Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-UpMedicine Published on 2021-12-242022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age-matched control analyzed anti-spike antibody anti-Spike IgG BNT162b2 boost Chronic hemodialysis close monitoring Cohort cohort analysis collected Control correlated COVID-19 COVID-19 infection dose ELISA exclusion Factor first dose fraction Hemodialysis hepatitis B higher risk IgA level IgG IgG level IgM immunosuppressive therapy lack longitudinal Lower maintenance mRNA BNT162b2 of BNT162b2 outcomes participant Patient patients performed persistence quantified receive Responder response resulting SARS-CoV-2 second dose sera Seroconversion seroconvert Seronegativity specific antibody vaccination Vaccine vaccine dose Vaccines while [DOI] 10.3389/fmed.2021.796676 PMC 바로가기 [Article Type] Medicine
Comparison of SARS-CoV-2-Specific Antibodies in Human Milk after mRNA-Based COVID-19 Vaccination and InfectionArticle Published on 2021-12-142022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] analyzed Antibody Response BNT162b2 BNT162b2 mRNA COVID-19 vaccine BNT162b2 vaccine both groups breastmilk COVID-19 detectable difference Human human milk IgA IgA level immunization (vaccination) immunoglobulin A Infant Infection lactating women longitudinal cohort study milk mother participant receive SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2-specific antibody secreted the antibody response the SARS-CoV-2 vaccination Vaccine Variability [DOI] 10.3390/vaccines9121475 PMC 바로가기 [Article Type] Article
Humoral protection to SARS-CoV2 declines faster in patients on TNF alpha blocking therapiesSARS-CoV2에 대한 체액 보호는 TNF 알파 차단 요법을 받는 환자에서 더 빨리 감소합니다Article Published on 2021-12-012022-09-11 Journal: RMD Open [Category] 변종, 진단, [키워드] Anti-spike anti-Spike IgG anti-TNF Antigen appearance Arthritis blockade booster booster vaccination booster vaccinations CD4+ T cell CD4+ T-cell chronic inflammatory disease chronic inflammatory diseases clinically Cohort controls COVID-19 Critical Decline declined Efficacy faster Frequency greater groups healthy controls healthy individual humoral immune response Humoral response humoral responses IgA level IgA levels IgG immune responses Inflammatory diseases lack mRNA vaccination Necrosis neutralization Neutralizing antibodies no differences pandemic Patient patients persistence receiving regimens response SARS-CoV2 second vaccination significantly T cell therapy TNF TNF alpha Treatment Tumor tumor necrosis tumor necrosis factor tumor necrosis factor inhibitors vaccination vaccine response vaccine responses variants while [DOI] 10.1136/rmdopen-2021-002008 PMC 바로가기 [Article Type] Article
Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain스페인 바르셀로나에있는 여름 학교에 다니는 어린이들로부터 타액에서 SARS-COV-2 로의 항체 전환율Research Article Published on 2021-11-232022-09-01 Journal: BMC Medicine [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] age anti-spike antibodies antibody Antibody conversion antibody profiling Antigen approach Asymptomatic Barcelona children collected contagious COVID-19 COVID-19 pandemic cross-reactive antibodies cumulative defined detect evaluated faster females FIVE Health Policies IgA IgA antibodies IgA antibody IgA level IgA levels IgG IgG level IgG levels IgM increase in individual infection rate initial isotype Luminex assay management MOST Non-invasive nucleocapsid Pandemics pediatric Population protective role public health recommendation reporting symptom required Result RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection School Schools significantly higher Spain supplementary material symptomatic individuals variants Viral viral epidemics Viral load Viral transmission [DOI] 10.1186/s12916-021-02184-1 PMC 바로가기 [Article Type] Research Article
Immunogenicity of BNT162b2 Vaccine in Patients with Inflammatory Bowel Disease on Infliximab Combination Therapy: A Multicenter Prospective StudyArticle Published on 2021-11-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age antibody azathioprine BNT162b2 clinical trial Combination combination therapy Concentration control group COVID-19 COVID-19 vaccination COVID-19 vaccine dose evaluate excluded group healthy IBD IgA IgA level IgA levels IgG immunogenicity Inflammatory bowel disease infliximab IQR median mRNA vaccine multicenter neutralizing antibody of BNT162b2 outcomes participant Participants Patient patients treated percentage positive Primary outcome Prospective Prospective Study PROTECT receiving recruited SARS-CoV-2 antibody SARS-CoV2 seroconverted Serologic response Sex significantly lower study group the study group the vaccine vaccination Vaccine [DOI] 10.3390/jcm10225362 PMC 바로가기 [Article Type] Article
COVID-19 mRNA Vaccination in Lactation: Assessment of Adverse Events and Vaccine Related Antibodies in Mother-Infant Dyads수유에서의 Covid-19 mRNA 백신 접종 : 마시어-영향 다이어드에서의 부작용 및 백신 관련 항체의 평가Immunology Published on 2021-11-032022-08-13 Journal: Frontiers in Immunology [Category] MERS, SARS, 임상, [키워드] addition Adverse adverse event age anti-RBD anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies antibodies antibody assessment automated Blood blood sample Blood samples BNT162b2 Breastfeeding Cohort collected COVID-19 COVID-19 mRNA Vaccination COVID-19 mRNA vaccine diagnosed with COVID-19 dose dyad ELISA first vaccination generate human milk IgA IgA level IgG antibodies IgG antibody IgM immune response immune responses immunoassay individual Infant Infants lactating lactation maternal plasma milk mother mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-based vaccine mRNA-based vaccines passive immunity PEGylated protein PEGylated proteins plasma prospective cohort Pylon 3D Questionnaires reported Result robust SARS-CoV-2 severe adverse event severe adverse events significant level significantly increased study period subset Symptom the vaccine transfer vaccination were assessed were measured [DOI] 10.3389/fimmu.2021.777103 PMC 바로가기 [Article Type] Immunology
Long-Term Persistence and Relevant Therapeutic Impact of High-Titer Viral-Neutralizing Antibody in a Convalescent COVID-19 Plasma Super-Donor: A Case Report회복기 COVID-19 혈장 슈퍼 기증자에서 고역가 바이러스 중화 항체의 장기 지속성 및 관련 치료 영향: 사례 보고서Case Reports Published on 2021-08-232022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] Administered anti-S antibody Biosafety Level 3 Case report clinical setting convalescent correlated correlation COVID-19 criteria Donor enrolled expected FIVE Follow-up Hyperimmune plasma IgA IgA level IgA levels IgG and IgM Impact independent Microneutralization test National National Cancer Institute Neutralizing activity Neutralizing antibodies Neutralizing titer Patient patient with COVID-19 plasma RBD/ACE2-binding inhibition test report Rome SARS-CoV-2 SARS-CoV-2 patient serum severe COVID-19 symptoms steadily decreased the patient transfusion unit were measured [DOI] 10.3389/fimmu.2021.690322 PMC 바로가기 [Article Type] Case Reports
Codominant IgG and IgA expression with minimal vaccine mRNA in milk of BNT162b2 vaccineesArticle Published on 2021-08-192022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] adverse effect Antenatal BNT162b2 vaccine Breastfeeding COVID-19 COVID-19 vaccination disease dose Efficacy Evidence expression had no human milk IgA IgA level IgG IgG antibody IgG titer Infant Influenza initial lactating mother mRNA mRNA vaccination of BNT162b2 Outcomes research produced profile Protective antibody protective immunity recommendation reported SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody secreted significant increase subsequent Support the vaccine transfer vaccination Vaccine vaccinee viral infection women [DOI] 10.1038/s41541-021-00370-z PMC 바로가기 [Article Type] Article
COVID‑19 vaccination and IgG and IgA antibody dynamics in healthcare workers의료 종사자의 COVID-19 예방 접종 및 IgG 및 IgA 항체 역학Article Published on 2021-08-012022-09-12 Journal: Molecular medicine reports [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome all subject antibodies antibody association both groups coronavirus disease COVID‐19 demonstrated first dose healthcare worker IgA IgA level IgG Immunoglobulin implementation outbreak Patient second dose Seroconversion severe acute respiratory syndrome coronavirus‑2 statistically subject vaccination Vaccine [DOI] 10.3892/mmr.2021.12217 PMC 바로가기 [Article Type] Article
One Year after Mild COVID-19: The Majority of Patients Maintain Specific Immunity, But One in Four Still Suffer from Long-Term SymptomsArticle Published on 2021-07-272022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute phase analyses antibody cellular immunity central memory complications Concentration correlation COVID-19 detectable develop Follow-up headache humoral Humoral immunity IgA IgA level IgG antibody immune immune responses Immunity Immunological memory investigated long-lasting loss of smell/taste marker Mild Older age participant Participants Patient persistent persistent symptoms persists remained reported SARS-CoV-2 Specific Still Symptom Symptoms T-cell T-cell responses T-helper cell Year [DOI] 10.3390/jcm10153305 PMC 바로가기 [Article Type] Article