Mutational Asymmetries in the SARS-CoV-2 Genome May Lead to Increased Hydrophobicity of Virus ProteinsSARS-CoV-2 게놈의 돌연변이 비대칭으로 인해 바이러스 단백질의 소수성이 증가할 수 있음Article Published on 2021-05-272022-09-10 Journal: Genes [Category] SARS, 변종, [키워드] Amino acid amino acid hydrophobicity amino acids analyzed apolipoprotein B mRNA editing enzyme (APOBEC) arising asymmetry biochemical cellular membranes character circulating codon Codons coronavirus COVID-19 COVID-19 pandemic COVID-19 therapy data set distribution eight Evolution explained favor feature focus fusion G>U transversion Genetic variation genomic Genotype genotypes GISAID database Host hydrophilic hydrophobic amino acid hydrophobicity Increased lead majority mutability Mutation mutations protein–protein interactions Proteins S-protein SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 lineage single-nucleotide Substitution substitutions the SARS-CoV-2 therapy Treatment variants variants of interest variations Viral virion assembly virus virus genome [DOI] 10.3390/genes12060826 PMC 바로가기 [Article Type] Article
COVID-19: insights into virus–receptor interactionsPerspective Published on 2021-04-102022-10-30 Journal: Molecular Biomedicine [Category] COVID-19, [키워드] ACE2 ACE2 receptor acute respiratory syndrome Adsorption Analysis approach assessment biological interaction conformational change conformational changes coronavirus coronavirus strain COVID-19 disease Factor glycosylation host cell hydrophobicity Interaction interactions kinetic outbreak probe SARS-CoV-2 sequence similarity thermodynamic Thermodynamics transmissibility of SARS-CoV-2 Virus-cell interactions [DOI] 10.1186/s43556-021-00033-4 PMC 바로가기 [Article Type] Perspective
Why are ACE2 binding coronavirus strains SARS-CoV/SARS-CoV-2 wild and NL63 mild?ACE2 결합 코로나바이러스 균주 SARS-CoV/SARS-CoV-2가 야생이고 NL63이 약한 이유는 무엇입니까?Article Published on 2021-04-012022-09-11 Journal: Proteins [Category] SARS, 변종, 치료제, [키워드] ACE2 ACE2 binding angiotensin Angiotensin-converting enzyme antiviral drug antiviral drugs binding binding site Cluster conserved coronavirus coronavirus spike protein coronavirus strain coronavirus strains Coronaviruses COVID-19 COVID-19 pandemic drugs effort enzyme Epidemics etiology feature flexibility help human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 hydrophobic hydrophobicity identify indicated Interaction involved MERS mutational analysis NL63 Point mutation Protein Research researcher residue residues responsible reveal SARS SARS-CoV SARS-CoV-2 virus severity similarities similarity Spike protein Spike proteins strain Strains surrounding hydrophobicity. the spike protein therapeutic virus Virus-host interactions [DOI] 10.1002/prot.26024 PMC 바로가기 [Article Type] Article
Could Nanotheranostics be the Answer to the Coronavirus Crisis?Review Published on 2021-03-242022-10-31 Journal: Global Challenges [Category] COVID-19, [키워드] anti‐coronavirus Antiviral appraisals Bacterial China clinical trials coronavirus Coronaviruses COVID‐19 detect diagnose electrical electrospun facemasks Endosomal acidification fiber Hospital admission hydrophobicity inhibiting N95 respirators nanodiagnostics Nanoparticles offered pandemic preventing infection provide response Safety assessment Staphylococcus aureus treat viral replication [DOI] 10.1002/gch2.202000112 PMC 바로가기 [Article Type] Review
Screening and Molecular Modeling Evaluation of Food Peptides to Inhibit Key Targets of COVID-19 VirusCOVID-19 바이러스의 주요 표적을 억제하기 위한 식품 펩타이드의 스크리닝 및 분자 모델링 평가Article Published on 2021-02-222022-09-10 Journal: Biomolecules [Category] MERS, 신약개발, [키워드] (RdRp) ACE2 Acidic activity Amino acid amino acids angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Antiviral aromatic amino acid binding COVID-19 COVID-19 virus drugs FIVE food food peptides functional head hydrophilic hydrophobicity inhibit Interaction M pro middle modeling molecular docking molecular dynamic simulation nine peptide peptides protease RdRP reported RNA polymerase RNA-dependent RNA polymerase Screening side Simulation tail target targets therapeutic effect variety virus with COVID-19 [DOI] 10.3390/biom11020330 PMC 바로가기 [Article Type] Article
Domains and Functions of Spike Protein in SARS-Cov-2 in the Context of Vaccine Design백신 설계의 맥락에서 SARS-Cov-2에서 스파이크 단백질의 도메인 및 기능Review Published on 2021-01-142022-09-10 Journal: Viruses [Category] 변종, [키워드] approach BNT162b2 build candidate Cell cell entry cleavage cleaved Context COVID-19 dissect domain ENhance events foundation function human ACE2 receptor human cell hydrophobicity Infection integration interact isoelectric point membrane fusion Moderna mRNA mRNA-1273 vaccine Pfizer Pfizer/BioNTech prefusion produced protein structure Receptor binding S-2P S1 and S2 SARS-2-S SARS-CoV-2 spike Spike protein subsequent subunits the spike protein translated Transmission Vaccine vaccine candidates Vaccine development variety Viral viral entry Viral variants [DOI] 10.3390/v13010109 PMC 바로가기 [Article Type] Review
Scalable in-hospital decontamination of N95 filtering face-piece respirator with a peracetic acid room disinfection system과초산실 소독 시스템을 갖춘 N95 필터링 안면 마스크의 병원 내 오염 제거 확장 가능Original Article Published on 2020-10-122022-09-10 Journal: Infection Control and Hospital Epidemiology [Category] MERS, SARS, 치료기술, [키워드] adverse effect adverse effects change conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic decontamination defined detectable Disinfection effective Efficiency Elasticity evaluate filtration for disinfection generate HCWs healthcare worker Healthcare workers help hydrogen hydrogen peroxide hydrophobicity In-hospital inoculated log Mask MS2 N95 respirator N95 respirators novel pandemic peracetic acid Personal protective equipment Pragmatic provide reductions in Respirator respirators Safe spore STRAP treated Treatment were assessed [DOI] 10.1017/ice.2020.1257 PMC 바로가기 [Article Type] Original Article
A laboratory-based study examining the properties of silk fabric to evaluate its potential as a protective barrier for personal protective equipment and as a functional material for face coverings during the COVID-19 pandemicResearch Article Published on 2020-09-182022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] added Care clinical condition conditions conducted COVID-19 COVID-19 pandemic determine droplet droplets effective Effectiveness Efficacy equipment evaluate examined functional greater Health hydrophobic hydrophobicity Laboratory maintain many cases Mask Masks N95 respirator penetration Personal protective equipment PROTECT Protective repeated Respirator reuse surgical tested Transmission virus [DOI] 10.1371/journal.pone.0239531 PMC 바로가기 [Article Type] Research Article
Selected Lactobacillus strains isolated from sugary and milk kefir reduce Salmonella infection of epithelial cells in vitroarticle Published on 2016-09-302024-09-01 Journal: Benef Microbes [Category] 살모넬라증, [키워드] adhesion autoaggregation coaggregation hydrophobicity Invasion [Article Type] article
Genetic Variability and Phylogeny of Current Chinese Porcine Epidemic Diarrhea Virus Strains Based on Spike , ORF3 , and Membrane GenesResearch Article Published on 2014-01-222022-10-29 Journal: The Scientific World Journal [Category] Coronavirus, MERS, [키워드] amplified Analysis analyzed antigenicity changed Characteristics China Chinese conserved current death demonstrated different epidemic diarrhea Frame Gene Genes homology hydrophobicity Immunity isolate M gene membrane Mutation ORF ORF3 outbreak PEDV S gene sequence sequenced spike Spread strain subgroup suggested the disease the S protein the vaccine variant Variation virulence virulent virus widespread [DOI] 10.1155/2014/208439 PMC 바로가기 [Article Type] Research Article