Prolonged COVID-19 in an Immunocompromised Patient Treated with Obinutuzumab and Bendamustine for Follicular LymphomaArticle Published on 2022-08-152022-11-15 Journal: Internal medicine (Tokyo, Japan) [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] anti-spike protein IgG Bendamustine coronavirus COVID-19 COVID-19 symptom COVID-19 symptoms detect Dexamethasone discharged exacerbated follicular Follicular lymphoma Immunocompromised Immunocompromised patient Immunocompromised patients lymphoma obinutuzumab obinutuzumab and bendamustine observation Patient Prolonged Prolonged COVID-19 Remdesivir SARS-CoV-2 vaccination subsequent Symptom the disease the patient treated [DOI] 10.2169/internalmedicine.9136-21 PMC 바로가기
Seroconversion following the first, second, and third dose of SARS-CoV-2 vaccines in immunocompromised population: a systematic review and meta-analysis면역저하 집단에서 SARS-CoV-2 백신의 1차, 2차, 3차 접종 후 혈청전환: 체계적인 검토 및 메타분석Review Published on 2022-08-082022-09-12 Journal: Virology Journal [Category] SARS, 진단, [키워드] 95% CI administration Analysis article Autoimmune Autoimmune disease booster dose conditions conducted COVID-19 COVID-19 vaccine database develop dose dose administration Efficacy etiology evaluate first dose General population heterogeneity high-risk population higher risk Immunity Immunocompromised Immunocompromised patient investigated item less lowest malignancy material Meta-analysis mRNA mRNA vaccine observational study Patient patients Prevalence R software Reporting review rising SARS-CoV-2 SARS-CoV-2 vaccine searched second dose sensitivity analysis Seroconversion Severe COVID-19 Infection subgroup analysis systematic review the vaccine transplantation vaccination Vaccine was performed Web of Science [DOI] 10.1186/s12985-022-01858-3 PMC 바로가기 [Article Type] Review
Patients with CLL have a lower risk of death from COVID-19 in the Omicron eraCLL 환자는 오미크론 시대에 COVID-19로 인한 사망 위험이 더 낮습니다Article Published on 2022-08-042022-09-11 Journal: Blood [Category] SARS, 변종, [키워드] 30-Day mortality acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age antiviral therapy chronic lymphocytic leukemia CLL Cohort cohort of patient Comorbidity Contact coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death declined described disease course dominance General population high mortality hospital Hospitalization hospitalizations Immunocompromised Immunocompromised patient Immunocompromised patients intensive care leukemia lower risk Lymphocytic leukemia omicron Omicron variant outcome Patient population-based cohort positive Previous studies previous study remained reported SARS-CoV-2 SARS-CoV-2 test severe acute respiratory syndrome Coronavirus shown significantly tested variant [DOI] 10.1182/blood.2022016147 PMC 바로가기 [Article Type] Article
Homotypic and heterotypic immune responses to Omicron variant in immunocompromised patients in diverse clinical settings다양한 임상 환경에서 면역 저하 환자의 오미크론 변이체에 대한 동형 및 이형 면역 반응Article Published on 2022-08-042022-09-11 Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료법, [키워드] CD4 CD8 Cellular immune response clinical setting comparable controls cross-neutralization D614G Delta Delta variants disease severity dose Host humoral identify immune immune response immune responses Immunocompromised Immunocompromised patient Immunocompromised patients implication Infection magnitude neutralization neutralizing antibody omicron Organ transplant Patient patients peptide peptide pools Pseudovirus neutralization assay Re-infection recipient response responses risk of infection SARS-CoV-2 severe COVID-19 subset T-cell Response T-cell responses uninfected Vaccine variant variants [DOI] 10.1038/s41467-022-32235-x PMC 바로가기 [Article Type] Article
Factors that predict severity of infection and seroconversion in immunocompromised children and adolescents with COVID-19 infectionCOVID-19 감염으로 면역저하된 소아 및 청소년에서 감염 및 혈청전환의 중증도를 예측하는 요인Observational Study Published on 2022-08-032022-09-12 Journal: Frontiers in Immunology [Category] SARS, 임상, 진단, [키워드] Absolute lymphocyte count absolute neutrophil count Analysis ANC anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Antibody Response blood sample body mass index Cancer Cell Chemotherapy children Clinical severity comorbid condition COVID COVID 19 COVID-19 infection Critical Cutoff defined determine died Factor FIVE Hematologic malignancy Hematological malignancy high-risk population Hospitalized ICU Immunocompromised Immunocompromised patient immunosuppressive Infection Laboratory less Level lowest median moderate multivariable model observation outcome outcomes Patient patients PCR Pediatric patient predict Predictive receiving required Respiratory Support SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection Seroconversion seroconversion rate severity Severity of infection stem cell transplant steroid the patient therapy treated univariable vaccination variable was used with COVID-19 [DOI] 10.3389/fimmu.2022.919762 PMC 바로가기 [Article Type] Observational Study
Sotrovimab drives SARS-CoV-2 omicron variant evolution in immunocompromised patientsSotrovimab, 면역 저하 환자에서 SARS-CoV-2 오미크론 변이 진화 촉진Article Published on 2022-08-012022-09-11 Journal: The Lancet. Microbe [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Evolution Immunocompromised patient Omicron variant SARS-CoV-2 Sotrovimab [DOI] 10.1016/S2666-5247(22)00120-3 PMC 바로가기 [Article Type] Article
Prolonged shedding of infectious viruses with haplotype switches of SARS-CoV-2 in an immunocompromised patient면역 저하 환자에서 SARS-CoV-2의 일배체형 스위치로 감염성 바이러스의 장기간 배출Case Reports Published on 2022-07-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] accumulated acquired immunity Bendamustine Clinical course Complete Complete Remission convalescent stage COVID-19 COVID-19 case COVID-19 infection COVID-19 pneumonia detectable eight episode episode of follicular Follicular lymphoma Haplotype Host immune Immunity Immunocompromised Immunocompromised host Immunocompromised patient Infectious virus infectiousness Infectivity initial kinetic long-lasting lymphoma management mechanical ventilation Non-synonymous mutation Patient Pneumonia Prolonged raised required Respiratory failure rituximab SARS-CoV-2 SARS-CoV-2 variants spike gene suppressed tested the SARS-CoV-2 variants Viral Viral kinetic. Viral RNA [DOI] 10.1016/j.jiac.2022.04.004 PMC 바로가기 [Article Type] Case Reports
Viral culture and immunofluorescence for the detection of SARS-CoV-2 infectivity in RT-PCR positive respiratory samplesRT-PCR 양성 호흡기 샘플에서 SARS-CoV-2 감염성 검출을 위한 바이러스 배양 및 면역형광Article Published on 2022-07-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] cells correlation COVID-19 Ct value Culture gold gold standard Immunocompromised Immunocompromised patient Immunocompromised patients immunofluorescence indicate individuals Infection prevention infective Infectivity inoculated Isolation median Other respiratory viruses Patient positive positive correlation positive individuals Prevention and control Probability protocol reference method respiratory sample respiratory viruses RT-PCR RT-PCR Ct SARS-CoV-2 SARS-CoV-2-positive individual severe COVID-19 subject Symptom symptom onset Vero E6 VERO E6 cells viral culture Viral isolation virus [DOI] 10.1016/j.jcv.2022.105167 PMC 바로가기 [Article Type] Article
Paxlovid (Nirmatelvir/Ritonavir) and Tacrolimus Drug-Drug Interaction in a Kidney Transplant Patient with SARS-2-CoV infection: A Case ReportArticle Published on 2022-07-012022-11-15 Journal: Transplantation proceedings [Category] COVID19(2023년), SARS, 치료제, [키워드] Acute kidney injury acute respiratory syndrome addition adverse effects Affect antiviral medication approved Awareness Case report Combination Community Consulting coronavirus disease dose drug-drug interaction Efficiency Emergency use enzyme health systems Immunocompromised patient Immunosuppressive medication increase induce inhibit inhibitor interactions kidney transplant medication metabolites New P450 pandemic Patient Paxlovid physician Prevent receive receiving recipient reduction rejection report risk Ritonavir robust SARS-CoV-2 serum creatinine Side effects Symptoms tacrolimus tested Transplant treat treated Treatment [DOI] 10.1016/j.transproceed.2022.04.015 PMC 바로가기
Reduced neutralizing antibody potency of COVID-19 convalescent vaccinated plasma against SARS-CoV-2 Omicron variantSARS-CoV-2 오미크론 변이체에 대한 COVID-19 회복기 백신 접종 혈장의 중화 항체 효능 감소Article Published on 2022-07-012022-09-11 Journal: Vox Sanguinis [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] anti-IgG Anti-S1 antibody assays B.1 best binding coefficient collected convalescent convalescent plasma correlated correlation coefficient COVID-19 D614G Donor fraction highest IgG IgG level Immunocompromised patient Immunocompromised patients Infection median Mutation NAb Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Omicron variant plasma Quantitative reduced relationship resulting SARS-CoV-2 selected significantly lower Spearman Strains threshold titre titres vaccination variant [DOI] 10.1111/vox.13279 PMC 바로가기 [Article Type] Article