Success Rate of Wire Control-Assisted ERCP Sphincterotomy Versus Non-assisted ERCP Cannulation of Common Bile Duct in a Secondary Care Unit During the First COVID-19 Peak: A Retrospective Observational Study of 281 PatientsGastroenterology Published on 2021-09-092022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Analysis Anesthesia bile BSG Cannulation Chicago common common bile duct (cbd) Complication conducted correlation coefficient COVID 19 COVID-19 COVID-19 outbreak COVID-19 pandemic duct endoscopy ercp expected Factor First wave hospitals indication Infirmary insertion liver dysfunction Local logistic regression model National non-assisted ercp Obstructive outcomes pathology Patient performed predictor proportion Rate Result Science secondary selection process Significance significantly higher Society Spearman sphincterotomy SPSS Statistical Package statistically statistically significant statistically significant difference two-sided unit USA was performed was used window Wire wire control-assisted ercp [DOI] 10.7759/cureus.17861 PMC 바로가기 [Article Type] Gastroenterology
The Associations of Lymphocyte Ratio and Neutrophil Ratio on Liver Dysfunction in COVID-19 PatientsCOVID-19 환자의 간 기능 장애에 대한 림프구 비율과 호중구 비율의 연관성Immunology Published on 2021-09-062022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] adjusted Admission age Analysis association AST baseline blood sample Blood samples BMI China COVID-19 COVID-19 patient COVID-19 patients Cutoff determined by group groups Hospitalized IMPROVE incidence increased risk Inflammation Kaplan–Meier liver dysfunction liver dysfunctions Liver function lymphocyte Lymphocytes magnitude management Mild moderate neutrophil Neutrophils Occurrence over Patient patients Predictive Predictive value Ratio reflect Sex significant difference significant differences subsequent tested the patient threshold [DOI] 10.3389/fimmu.2021.717461 PMC 바로가기 [Article Type] Immunology
Impact of Recent SARS-CoV-2 Infection on the Course and Severity of Dengue in Children: A Prospective Observational Study from North India최근 SARS-COV-2 감염의 영향에 미치는 과정과 어린이의 뎅기열의 심각성 : 북인도의 전향 적 관찰 연구Observational Study Published on 2021-09-022022-09-10 Journal: The American Journal of Tropical Medicine and Hygi [Category] MERS, SARS, 임상, 치료기술, [키워드] abdominal pain Acute kidney injury Antibody Response antigenic assessment Chain Reaction children Clinical severity Course COVID-19 pandemic cross-protective death Dengue Dengue fever Diagnosis dysfunction edema ELISA enrolled evaluate the effect Evidence evidence of exposure to Features Frequency hepatomegaly IgG IgG antibody Impact incidence India infection with SARS-CoV-2 intensive care interquartile range invasive ventilation Laboratory laboratory diagnosis less liver dysfunction median median age North occurred organ dysfunctions outcome overlap pediatric preliminary evidence Prospective recent SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 SARS-CoV2 infection severe dengue Shock similarity study cohort Transmission virus viruses vomiting was done [DOI] 10.4269/ajtmh.21-0586 PMC 바로가기 [Article Type] Observational Study
Remdesivir in the COVID-19 Pandemic: An Analysis of Spontaneous Reports in VigiBase During 2020COVID-19 팬데믹에서의 렘데시비르: 2020년 동안 VigiBase의 자발적 보고서 분석Article Published on 2021-09-012022-09-11 Journal: Drug safety [Category] SARS, 진단, 치료제, [키워드] ADR ADRS Adverse drug reaction Adverse drug reactions Algorithm America Americas Analysis approved bradycardia collected comparator COVID-19 death demographics described Descriptive analysis Descriptive statistics disease effective indicated individual information Kidney injury liver dysfunction majority males median age Medicine Medicines Patient peaked Remdesivir report reported Retrieval Safety safety profile severity Spontaneous suggested Symptom the WHO Tocilizumab Treatment were used [DOI] 10.1007/s40264-021-01091-x PMC 바로가기 [Article Type] Article
Jaundice in patients with COVID ‐19Original Article Published on 2021-08-242022-10-29 Journal: JGH Open: An Open Access Journal of Gastroenterology and Hepatology [Category] COVID-19, [키워드] activities addressed Admission alanine aminotransferase alkaline phosphatase analyzed Bilirubin Care characterized clinical consequence Clinical features Concentration coronavirus disease COVID COVID‐19 COVID‐19 defined determine elevated etiology Fever Frequency hallmark hepatic Hepatitis hepatocellular high mortality Hospitalized Hypoxemia Injury intensive care Invasive mechanical ventilation jaundice laboratory abnormalities Leukocytosis leukopenia liver liver dysfunction Liver injury mortality rate Patient procalcitonin reported Result Sepsis serum serum creatinine severe acute respiratory syndrome coronavirus 2 significantly higher survival systemic inflammation total bilirubin while [DOI] 10.1002/jgh3.12645 PMC 바로가기 [Article Type] Original Article
Proinflammatory and Hepatic Features Related to Morbidity and Fatal Outcomes in COVID-19 PatientsArticle Published on 2021-07-152022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age association AST/ALT C-reactive protein CCI Charlson Comorbidity Index Clinical management Cohort Comorbidities concerning COVID-19 COVID-19 patients COVID-19 positive patient CRP D-dimer death determinant disease disease severity explain explained facilitate feature FIB-4 hepatic hospital hyperinflammation ICU IMPROVE Inflammation Inflammatory intensive care Interaction liver liver dysfunction liver markers marker median value morbidity Mortality neutrophil Neutrophils outcome outcomes oxygen saturation Personalized medicine Platelet Predictive proinflammatory Regression model Research ROC ROC Curve Sex therapy [DOI] 10.3390/jcm10143112 PMC 바로가기 [Article Type] Article
Use of Antioxidants for the Neuro-Therapeutic Management of COVID-19Review Published on 2021-06-172022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] Acute kidney injury addition adjuvant Ageusia analyzed Anosmia anti-vascular antioxidant antioxidants brain tissue cause caused cellular Central nervous system change clinical manifestation Complication contribute coronavirus 2 cough CoV infection COVID-19 death disease disorders distress drugs endothelial fatigue Fever Growth factors headache immunomodulators Infectious disease Inflammation Injury liver dysfunction modulating myalgias neuro-therapeutic management Neuroinvasive Neurological complication neurological damage neurological manifestation Neurological symptom oxidative stress respiratory SARS-CoV-2 Seizures specific treatment suggested Supportive treatment Symptom syndrome the disease Treatment Vaccine with COVID-19 [DOI] 10.3390/antiox10060971 PMC 바로가기 [Article Type] Review
Decreased Low-Density Lipoprotein Cholesterol Level Indicates Poor Prognosis of Severe and Critical COVID-19 Patients: A Retrospective, Single-Center StudyMedicine Published on 2021-05-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Acute cardiac injury Admission Analysis cardiac injury Characteristics Comorbidity Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients critical COVID-19 patient critical COVID-19 patients Critically ill patient CRP level death Decreased dysfunction dyslipidemia enrolled four group four groups global public health group Hospitalization ICU immune increased risk Inflammation Injury intensive care LDL-C Level lipoprotein liver dysfunction Low-density lipoprotein Low-Density Lipoprotein cholesterol Lymphocyte count mechanical ventilation Mortality not differ Patient Pearson correlation Poor poor prognosis positively correlated Prognosis proportion reduction renal dysfunction severe and critical COVID-19 patients severe patients Shock shown Symptom treated [DOI] 10.3389/fmed.2021.585851 PMC 바로가기 [Article Type] Medicine
Model of End-Stage Liver Disease (MELD) Score as a Predictor of In-Hospital Mortality in Patients with COVID-19: A Novel Approach to a Classic Scoring SystemInternal Medicine Published on 2021-05-222022-10-31 Journal: Cureus [Category] COVID-19, [키워드] age Asthma both group chronic heart failure Chronic kidney disease CKD classic clinical Cohort cohort study COVID-19 COVID-19 positive patient Dementia Diabetes Mellitus diagnosed with COVID-19 discharge evaluated greater group hospital Hospitalized hypertension ICU in-hospital mortality Infection Inflammation intensive care Limited Liver disease liver dysfunction LOS meld Model Mortality no significant difference novel Older outcome Patient predictor Prognosis Result risk score Scoring significantly higher stratified survival System viral infection with COVID-19 women [DOI] 10.7759/cureus.15179 PMC 바로가기 [Article Type] Internal Medicine
Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2 + Liver Progenitor Cells: Implications in Coronavirus Disease 2019-Associated Liver DysfunctionMedicine Published on 2021-04-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome analyzed angiotensin-converting enzyme 2 binding caused cell death cell population China cirrhotic liver co-expression Comorbidities coronavirus coronavirus disease COVID-19 COVID-19 patient Cytokine storms Deleterious develop disease fetal FIVE globe healthy host cell human liver impair implicated indicated liver Liver cirrhosis liver dysfunction liver tissue mammalian mammalian cell pandemic pathophysiology Patient prevalent progenitor Protein receptor reported respiratory symptom Respiratory virus infection RNA-Seq SARS-CoV-2 scRNA-seq serine protease significantly Single Cell single-cell RNA-seq spike the S protein tissue TMPRSS2 transmembrane serine protease Trop2 viral infection [DOI] 10.3389/fmed.2021.603374 PMC 바로가기 [Article Type] Medicine