PSCNN: PatchShuffle Convolutional Neural Network for COVID-19 Explainable DiagnosisPublic Health Published on 2021-10-292022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Accuracy backbone caused Convolutional neural network coronavirus COVID-19 COVID-19 diagnosis data augmentation deep learning develop Effectiveness grad-CAM Infectious disease introduced lung lesions MCC measure network Neural new strain overfitting PatchShuffle Precision sensitivity Seven specificity stochastic pooling Variation [DOI] 10.3389/fpubh.2021.768278 PMC 바로가기 [Article Type] Public Health
Subtle differences in the pathogenicity of SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in rhesus macaquesResearch Article Published on 2021-10-222022-10-28 Journal: Science Advances [Category] COVID-19, [키워드] absence animal B.1 B.1.1.7 B.1.351 bronchoalveolar can be used caused changes in chemokine circulation clinical disease confounding factors cytokine D614G description Efficacy favor immune evasion inoculated inoculation less lung lung lesions Medical countermeasures nasal samples pathogenicity phenotypical Replication respiratory tract rhesus rhesus macaque rhesus macaques SARS-CoV-2 SARS-CoV-2 variant severe disease Transmissibility up-regulated variants of concern virus titers VoC [DOI] 10.1126/sciadv.abj3627 PMC 바로가기 [Article Type] Research Article
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models세 가지 전임상 모델에서 COVA1-18 중화 항체가 SARS-CoV-2로부터 보호Article Published on 2021-10-202022-09-10 Journal: Nature Communications [Category] MERS, SARS, 변종, 신약개발, 유전자 메커니즘, 진단, 치료제, [키워드] acute respiratory syndrome coronavirus Administered animal model antibody antiviral activity B.1.1.7 B.1.1.7 isolate cause clinical evaluation coronavirus COVID-19 patients cynomolgus macaques Efficacy evaluate hACE2 hamsters High dose Immunotherapy in vivo Infectious diseases lung lung lesions Lungs lymphopenia macaque mathematical mathematical model mice monoclonal antibodies neutralizing antibody patients Preclinical research Prophylactic PROTECT reduce reduction in respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown therapeutic therapeutic effect Therapeutic treatment treated Treatment undetectable upper respiratory upper respiratory tract Viral viral infectivity Viral load viral loads [DOI] 10.1038/s41467-021-26354-0 PMC 바로가기 [Article Type] Article
CT-Based Radiomics Helps to Predict Residual Lung Lesions in COVID-19 Patients at Three Months after DischargeArticle Published on 2021-09-302022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Admission AUC build characteristic Chest CT image Combination coronavirus disease COVID-19 COVID-19 confirmed patient develop different time point discharge Effect Efficacy enrolled evaluate feature Follow-up help hospital Hospital admission lesion lung lung lesion lung lesions Month Patient Predictive Psychological Radiomics Randomly reduce Region residual residual lesion sensitivity specificity survivor Survivors tomography were used X-ray computed [DOI] 10.3390/diagnostics11101814 PMC 바로가기 [Article Type] Article
IgG Antibodies Develop to Spike but Not to the Nucleocapsid Viral Protein in Many Asymptomatic and Light COVID-19 CasesIgG 항체는 스파이크에 발달하지만 많은 무증상 및 가벼운 Covid-9 사례에서 Nucleocapsid 바이러스 단백질이 아닙니다.Article Published on 2021-09-282022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, 치료법, 치료제, [키워드] ACE-2 receptor anti-RBD Anti-RBD IgG antibody Antibody detection Asymptomatic Asymptomatic case Cohort cohort of patient conducted correlated COVID-19 detectable disease severity domain help IgG IgG antibodies IgG antibody immune response Indicator individual Infection inhibit Interaction LIGHT lung lesion lung lesions majority moderate nucleocapsid nucleocapsid protein Protein raise RBD Receptor-binding domain remained SARS-CoV-2 serum Serum Neutralization severe symptoms severity spike Spike protein Symptom the antibody the disease the RBD the spike protein Viral [DOI] 10.3390/v13101945 PMC 바로가기 [Article Type] Article
Case Report: Potential Role of Corticosteroids in the Management of Post-COVID-19 PneumoniaMedicine Published on 2021-09-092022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] accelerated activities acute respiratory distress Admission ARDS benefit characterized chest CT scan clinical symptom clinically complex coronavirus disease Corticosteroid corticosteroid therapy cough COVID-19 discharge discharged home dose Dyspnea Follow-up high-flow oxygen therapy Hospitalized immune reaction Inflammatory initial intensive care interstitial Interstitial lung diseases Lung disease lung lesions management Organizing pneumonia outcome oxygen Oxygen therapy Patient performed Pneumonia post-COVID-19 infection Potential pulmonary lesions required role SARS-CoV-2 PCR test Severe COVID-19 pneumonia severe pneumonia severity subject symptomatic symptomatic improvement syndrome the patient treated Withdrawal [DOI] 10.3389/fmed.2021.686806 PMC 바로가기 [Article Type] Medicine
Effect of COVID-19 on 18 F-FDG PET/CT: Is There a Need to Consider COVID-19 Status Before Planning 18 F-FDG PET/CT for Oncologic Evaluation?18 F-FDG PET/CT에 대한 COVID-19의 영향: 종양학적 평가를 위한 18 F-FDG PET/CT를 계획하기 전에 COVID-19 상태를 고려할 필요가 있습니까?Case Reports Published on 2021-09-012022-09-10 Journal: Journal of Nuclear Medicine Technology [Category] SARS, 치료기술, [키워드] 18F-FDG PET/CT Case report case reports Cell change coronavirus disease Coronavirus disease 2019 COVID-19 diagnosis of COVID-19 Effect help increasingly lung lung lesion lung lesions lung metastasis MOST oncology oncology patient oncology patients Patient PET/CT Planning renal renal cell carcinoma reported response evaluation retrospective retrospective diagnosis status [DOI] 10.2967/jnmt.121.262145 PMC 바로가기 [Article Type] Case Reports
Convalescent plasma is of limited clinical benefit in critically ill patients with coronavirus disease-2019: a cohort study회복기 혈장은 코로나바이러스 질병-2019가 있는 중환자에서 임상적 이점이 제한적입니다: 코호트 연구Research Published on 2021-08-262022-09-10 Journal: Journal of Translational Medicine [Category] MERS, SARS, 치료기술, [키워드] 28-day mortality Abstract Analysis analyzed benefit calculated Characteristics clinical clinical benefit Clinical characteristics clinical evidence clinically cohort study Comorbidity condition contribute control group convalescent plasma coronavirus coronavirus disease coronavirus disease-2019 Critically ill Critically ill patient critically ill patients cumulative cumulative mortality cumulative survival rate Data analysis dead debate disease evidence of Fever group Kaplan–Meier survival analysis late stage lung lesion lung lesions median age Mortality no significant difference not significant observation one patient outcome Patient patients receiving CP plasma radiological reported Result Safe safety profile SARS-CoV-2 significant difference standard treatment supplementary material survival analysis survival rate Transient was performed [DOI] 10.1186/s12967-021-03028-5 PMC 바로가기 [Article Type] Research
Quantitative CT for detecting COVID‑19 pneumonia in suspected cases의심되는 경우에서 Covid -19 폐렴을 검출하기위한 정량적 CTResearch Article Published on 2021-08-192022-09-01 Journal: BMC Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] analyzed artificial intelligence assist automatically auxiliary Chain Reaction characteristic Computed tomography consolidation Convolutional neural network Corona COVID-19 COVID-19 pneumonia COVID‐19 diagnosing diagnosis of COVID-19 diagnostic value effective excluded expected GGO Ground glass opacity Hounsfield unit Hounsfield units Infection lobe lobes lung lung lesions negative RT-PCR nine parameter Patient patients with COVID-19 PCR test Pneumonia polymerase chain polymerase chain reaction positive provide public health Quantification method Quantitative Quantitative CT receiver receiver operating characteristic Result reverse transcription right lung ROC RT-PCR RT-PCR test sensitivity specificity statistical difference statistical differences statistically supplementary material Suspected cases threshold Threshold segmentation thresholds to define two groups Virus Disease VoC Volume was used were used worldwide pandemic [DOI] 10.1186/s12879-021-06556-z PMC 바로가기 [Article Type] Research Article
Chest CT abnormalities in COVID-19: a systematic reviewCOVID-19의 흉부 CT 이상: 체계적인 검토Research Paper Published on 2021-08-012022-09-12 Journal: International Journal of Medical Sciences [Category] MERS, 진단, [키워드] abnormality Admission adopted approach association average blood cell Case report case sery Characteristics Chest Chest CT Clinical severity comorbid condition Computed tomography computed tomography (CT) consolidation coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) cough COVID-19 COVID-19 patient CT finding CT findings diabetes Diabetes Mellitus diagnostic Fever followed by GGO ground-glass opacity hypertension individuals Infection involved Laboratory lung lung lesion lung lesions lymphocyte meta-analyses MOST Most patient Most patients normal range Patient patients radiologic searched Symptom symptom onset systematic review systematic reviews tomography Vascular Web of Science White blood cell white blood cell count [DOI] 10.7150/ijms.50568 PMC 바로가기 [Article Type] Research Paper