Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes
Article
[키워드] abundance
acute phase
acute respiratory syndrome
Alter
Analysis
approach
assays
body mass index
C-reactive protein
circulating
clinical decision
Compromised
coronavirus
COVID-19
COVID-19 pathogenesis
COVID-19 patient
creatinine
criterion
Critical
Critically ill
cut-off value
determine
disease
disrupt
driven by
dysregulation
energy-related metabolites
evaluated
Extracellular
fluorometric quantification
Glucose
Health
Host
Host immune response
immune response
implicated
IMPROVE
Increased
independent predictor
Infection
Lactate
mechanisms
metabolism
metabolite
metabolomics
mitochondrial
outcome
outcomes
Patient
Potential biomarker
Prognosis
Prognostic marker
provided
pyruvate
quantification
Quantitative
recruited
risk
SARS-CoV-2
SARS-COV-2 infection
semi-targeted metebolomics.
serum
severe COVID-19 illness
severity
Signaling
Stratification
Support
validation cohort
virus
[DOI] 10.3389/fimmu.2022.912579 PMC 바로가기
[DOI] 10.3389/fimmu.2022.912579 PMC 바로가기