An ELISA system for tetanus toxoid potency tests: An alternative to lethal challengearticle Published on 2023-05-312024-09-01 Journal: Biologicals [Category] 파상풍, [키워드] 3Rs ELISA Lethal challenge mouse neutralization tetanus toxoid [Article Type] article
Oral Administration of Universal Bacterium-Vectored Nucleocapsid-Expressing COVID-19 Vaccine is Efficacious in Hamstersarticle Published on 2023-03-142024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] bacterial vector COVID-19 membrane protein mouse nucleocapsid protein oral administration Oral vaccine SARS-CoV-2 single vector platform single vector platform vaccine Syrian hamster Vaccine vaccine vector [DOI] 10.1128/spectrum.05035-22 PMC 바로가기 [Article Type] article
Of Murines and Humans: Modeling Persistent Powassan Disease in C57BL/6 MiceResearch Article Published on 2023-02-212024-09-05 Journal: mBio [Category] update2024, [키워드] animal model chronic deer tick virus Encephalitis flavivirus in vivo Inflammation Meningitis mouse Powassan virus tick-borne infection [DOI] 10.1128/mbio.03606-22 PMC 바로가기 [Article Type] Research Article
The gut microbiome in Alzheimer’s disease: what we know and what remains to be exploredarticle Published on 2023-02-012024-09-05 Journal: Molecular Neurodegeneration [Category] update2024, [키워드] amyloid diet exercise gut microbiome Human mouse Neuroinflammation Peripheral immunity Sleep Tau Therapeutics [DOI] 10.1186/s13024-023-00595-7 PMC 바로가기 [Article Type] article
Proteomics Profiling Reveals Regulation of Immune Response to Salmonella enterica Serovar Typhimurium Infection in Mice단백질체 프로파일링은 쥐에서 살모넬라 엔테리카 세로바르 타이피무리움 감염에 대한 면역 반응의 조절을 밝혀냅니다.Article Published on 2023-01-242024-08-22 Journal: Infection and Immunity [Category] 살모넬라증, [키워드] genetic regulation immune response mass spectrometry mouse proteome proteomics S. Typhimurium Salmonella
Genetic mapping of determinants in drug resistance, virulence, disease susceptibility, and interaction of host-rodent malaria parasitesarticle Published on 2022-12-312024-09-01 Journal: Parasitology International [Category] 말라리아, [키워드] association Genotype linkage mouse phenotype Plasmodium [Article Type] article
The origins, isolation, and biological characterization of rodent malaria parasitesarticle Published on 2022-12-312024-09-01 Journal: Parasitology International [Category] 말라리아, [키워드] mouse Plasmodium berghei Plasmodium chabaudi Plasmodium vinckei Plasmodium yoelii RAT [Article Type] article
Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model마우스 모델에서 SARS-CoV-2 공격에 대한 보호 반응 유도에 대한 최적화된 서열과 SARS-CoV-2의 스파이크 단백질 야생형 DNA 서열의 비교Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 비임상, 진단, [키워드] acid Against Antiviral binding breath CD4 CD8+ cellular immune responses cellular immunity challenge clinical trial contributing to COVID-19 CTL demonstrated DNA DNA vaccine expression full-length spike protein hACE2 humoral humoral and cellular immunity IFN-γ immune immune responses immunogen in vitro induction mice Model mouse Neutralizing antibodies optimization optimizations pGX-9501 platform Protective Protective effects protective response RBD binding response robust SARS-CoV-2 sequence spike Spike protein subsequent T cell T cells the vaccine Transgenic mouse Type virus wild-type wild-type sequence. [DOI] 10.1080/21645515.2021.2016201 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Variant-Specific Infectivity and Immune Profiles Are Detectable in a Humanized Lung Mouse ModelArticle Published on 2022-10-162022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] animal model B.1.1.7 B.1.1.7 variant expected greater higher infectivity Human immune system human lung tissue humanized humanized mice immune cells Immune profile immune response Immunity Infection Infectivity lesion Lineage lung lung organoid mice Model mouse no difference overlapping Pathogenesis pathogenesis of SARS-CoV-2 profile replication of SARS-CoV-2 required Research SARS-CoV-2 SARS-COV-2 infection similarity Support supported sustained Th1 Th2 variant variants of concern Viral load viral variant Viral variants virus [DOI] 10.3390/v14102272 PMC 바로가기
The N501Y Mutation of SARS-CoV-2 Spike Protein Impairs Spindle Assembly in Mouse OocytesArticle Published on 2022-10-012022-11-16 Journal: Reproductive Sciences [Category] COVID19(2023년), SARS, 변종, [키워드] accompanied assembly caused control group COVID-19 pandemic demonstrated female functions Health impairment indicated Infection influence maturation mouse mutant mutant spike protein N501Y N501Y variant Oocyte Oocyte maturation oocytes potential risk Protein provided reproductive SARS-CoV-2 SARS-CoV-2 spike protein significantly increased spike Spike protein Spindle spindle assembly the mean [DOI] 10.1007/s43032-021-00809-7 PMC 바로가기