicenter Study
Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses코로나19 입원 환자를 위한 렘데시비르 및 기타 3가지 약물: WHO 연대 무작위 시험의 최종 결과 및 업데이트된 메타 분석Meta-Analysis Published on 2022-05-212022-09-11 Journal: Lancet (London, England) [Category] 신약개발, 임상, 치료제, [키워드] 1:1 allocation Analysis antiviral drugs assigned average both groups Characteristics Compliance controls country COVID-19 COVID-19 diagnosis database death died discharge discharged disease severity drug drugs eligible patient Endpoint enrolled exclusion Final futility hospital Hospital mortality hospitalised hospitalised patient Hospitalised patients Hydroxychloroquine in both groups in-hospital mortality Inpatient Inpatients interferon ISRCTN Kaplan-Meier Local Lopinavir meta-analyses Meta-analysis Mortality mortality analysis mortality rate ratio no significant effect occurred Open-label outcome oxygen participant Patient patients patients with COVID-19 Placebo placebos primary endpoint progressed progression proportion randomisation Randomised trial Randomly rate ratio receive recruited regions Registered Remdesivir reported secondary Secondary endpoints solidarity Solidarity trial Standard of care study drug the WHO treatment period Trial Ventilated Ventilation were given WHO [DOI] 10.1016/S0140-6736(22)00519-0 PMC 바로가기 [Article Type] Meta-Analysis
A case-control, multicentre study of consecutive patients with COVID-19 and acute (myo)pericarditis: incidence, risk factors, clinical characteristics and outcomesCOVID-19 및 급성(심근)심낭염 환자에 대한 사례 대조, 다기관 연구: 발병률, 위험 요인, 임상적 특성 및 결과Multicenter Study Published on 2022-05-012022-09-11 Journal: Emergency medicine journal : EMJ [Category] MERS, 바이오마커, [키워드] adjusted Brain brain natriuretic peptide Case-control changes chest pain Clinical characteristics consecutive patient control group COVID-19 COVID-19 case COVID-19 patient drugs dysfunction ECG echocardiographic echocardiography Hospital mortality In-hospital in-hospital mortality incidence Inclusion intensive care less multicentre N-terminal NT-proBNP outcome Patient patients with COVID-19 peptide performed Population prohormone retrospective retrospective review Risk factors Spanish symptomatic Treatment vasoactive drug vasoactive drugs ventricular dysfunction with COVID-19 [DOI] 10.1136/emermed-2020-210977 PMC 바로가기 [Article Type] Multicenter Study
Prognostic value of copeptin and mid-regional proadrenomedullin in COVID-19-hospitalized patientsCOVID-19 입원 환자에서 코펩틴 및 중부 프로아드레노메둘린의 예후 가치Article Published on 2022-05-012022-09-11 Journal: European Journal of Clinical Investigation [Category] MERS, 바이오마커, [키워드] Acute kidney injury Admission AUROC Biomarkers Care complications copeptin coronavirus disease Coronavirus disease 2019 COVID-19 database death Diagnosis eligible endothelial function expressed hazard ratio help Hospital mortality identify In-hospital in-hospital complication in-hospital complications in-hospital mortality intensive care intensive care unit interquartile range marker median mid-regional proadrenomedullin Mortality MR-proADM non-survivor Non-survivors outcome outcomes Patient patients hospitalized Pneumonia predict predicted predictive power primary endpoint Prognosis Receiver operator characteristic risk stratification secondary endpoint Secondary endpoints Sepsis Septic shock Stress survivor was increased were assessed with COVID-19 [DOI] 10.1111/eci.13753 PMC 바로가기 [Article Type] Article
Aspartate transferase-to-platelet ratio index-plus: A new simplified model for predicting the risk of mortality among patients with COVID-19Aspartate transferase-to-platelet ratio index-plus: COVID-19 환자의 사망 위험을 예측하기 위한 새로운 단순화 모델Multicenter Study Published on 2022-04-282022-09-11 Journal: World journal of gastroenterology [Category] 바이오마커, [키워드] Admission age all consecutive adult patients All-cause in-hospital mortality an area analyses analyzed aspartate Aspartate transferase Aspartate transferase-to-platelet ratio index association Biomarker category clinically conducted confounders coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality COVID-19 patients develop died ferritin Hospital mortality Hospital stay In-hospital in-hospital mortality include inclusion criteria independent independent of intensive care intensive care unit liver Liver injury Logistic regression Logistic regression analyses lung male median age medical record medical records Mortality multicenter cohort study on admission Patient patient cohort patients with COVID-19 performance Platelet Platelets Predictive predictor predictors presenting regression analysis retrieved retrospective risk SARS-CoV-2 Serum ferritin significantly Spectrum syndrome university [DOI] 10.3748/wjg.v28.i16.1671 PMC 바로가기 [Article Type] Multicenter Study
Risk factors and early prediction of clinical deterioration and mortality in adult COVID-19 inpatients: an Australian tertiary hospital experienceArticle Published on 2022-04-012023-07-07 Journal: Internal medicine journal [Category] COVID19(2023년), [키워드] blood chemical analysis Clinical deterioration COVID-19 haematologic test Hospital mortality SARS-CoV-2 [DOI] 10.1111/imj.15631 PMC 바로가기
Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study미국의 오미크론, 델타 및 알파 SARS-CoV-2 변이체의 covid-19에 대한 mRNA 백신의 임상 중증도 및 효과: 전향적 관찰 연구Observational Study Published on 2022-03-092022-09-11 Journal: The BMJ [Category] SARS, 변종, 임상, [키워드] 95% confidence interval adjusted Alpha Alpha variant calculated case-control study circulating clinical Clinical severity controls delta variant disease severity dose effective Effectiveness group Health Organization hospital Hospital admission Hospital admissions Hospital mortality in-hospital mortality less Lineage morbidity and mortality Mortality mRNA vaccine mRNA vaccines Odds ratio omicron Omicron variant Omicron variants outcome Patient patients predominant Prevent progression prospective observational study provided required SARS-CoV-2 variant Sequencing severe disease severity significantly lower test negative The United States the WHO United States vaccine dose variant variants WHO Clinical Progression Scale whole genome Whole genome sequencing World Health Organization [DOI] 10.1136/bmj-2021-069761 PMC 바로가기 [Article Type] Observational Study
Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective StudyCOVID-19로 입원한 환자의 낮은 생존율에 대한 위험 요인으로 입원 시 낮은 비타민 D 상태: 이탈리아 후향적 연구Article Published on 2022-03-012022-09-11 Journal: Journal of the American Nutrition Association [Category] MERS, SARS, 바이오마커, [키워드] 25-hydroxyvitamin D 95% confidence interval Admission Alpha Analysis association available data best Biomarker blood cell C-reactive protein characteristic Clinical course Coagulation Cohort conducted consecutive patient count COVID-19 cytokine Cytokine storm D-dimer different time point evaluate exhibited Factor ferritin fibrinogen High-sensitivity C-reactive protein hospital Hospital mortality Hospitalization hospitalized patient hospitalized patients hsCRP hypovitaminosis Hypovitaminosis D IL-6 in-hospital mortality incidence independent risk factor Inflammation Inflammatory inflammatory markers institution interleukin interleukin 6 Italian logistic regression model lymphocyte marker median Mortality Multivariate analysis Necrosis neutrophil NLR non-survivor Non-survivors Odds ratio Patient PCT performed Poor poor prognosis Predictive preliminary findings Prevalence procalcitonin receiver operating characteristic Retrospective study risk SARS-CoV-2 SARS-COV-2 infection Sepsis serum serum 25-hydroxyvitamin D severity of COVID-19 significantly significantly higher status subsequent survivor the disease TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha two groups Vitamin Vitamin D Vitamin D status WBC WBC count White blood cell with COVID-19 [DOI] 10.1080/07315724.2021.1877580 PMC 바로가기 [Article Type] Article
Circulating miR-320b and miR-483-5p levels are associated with COVID-19 in-hospital mortality순환하는 miR-320b 및 miR-483-5p 수준은 COVID-19 병원 내 사망률과 관련이 있습니다Comparative Study Published on 2022-03-012022-09-11 Journal: Mechanisms of ageing and development [Category] MERS, 바이오마커, 진단, [키워드] adjusted Analysis analyzed Biomarker circulating circulating miRNA circulating miRNAs Cohort confounders COVID-19 COVID-19 patient Cox regression models Deceased deregulated downregulated expression levels highest Hospital mortality IMPROVE In-hospital in-hospital mortality increased risk independent invasive Kaplan-Meier management microRNA MiR-320b MiR-483-5p miRNA miRNAs molecular mortality risk Older older patients Patient Patient management Physicians qRT-PCR risk of COVID-19 RNA-Seq selected Serum level serum levels serum sample serum samples significantly Stratification survived Survivors upregulated validation cohort with COVID-19 [DOI] 10.1016/j.mad.2022.111636 PMC 바로가기 [Article Type] Comparative Study