Epitope-Evaluator: An interactive web application to study predicted T-cell epitopesArticle Published on 2022-08-262022-11-16 Journal: PLoS ONE [Category] SARS, 변종, [키워드] alleles amino acid sequence antigens candidate class Cutoff Delta distribution downloaded epitope Epitopes facilitate histocompatibility complex Interpretation MHC MHC alleles Multiple omicron parameters peptide predict predicted programming Protein protein sequence proteome provide selected spike T-cell epitope T-cell epitopes the SARS-CoV-2 variant Wuhan [DOI] 10.1371/journal.pone.0273577 PMC 바로가기
Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection니코틴은 SARS-CoV-2 감염에 대한 유의한 세포 보호 활성이 없습니다Article Published on 2022-08-182022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] carried Clinical data coronavirus disease COVID-19 cytotoxicity demonstrated had no Hypothesis Infection Interpretation Nicotine pandemic Prevent question reported risk of COVID-19 SARS-COV-2 infection These cells Vero E6 cell [DOI] 10.1371/journal.pone.0272941 PMC 바로가기 [Article Type] Article
Metacells untangle large and complex single-cell transcriptome networksMetacells는 크고 복잡한 단일 세포 전사체 네트워크를 풉니다.Article Published on 2022-08-132022-09-11 Journal: BMC Bioinformatics [Category] 유전자 메커니즘, [키워드] accelerate analysis build Cell cell type cell type annotation cells Clustering Coarse-graining complex Computational biology construction correlation COVID-19 patient COVID-19 patients demonstrated develop differential expression downstream analyses downstream analysis facilitate framework heterogeneous IMPROVE imputation inherent integration Interpretation less Metacells offer populations redundancy RNA RNA sequencing scRNA-seq scRNA-seq data significantly single-cell Single-cell RNA sequencing Single-cell transcriptomics Single-cell transcriptomics. SuperCell tissue Transcriptome transcriptomic unique Visualization [DOI] 10.1186/s12859-022-04861-1 PMC 바로가기 [Article Type] Article
Modeling Global COVID-19 Dissemination Data After the Emergence of Omicron Variant Using Multipronged Approaches다각적 접근 방식을 사용하여 오미크론 변이체 출현 후 글로벌 COVID-19 보급 데이터 모델링Article Published on 2022-08-102022-09-11 Journal: Current microbiology [Category] SARS, 변종, [키워드] among others approach basic Behavior collected compartmental model country COVID-19 COVID-19 dissemination COVID-19 pandemic data set data sets determine develop disease spread distribution drop emergence Factor fitting followed by Formula human behavior incidence increase in Infection infection rate infection rates information Interpretation management measure modeling number omicron pandemic reproduction Research Sery Spread statistical text the disease time Transmission vaccination vaccination efficacy variants of SARS-CoV-2 vulnerable population yielding [DOI] 10.1007/s00284-022-02985-4 PMC 바로가기 [Article Type] Article
Indicators of recent COVID-19 infection status: findings from a large occupational cohort of staff and postgraduate research students from a UK university최근 COVID-19 감염 상태의 지표: 영국 대학의 직원 및 대학원 연구원으로 구성된 대규모 직업 집단의 결과Article Published on 2022-08-092022-09-11 Journal: BMC Public Health [Category] SARS, 치료기술, [키워드] Algorithm antibodies antibody Antibody detection Antibody test antibody test result Antibody testing antibody tests assist classification Cohort Cohort studies cohort study Concordance contribute core COVID-19 COVID-19 case COVID-19 cases COVID-19 illness COVID-19 infection COVID-19 serological testing criteria definitive diagnosis described Descriptive statistics difference evaluate Evidence FIVE followed by Health Indicator Interpretation lateral flow likelihood London meeting overlap participant Participants positive positive result positive symptom predicted Prevalence proportion Public public health public health. report reported Research serological Serological testing significantly Support suspicion Symptom Symptoms test cassette test result to define vaccination [DOI] 10.1186/s12889-022-13889-0 PMC 바로가기 [Article Type] Article
Statistical framework to support the epidemiological interpretation of SARS-CoV-2 concentration in municipal wastewater도시 폐수 내 SARS-CoV-2 농도의 역학 해석을 지원하는 통계적 프레임워크Article Published on 2022-08-052022-09-11 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Bayesian Canada Concentration coronavirus COVID-19 pandemic Data analysis data set detect detectable epidemiological functional infected individual infected individuals Interpretation observation observations Previous studies Ribonucleic acid RNA SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity statistical statistical framework Support Surveillance surveillance data trajectory Viral concentration viral concentrations virus wastewater [DOI] 10.1038/s41598-022-17543-y PMC 바로가기 [Article Type] Article
New Phylogenetic Models Incorporating Interval-Specific Dispersal Dynamics Improve Inference of Disease Spread간격별 분산 역학을 통합한 새로운 계통 발생 모델은 질병 확산의 추론을 향상시킵니다.Article Published on 2022-08-032022-09-11 Journal: Molecular Biology and Evolution [Category] SARS, 유전자 메커니즘, [키워드] Alter average biogeographic history contrary COVID-19 COVID-19 pandemic dataset datasets develop dispersal Dynamics early phase Efficacy Epidemiology event Evidence failure IMPROVE Inference Interpretation Intervention measure mitigate Model New pandemic parameter phylodynamic phylodynamic models phylogeography phylogeography. provide SARS-CoV-2 significantly Simulation Spread Statistics temporal dynamics Variation [DOI] 10.1093/molbev/msac159 PMC 바로가기 [Article Type] Article
Assessing and improving the validity of COVID-19 autopsy studies – A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analysesResearch article Published on 2022-08-022022-10-05 Journal: EBioMedicine [Category] Coronavirus, SARS, 치료기술, [키워드] Alliance Analysis analysis antibody approach Assessing Autopsy autopsy study available data Berlin cell line cellular structure center correlated COVID-19 criteria education Effect Effects electron microscopy evaluated finding foundation funding Guidance help high variability highest IHC immune response immunohistochemistry Interpretation Microscopy Ministry of Health multicentre organ organ damage pathology pathophysiology positive correlation Protein provided Quantitative recommendation reproducibility RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleocapsid SARS-CoV-2 viral RNA Sensitivity and specificity specificity the SARS-CoV-2 tissue tissues university Validity Variability Viral protein virus [DOI] 10.1016/j.ebiom.2022.104193 [Article Type] Research article
Temporal lineage replacements and dominance of imported variants of concern during the COVID-19 pandemic in Kenya Research Published on 2022-08-012022-10-05 Journal: Communications Medicine [Category] 진단, 치료기술, [키워드] Analysis B.1 B.1 lineage B.1.1 Beta circulating variant COVID-19 epidemic COVID-19 pandemic Delta disease severity dominant European expand FIVE Genome genomes highlight Interpretation Kenya Lineage omicron phenotype remained Result SARS-CoV-2 lineage subsequent Surveillance Temporal Transmissibility Vaccine variant variants of concern virulence VoC Wave [DOI] 10.1038/s43856-022-00167-8 [Article Type] Research
Evaluation of a potential prognostic parameter for the inflammatory status in COVID-19 patients: The inflammatory protein ratioCOVID-19 환자의 염증 상태에 대한 잠재적인 예후 매개변수 평가: 염증 단백질 비율Article Published on 2022-08-012022-09-11 Journal: Electrophoresis [Category] COVID19(2023년), SARS, 치료기술, [키워드] albumin all the patients ANOVA C-reactive protein calculated Chain Reaction controls coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient CRP D-dimer dimer fibrinogen Globulin hospitalized patient Human plasma immuno-turbidimetric assay immunoassay Inflammatory inflammatory protein inflammatory state inflammatory status Interpretation involved Kruskal-Wallis mathematical Nasopharyngeal swab nasopharyngeal swabs parameter parameters Pearson performed polymerase chain polymerase chain reaction prognostic proportionality Protein qualitative test quantified real time real time Polymerase Chain Reaction RNA RT-PCR SARS-CoV-2 SARS-CoV-2 positivity separated Serum protein serum protein electrophoresis. serum proteins Significant significantly Spearman the patient unique variance [DOI] 10.1002/elps.202100396 PMC 바로가기 [Article Type] Article