Efficacy of antibody response following the vaccination of SARS-CoV-2 infected and noninfected healthcare workers by two-dose inactive vaccine against COVID-19COVID-19에 대한 2회 접종 불활성 백신에 의한 SARS-CoV-2 감염 및 비감염 의료 종사자의 백신 접종 후 항체 반응의 효능Article Published on 2022-06-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody antibody Antibody Response Antibody responses appearance classical Comorbidities concerning coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Day demographics detect Efficacy first dose healthcare worker IgG antibodies IgG level IgG levels immunogenicity Immunosuppression inactive individuals infected with SARS-CoV-2 Infection information investigated majority Neutralizing activity positive postvaccination produced rapid increase SARS-CoV-2 screened second dose second vaccination seropositive seropositive individual seropositive individuals Seropositivity significantly higher Sinovac subject subjects Support Symptoms titers vaccination Vaccine virus [DOI] 10.1002/jmv.27649 PMC 바로가기 [Article Type] Article
Immune response of booster doses of BBIBP-CORV vaccines against the variants of concern of SARS-CoV-2SARS-CoV-2의 우려 변종에 대한 BBIBP-CORV 백신의 추가 용량의 면역 반응Observational Study Published on 2022-06-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] (alpha Alpha Antibody titer Antibody titers approved BBIBP-CorV Beta booster booster dose booster doses Cohort COVID-19 COVID-19 vaccination COVID-19 vaccinations dose doses Evidence fold immune response inactivated Inactivated vaccine Inactivated Vaccines inactive individual Lineage lineages neutralization test Neutralizing antibodies Neutralizing antibody titer neutralizing antibody titers neutralizing effect observational study offered plaque pooled serum primary dose primary doses PRNT recipient recipients reduction reduction in sample pool SARS-CoV-2 SARS-CoV-2 variants serum serum sample serum samples statistically significant Test the SARS-CoV-2 Vaccinations Vaccine vaccine cohort variant variants variants of concern was done Wuhan [DOI] 10.1016/j.jcv.2022.105161 PMC 바로가기 [Article Type] Observational Study
Randomised controlled trial of a behaviour change physiotherapy intervention to increase physical activity following hip and knee replacement: the PEP-TALK trialRandomized Controlled Trial Published on 2022-05-312022-10-05 Journal: BMJ Open [Category] 임상, [키워드] 1:1 95% CI activity adult orthopaedics adverse event age allocation Blinding Care cognitive Comorbidities Compliance contributed Controlled trial COVID-19 pandemic Effectiveness eligibility English Evidence hip hospital hospitals inactive individual Intervention knee Los Angele National Health Service nine no difference outcome Pain participant physical activity Physical inactivity Pragmatic proportion Psychological distress Quality of life randomised randomised controlled receive reduced rehabilitation rheumatology Sample size score secondary outcome Self-efficacy Trial Two-arm University of California usual care women [DOI] 10.1136/bmjopen-2022-061373 PMC 바로가기 [Article Type] Randomized Controlled Trial
Newly Emerged Antiviral Strategies for SARS-CoV-2: From Deciphering Viral Protein Structural Function to the Development of Vaccines, Antibodies, and Small MoleculesSARS-CoV-2에 대한 새로 등장한 항바이러스 전략: 바이러스 단백질 구조 기능 해독에서 백신, 항체 및 소분자 개발까지Review Published on 2022-05-292022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis antibody antibody cocktail antibody treatment Antiviral caused chemical compounds clustered regularly interspaced short palindromic repeats compounds contribute coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 infection CRISPR development disease pathogenesis DNA dual exploration focus function functional Health Health crisis host cells inactive Infection inhibitors life cycle molecule monoclonal antibodies monoclonal antibody mRNA nonstructural proteins palindromic repeat Particles peptide-based Protein protein-based vaccine Protein-based vaccines Proteins provide research findings respiratory RNA vaccines SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 genome severe acute respiratory syndrome Coronavirus single-stranded Strategy structural proteins structure-function systematic review target targeted therapy targets the SARS-CoV-2 genome therapeutic option Therapeutic strategies therapy Treatment Vaccine Vaccine development Vaccines Viral viral life cycle Viral protein Viral proteins viral replication virus [DOI] 10.3390/ijms23116083 PMC 바로가기 [Article Type] Review
D3AI-CoV: a deep learning platform for predicting drug targets and for virtual screening against COVID-19D3AI-CoV: 약물 표적 예측 및 COVID-19에 대한 가상 스크리닝을 위한 딥 러닝 플랫폼Article Published on 2022-05-132022-09-11 Journal: Briefings in Bioinformatics [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] approach AUC characteristic composed Compound computer-aided drug design COVID-19 COVID-19 treatment cycle D3AI-CoV deep learning Drug discovery Drug repurposing Drug screening drug target DrugBank drugs effective drug IMPROVE inactive independent mechanism online tool platform powerful tool Predictive receiver receiver operating characteristic reported target target prediction target protein Treatment Virtual screening web application [DOI] 10.1093/bib/bbac147 PMC 바로가기 [Article Type] Article
Vaccine Side Effects Following COVID-19 Vaccination Among the Residents of the UAE-An Observational StudyObservational Study Published on 2022-05-062022-10-04 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI adverse (side) effects. adverse effect adverse event age analyzed average clinical trials comorbid conditions Comorbidities conducted COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine difference Effect Effects Evidence Factor fatigue female gender Gender headache higher odd inactivated inactive individual injection less Mild mRNA mRNA vaccine Odds ratio Pain Pfizer Pfizer-BioNTech Pfizer-BioNTech vaccine recipient recipients reported resident Safe SARS-CoV-2 severity side Side effect Sinopharm Sinopharm vaccine statistically significant survey platform Treatment Vaccine [DOI] 10.3389/fpubh.2022.876336 PMC 바로가기 [Article Type] Observational Study
Aquaporin-4 protein antibody-associated optic neuritis related to neuroendocrine tumor after receiving an inactive COVID-19 vaccine코로나19 비활성화 백신 접종 후 신경내분비종양과 관련된 아쿠아포린-4 단백질 항체 관련 시신경염Case Reports Published on 2022-05-012022-09-12 Journal: Indian journal of ophthalmology [Category] MERS, 진단, [키워드] Affect Aquaporin-4 protein antibody Autoimmune caused COVID-19 COVID-19 vaccine demyelinating disorder disease disorder gastric neuroendocrine tumor inactive inactive COVID-19 vaccine neuroendocrine Neuromyelitis Optic neuritis Protein receiving [DOI] 10.4103/ijo.IJO_2494_21 PMC 바로가기 [Article Type] Case Reports
Balance performance analysis after the COVID-19 quarantine in children aged between 8 and 12 years old: Longitudinal studyObservational Study Published on 2022-05-012022-10-05 Journal: Gait & posture [Category] 임상, [키워드] activities addition age analysed Analysis balance benefit carried caused changes in children condition Control Control postural Corona COVID-19 demonstrated drastic reduction evaluated healthy children home quarantine impairment inactive infections lockdown longitudinal study Loss moderate not differ pandemic performed physical activity Physical inactivity physically quarantine reduction in Sample size Spain stability statistically significant statistically significant difference was performed [DOI] 10.1016/j.gaitpost.2022.03.019 PMC 바로가기 [Article Type] Observational Study
Development of a colorimetric assay for the detection of SARS-CoV-2 3CLpro activitySARS-CoV-2 3CLpro 활성 검출을 위한 비색 분석법 개발Article Published on 2022-04-292022-09-11 Journal: Biochemical Journal [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] 3CLpro acute respiratory syndrome coronavirus assay development. AuNP causative agent cellular conditions coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coronavirus replication COVID COVID 19 COVID-19 detect development diagnostic diagnostic test diagnostic testing disease ENCODE exogenously expressed global pandemic gold Gold nanoparticle HEK293T highlight human cells in vitro inactive mutant peptide point-of-care protease Protease activity Protein purified respiratory SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection sensitivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 virus [DOI] 10.1042/BCJ20220105 PMC 바로가기 [Article Type] Article
Assessing humoral immune response after two doses of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthcare workers의료 종사자의 비활성화된 SARS-CoV-2 백신(CoronaVac) 2회 접종 후 체액성 면역 반응 평가Observational Study Published on 2022-04-012022-09-11 Journal: Public health [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, [키워드] Abbott absence age anti-Spike IgG antibody Assessing blood sample Blood samples CoronaVac COVID-19 pandemic cutoff value declined detection dose female first dose greater HCW HCWs healthcare worker Healthcare workers highest humoral immune response Humoral immunity Immunity immunoassay immunogenic immunogenicity Immunoglobulin Immunoglobulin G inactivated inactive Infection investigated Ireland male men Microparticle observational study performed positive prospective observational study receptor Receptor-binding domain reported risk S1 subunit SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 vaccine second dose second dose of vaccine Seropositivity significantly Spike protein susceptible the receptor-binding domain the S1 subunit the spike protein vaccination Vaccine virus was performed women [DOI] 10.1016/j.puhe.2022.01.011 PMC 바로가기 [Article Type] Observational Study