SARS-CoV-2 RNAs are processed into 22-nt vsRNAs in Vero cellsArticle Published on 2022-10-282023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] IFN Immunity MicroRNAs SARS-CoV-2 virus-derived small RNAs. [DOI] 10.3389/fimmu.2022.1008084 PMC 바로가기
Neuropilin-1 in the pathogenesis of preeclampsia, HIV-1, and SARS-CoV-2 infection: A reviewReview Published on 2022-10-022023-07-10 Journal: Virus research [Category] COVID19(2023년), [키워드] HIV-1 infection MicroRNAs Neuropilin-1 preeclampsia SARS-COV-2 infection [DOI] 10.1016/j.virusres.2022.198880 PMC 바로가기 [Article Type] Review
Dysregulated miRNAs network in the critical COVID-19: An important clue for uncontrolled immunothrombosis/thromboinflammation중요한 COVID-19에서 조절되지 않는 miRNA 네트워크: 통제되지 않는 면역혈전증/혈전염증에 대한 중요한 단서Review Published on 2022-09-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] accompanied activated Activation adenine affecting anti-inflammatory factors Anticoagulant cause clinical complication Coagulation Coagulation system complement complement system Complication components conserved coronavirus disease Coronavirus disease 2019 COVID-19 Critical Cytokine storm Defensive mechanism deviation diffusion Effect expression expression level facilitate Factor function Genetic higher risk homeostasis hyperinflammation immune immunothrombosis incidence Interaction involved life-threatening mechanism microRNA MicroRNAs miRNA miRNAs miRNAs-based therapy. molecules Mortality NADPH nicotinamide nicotinamide adenine dinucleotide Nicotinamide adenine dinucleotide phosphate Non-coding RNAs nucleotide oxygen Pathogens Patient phosphate reactive oxygen species reactive oxygen specy reduction response restrict SARS-CoV-2 severe complications Therapeutic approach therapy Thromboinflammation thrombotic underlie vicious cycle [DOI] 10.1016/j.intimp.2022.109040 PMC 바로가기 [Article Type] Review
Plasma microRNA and metabolic changes associated with pediatric acute respiratory distress syndrome: a prospective cohort study Research Published on 2022-08-262022-10-05 Journal: Scientific Reports [Category] 바이오마커, [키워드] acute respiratory distress ARDS Bacterial infection Biomarker Biomarkers both groups change circulating circulation Clinical characteristics conducted control patient correlated Critically ill defined differential expression differentially expressed distress evaluate heterogeneous identify intensive care patients metabolite metabolomics microRNA MicroRNAs miRNA miRNA expression morbidity and mortality non-coding RNA pathophysiological Patient pediatric Pediatric patient Pediatric patients pilot study prognostic biomarker progression prospective cohort study provide Random forest random forest classification responsible risk selected single-center sub-cohort subset syndrome therapeutic intervention [DOI] 10.1038/s41598-022-15476-0 [Article Type] Research
Gene Network Analysis of the Transcriptome Impact of SARS-CoV-2 Interacting MicroRNAs in COVID-19 DiseaseCOVID-19 질병에서 SARS-CoV-2 상호작용 MicroRNA의 전사체 영향에 대한 유전자 네트워크 분석Review Published on 2022-08-172022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 유전자 메커니즘, [키워드] affected Analysis biochemical biological processes Cell cell cycle cell surface receptor changes characterized COVID-19 COVID-19 disease cytokine death DEGs differentially expressed differentially expressed gene Differentially expressed genes downregulated exploratory FIVE functional enrichment Functional enrichment analysis Gene Expression gene network Health Organization heart Impact involved kidneys list lung Lymph node microRNA MicroRNAs mitochondrial mitotic mitotic cell modulation molecular Multiorgan multiorgan disease network network analysis pathological mechanism Pathways Perspective predicted provide reported SARS-CoV-2 SARS-CoV-2 virus signaling pathway submitted surface receptor target tissue tissues transcriptomes translated upregulated WHO with COVID-19 World Health Organization [DOI] 10.3390/ijms23169239 PMC 바로가기 [Article Type] Review
Maternal vaccination as an additional approach to improve the protection of the nursling: Anti-infective properties of breast milkArticle Published on 2022-08-102022-11-15 Journal: Clinics [Category] 진단, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 vaccines antibody Antibody Response approach B lymphocyte bacterial antigen Bioactive factors Breast breast milk Breastfeeding chemokines complement component cytokine elevated Factors fatty acids function Growth factors hormone Human IgA IgA antibodies IgA antibody IgG antibody IMPROVE inactivated induce lactation lactoferrin leukocyte mammary Maternal maternal immunization MicroRNAs nucleic acids oligosaccharides pandemic passive immunity performed Placenta Plasma cell plethora polysaccharide Pregnancy produced Proteins respiratory infections respiratory tracts secretion secretory secretory IgA Secretory IgA antibodies. Specific specific antibody unique vaccination Vaccine Vaccines virus virus-neutralizing viruses [DOI] 10.1016/j.clinsp.2022.100093 PMC 바로가기
Identification of differentially expressed genes and their major pathways among the patient with COVID-19, cystic fibrosis, and chronic kidney diseaseResearch article Published on 2022-08-072022-10-05 Journal: Informatics in Medicine Unlocked [Category] 바이오마커, 변종, [키워드] analysed Analysis bioinformatics cause Chronic kidney disease CKD Comorbidity COVID-19 COVID-19 disease cystic fibrosis dataset differentially expressed gene Differentially expressed genes disease disease categories drug expression profiling fibrosis FOXN2 functional Gene regulatory networks help HNF4A identification identify indicated Infectious disease Interaction involved majority MicroRNAs Mild moderate Multiple Ontology pathophysiological pathway Patient patients with COVID-19 performed Potential biomarker predicted protein-protein interaction PRPF31 reducing regulated researcher respiratory symptoms RIOK3 SARS-CoV-2 SARS-CoV-2 virus System biology the patient therapeutic molecules transcription factor Transcriptomic profiling UBC upregulated upregulated genes virus was done with COVID-19 [DOI] 10.1016/j.imu.2022.101038 [Article Type] Research article
RNA solutions to treat inborn errors of metabolism신진대사의 선천적 오류를 치료하기 위한 RNA 솔루션Review Published on 2022-08-012022-09-11 Journal: Molecular genetics and metabolism [Category] 유전자 메커니즘, [키워드] activating antisense Antisense oligonucleotides approved Biology Chemistry Clinical efficacy clinical trial clinical trials Clinical use COVID-19 drug drugs effective expression gene silencing help IEM include lncRNA mechanism mechanism of action messenger RNAs metabolism MicroRNAs molecules mRNA mutations New offer overcome Patient pharmacokinetic rare disease rare diseases Research RNA RNA interference RNA vaccine RNA vaccines RNAs siRNA splicing Stage suppress target tissues Therapeutic approach therapy tissues treat [DOI] 10.1016/j.ymgme.2022.07.006 PMC 바로가기 [Article Type] Review
The emerging role of miRNAs in the pathogenesis of COVID-19: Protective effects of nutraceutical polyphenolic compounds against SARS-CoV-2 infectionCOVID-19의 발병기전에서 miRNA의 새로운 역할: SARS-CoV-2 감염에 대한 기능식품 폴리페놀 화합물의 보호 효과Review Published on 2022-07-182022-09-11 Journal: International Journal of Medical Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] accumulating acting acute respiratory syndrome acute respiratory syndrome coronavirus anti-SARS-CoV-2 attenuate Clinical efficacy Compound coronavirus coronavirus 2 Coronaviruses COVID-19 Cytokine storm death Diagnosis diagnostic drug Effect Evidence expression Host host cell host cells immune response Immunosuppression implication Infection life cycle lung damage MicroRNAs miRNA miRNA expression miRNAs modulating outcome Pathogenesis patients with SARS-CoV-2 prognostic biomarker Prognostic biomarkers PROTECT protein-coding genes RNA RNA transcript SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection SARS-CoV-2 replication Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Treatment treatment of COVID-19 viral entry viral replication [DOI] 10.7150/ijms.76168 PMC 바로가기 [Article Type] Review
Identification of Liver and Plasma microRNAs in Chronic Hepatitis B Virus infectionArticle Published on 2022-06-022023-06-13 Journal: Frontiers in Cellular and Infection Microbiology [Category] B형 간염, [키워드] Biomarkers Hepatitis B virus MicroRNAs next generation sequencing novel therapy targets. [DOI] 10.3389/fcimb.2022.790964 PMC 바로가기