New-onset refractory status epilepticus as an early manifestation of multisystem inflammatory syndrome in adults after COVID-19Case Reports Published on 2022-05-012023-07-08 Journal: Epilepsia [Category] COVID19(2023년), [키워드] COVID-19 IVIG Multisystem inflammatory syndrome NORSE SARS-CoV-2 status epilepticus [DOI] 10.1111/epi.17231 PMC 바로가기 [Article Type] Case Reports
Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-CCOVID-19가 있는 성인 및 소아 환자와 MIS-C를 가진 어린이에서 이전에 자가면역과 연관되었던 단백질에 대한 자가항체Article Published on 2022-03-112022-09-11 Journal: Frontiers in Immunology [Category] MERS, 진단, 치료제, [키워드] administration Against Analysis antibody Antigen antigens ATPase autoantibodies autoantibody autoantigen Autoantigens Autoimmune Autoimmune disease Autoimmune diseases Autoimmunity both groups children COVID-19 declined defined detect diabetes gastritis human protein human proteins IgA antibodies IgA antibody IgG Immunoglobulin in both group in vivo Inflammatory insulin-dependent diabetes Intravenous immunoglobulin IVIG Kawasaki disease KCNRG KLHL12 lung MIS-C MIS-C multisystem inflammatory syndrome in children monitoring Patient patients patients with COVID-19 Protein responsible Ro60 subset syndrome target therapy troponin undetectable while with COVID-19 [DOI] 10.3389/fimmu.2022.841126 PMC 바로가기 [Article Type] Article
The outcome of using intravenous immunoglobulin (IVIG) in critically ill COVID-19 patients’: a retrospective, multi-centric cohort study중환자 COVID-19 환자에서 IVIG(정맥 면역글로불린) 사용 결과: 후향적, 다중심 코호트 연구Multicenter Study Published on 2022-02-032022-09-12 Journal: European Journal of Medical Research [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Analysis analysis of variance ANOVA cohort study coronavirus COVID-19 COVID-19 admission COVID-19 pandemic COVID-19 patient COVID-19 patients Critically ill critically ill patients dosage dose duration of hospitalization effective Efficacy evaluated ICU independent indicated initial intensive care Intravenous immunoglobulin intubated patients IVIG mechanical ventilation medium medium dose mortality rate no significant difference outcome pandemic Patient patients Pneumonia Result retrospective significantly standard treatment subgroup suggested three group Treatment two group two groups was performed [DOI] 10.1186/s40001-022-00637-8 PMC 바로가기 [Article Type] Multicenter Study
Management skin manifestation of multisystem inflammatory syndrome associated with SARS-CoV-2SARS-COV-2와 관련된 다중 시스템 염증 증후군의 관리 피부 증상Case Reports Published on 2022-01-062022-09-01 Journal: Virology Journal [Category] 진단, [키워드] A multisystem inflammatory syndrome Affect Antibiotics Brain children clinical conditions Contact COVID-19 COVID-19 infection Dermatology described develop Diagnosis discharged disease effective emergency department Europe eyes Fever headache high fever Hospitalization Immunoglobulin indicated infected with SARS-CoV-2 Infection Inflammatory Initially intravenous Intravenous immunoglobulin IVIG joint joint pain kidney Laboratory laboratory findings lung male Methylprednisolone MIS MIS-C morbidity and mortality nausea organ Pain Paracetamol Patient pulse radiological reducing SARS-CoV-2 skin skin lesion skin lesions syndrome tissue inflammation Treatment USA weakness with COVID-19 [DOI] 10.1186/s12985-021-01736-4 PMC 바로가기 [Article Type] Case Reports
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent DonorsMedical Technology Published on 2022-01-052022-11-01 Journal: Frontiers in Medical Technology [Category] COVID-19, [키워드] ACE2-RBD anti-RBD anti-SARS-CoV-2 biochemical BNT162b2 BNT162b2 vaccine caprylic acid Characteristics characterization Concentration Concordance convalescent plasma COVID-19 COVID-19 convalescent donor COVID-19 pandemic Donor Effectiveness Efficacy and safety feasible Formulation Hyperimmune plasma hyperimmune polyclonal antibodies immunization immunized Immunoglobulin immunological Immunosuppression in vitro individual inhibitory concentration Intravenous immunoglobulin IVIG neutralizing antibody Passive immunotherapy Patient Pfizer-BioNTech physicochemical plaque reduction neutralization plasma Precipitation produced profile prophylactically SARS-CoV-2 therapeutic Vaccine [DOI] 10.3389/fmedt.2021.772275 PMC 바로가기 [Article Type] Medical Technology
Patient and Clinical Factors at Admission Affect the Levels of Neutralizing Antibodies Six Months after Recovering from COVID-19입원시 환자 및 임상 적 요인은 COVID-19에서 회복 한 6 개월 후 중화 항체 수준에 영향을 미칩니다.Article Published on 2022-01-022022-09-01 Journal: Viruses [Category] 진단, 치료기술, [키워드] Accuracy Admission AUC value average blood urea clinical Clinical treatment Comorbidity Concentration contribute convalescent coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) Corticosteroid Corticosteroids COVID-19 CRP diabete diabetes discharge Factor fibrinogen Guidance individual IVIG Level majority median mixture models Month NAb NAbs Neutralizing antibodies neutralizing antibody neutralizing antibody (NAb) Patient PCT Predictive proportion ROC analysis sensitivity severe acute respiratory syndrome coronavirus (SARS-CoV-2) specificity the median therapy Tongji Hospital two group two groups urea Wuhan Wuhan, China [DOI] 10.3390/v14010080 PMC 바로가기 [Article Type] Article
Summary report of seven cases of COVID-19 infection in renal transplant recipients신장이식 수혜자 코로나19 감염 7건 요약 보고Article Published on 2021-12-012022-09-11 Journal: Transplant immunology [Category] MERS, SARS, 진단, 치료제, [키워드] Acute kidney injury adjusted adopted Allograft Antibiotics antiviral drugs Asymptomatic Asymptomatic carrier Asymptomatic carriers clinical manifestations coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Critical critical patients died different clinical manifestations discharged ENhance FIVE Health High-dose Immunity Immunoglobulin Immunosuppressant immunosuppressants immunosuppressive agent Immunosuppressive agents infected with COVID-19 Infection Inflammation inhibit Intravenous immunoglobulin Isolation IVIG low-dose management Methylprednisolone Mild mild patients moderate moderate or severe patients one patient outcome Patient patients with COVID-19 Prognosis recipient reduced rejection renal Renal transplant reported reversal SARS-CoV-2 SARS-CoV2 Seven severe patients therapy treated Treatment was used were used [DOI] 10.1016/j.trim.2021.101445 PMC 바로가기 [Article Type] Article
Modelling the concentration of anti-SARS-CoV-2 immunoglobulin G in intravenous immunoglobulin product batches정맥주사용 면역글로불린 제품 배치에서 항-SARS-CoV-2 면역글로불린 G의 농도 모델링Research Article Published on 2021-11-292022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus anti-SARS-CoV-2 anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibody antibody half-life antibody levels Antibody titre anticipated binding Concentration convalescent convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 Diseases Donor early phase elevated expected group half-life IgG Immunoglobulin implication incidence indicated Intravenous immunoglobulin IVIG mathematical mathematical model measurement parameter Patient Phadia physician plasma plasma concentration predict produced reactivity Result retained SARS-CoV-2 SARS-CoV-2 vaccination status Study design the mean Vaccination Status were used [DOI] 10.1371/journal.pone.0259731 PMC 바로가기 [Article Type] Research Article
Pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 symptoms in IranCase Series Published on 2021-11-262022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] antivirals Combination complications COVID-19 diagnosed discharged Fever healthy hospital Hospitalization immune Inflammatory intravenous Iran irritability IVIG Laboratory tests material pediatric Pediatric patient physician PIMS-TS raised refusal SARS-CoV-2 screened Symptom syndrome the patient treated Treatment [DOI] 10.2217/fvl-2021-0156 PMC 바로가기 [Article Type] Case Series
Update on Intravenous Immunoglobulin in Neurology: Modulating Neuro-autoimmunity, Evolving Factors on Efficacy and Dosing and Challenges on Stopping Chronic IVIg TherapyCurrent Perspectives Published on 2021-11-112022-10-30 Journal: Neurotherapeutics : the journal of the American So [Category] Coronavirus, MERS, SARS, [키워드] Activation addressed affecting Anti-inflammatory effects anti-SARS-CoV-2 antibodies antibody antigenic peptides approved autoantibodies Autoimmune challenge chronic complement conditions conserved cross-react Cytokines Dosing Effect effective Efficacy Encephalitis epilepsy Evidence exhibit Express Factor fatigue FcγRIIb genes encoding Genetic healthy donors Humoral immunity IgG IgG1 Immunomodulation by IVIg Inflammatory mediators infused Initiating and stopping IVIg Intravenous immunoglobulin isotype IVIG IVIg and IgG4 neuro-autoimmunities MMN neurological Neurological disorders neurological sign neuronal pathogenic autoantibody Patient polymorphism positive Protein Randomized controlled trials recent receptors sera stability Stopping Symptom therapy Treatment weakness worsening [DOI] 10.1007/s13311-021-01108-4 PMC 바로가기 [Article Type] Current Perspectives