Obesity as an adipose tissue dysfunction disease and a risk factor for infections – Covid-19 as a case studyReview Article Published on 2021-04-022023-06-15 Journal: European journal of internal medicine [Category] MERS, SARS, [키워드] adipokines adiponectin ARDS Bariatric surgery COVID-19 Cytokine storm Diabetes Mellitus hypertension Leptin Mortality obesity SARS-CoV-2 [DOI] 10.1016/j.ejim.2021.03.031 PMC 바로가기 [Article Type] Review Article
Susceptibility and Severity of Viral Infections in Obesity: Lessons from Influenza to COVID-19. Does Leptin Play a Role?Review Published on 2021-03-202022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] adaptive immune system adipose approach association blunt Cell chronic complications Concentration concerning contribute Control COVID-19 determinant dysregulation Effect Effectiveness energy balance energy metabolism ER stress expressed Factors immune immune response immune system impair impairment Infection Infectious disease Inflammation inflammatory state Influenza influenza epidemic Interaction Leptin leptin resistance lesson mechanism metabolic microenvironment Multiple obesity outcome overcome pandemic Physical inactivity pleiotropic produced receptor reduced Regulatory Research responsible SARS-CoV2 severity Signaling Surveillance susceptibility tissue Vaccine vaccine-induced immune responses viral infection viral infections [DOI] 10.3390/ijms22063183 PMC 바로가기 [Article Type] Review
Obesity, Nutrients and the Immune System in the Era of COVID-19Review Published on 2021-02-132022-10-31 Journal: Nutrients [Category] COVID-19, MERS, [키워드] acute respiratory distress addition adipocyte adipocytes adipose Affect alteration Apoptosis cardiovascular complications caused characteristic chronic disease circulation complications Compound COVID-19 cytokine Cytokines death decrease disrupting Disseminated intravascular coagulation Effects element endothelial Endothelial dysfunction Endotheliitis excess Excessive activation fat Fat mass forms function hypercoagulability hypertrophic Immune cell immune cells immune system increase increase in induce Infection infection-related mortality Infectious complications infiltration Inflammasome Inflammation inflammatory state insulin resistance Leptin Lipid Lymphoid Organ Macrophage multiple organ failure NLRP3 inflammasome nutrient obese obesity pro-inflammatory promote recruitment released responsible risk risk factor risk of infection SARS-COV-2 infection saturated secondary bacterial infection severe complication severe COVID-19 Severe infection Shock shown subjects sugar susceptibility syndrome System systemic inflammatory These cells tissue [DOI] 10.3390/nu13020610 PMC 바로가기 [Article Type] Review
The effects of allium sativum on immunity within the scope of COVID-19 infection코로나19 감염 범위 내에서 부추속이 면역력에 미치는 영향Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 치료기술, [키워드] abnormality activated active against Acute respiratory infection adipose Adipose tissue Allium allium sativum antiinflammatory antimicrobial antiviral efficiency appear Appetite Asymptomatic disease boost characteristic Compound Concentration coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Cytokines decrease Decreased demonstrated dry cough dysfunction Dyspnea Effect expression fatigue Features functional functional food Garlic Gustatory helper helper T cells immune system immune system cell immune system cells Immune system dysfunction Immunity immunological immunomodulatory infected with SARS-CoV-2 Infection Leptin loss of appetite macrophages manifestation Manifestations Monocytes monocytes/macrophage monocytes/macrophages myalgia natural Natural killer cells olfactory parameters patients with COVID-19 prevalent preventive measure proinflammatory Proinflammatory cytokine proinflammatory cytokines Protein protein kinase protozoan parasites receptor regulatory T cells repress SARS-CoV-2 virus secretion severity suggested suppressed Symptom Symptoms T cells T lymphocytes tissue virus [DOI] 10.1016/j.mehy.2020.109934 PMC 바로가기 [Article Type] Article
Leptin levels in SARS-CoV-2 infection related respiratory failure: A cross-sectional study and a pathophysiological framework on the role of fat tissueArticle Published on 2020-08-202022-10-31 Journal: Heliyon [Category] COVID-19, [키워드] ACE2 activated ARDS BMI chronic inflammation clinical observations Control control patient control patients COVID-19 Critical care Critically ill cross cross-sectional Deterioration develop ENhance explain fat increase in Intensive care medicine Leptin Local lung lung tissue mechanical ventilation Microbiology non-infected obese patients pathophysiological produced pulmonary inflammation receptor Research respiratory Respiratory failure Respiratory system risk factor SARS-CoV-2 SARS-CoV-2 infected patient SARS-COV-2 infection serum significantly higher tissue Treatment ventilated patient Virology virus visceral was performed [DOI] 10.1016/j.heliyon.2020.e04696 PMC 바로가기 [Article Type] Article
Overnutrition in Infants Is Associated With High Level of Leptin, Viral Coinfection and Increased Severity of Respiratory Infections: A Cross-Sectional StudyOriginal Research Published on 2020-02-182023-08-30 Journal: Frontiers in Pediatrics [Category] E형 간염, [키워드] children Leptin overnutrition severity viral coinfection viral respiratory infection [DOI] 10.3389/fped.2020.00044 PMC 바로가기 [Article Type] Original Research
Immunity to influenza: Impact of obesityReview Published on 2019-09-012023-06-24 Journal: Obesity research & clinical practice [Category] 신종인플루엔자, [키워드] Influenza A/pdmH1N1 virus Leptin obesity Vaccine [DOI] 10.1016/j.orcp.2019.05.003 [Article Type] Review
Leptin signaling impairs macrophage defenses against Salmonella Typhimurium렙틴 신호전달은 대식세포의 살모넬라 타이피무리움에 대한 방어력을 저하시킨다.Article Published on 2019-08-132024-08-21 Journal: Microbial Cell Factories [Category] 살모넬라증, [키워드] AKT Leptin Lysosomes macrophages Salmonella
Serum leptin and homeostasis model assessment-IR as novel predictors of early liver fibrosis in chronic hepatitis B virus infectionArticle Published on 2018-10-012023-06-18 Journal: British journal of biomedical science [Category] B형 간염, [키워드] Hepatitis B virus homeostasis model assessment–IR Leptin Liver fibrosis [DOI] 10.1080/09674845.2018.1505187
Plasma Adiponectin and Hepatocellular Carcinoma Survival Among Patients Without Liver TransplantationArticle Published on 2016-10-012023-06-19 Journal: Anticancer research [Category] B형 간염, [키워드] adiponectin HCC Leptin Liver transplantation survival [DOI] 10.21873/anticanres.11103 PMC 바로가기