mRNA-based – Page 3 – Communicable Diseases Research

The clinical progress of mRNA vaccines and immunotherapies

Reviews

Published on 2022-05-092022-10-05
Journal: Nature biotechnology [Category] 임상,

The Current Landscape of mRNA Vaccines Against Viruses and Cancer-A Mini Review

바이러스 및 암에 대한 mRNA 백신의 현재 상황-A 미니 리뷰

Review

Published on 2022-05-062022-09-11
Journal: Frontiers in Immunology [Category] 유전자 메커니즘,

Vaccine protection against the SARS-CoV-2 Omicron variant in macaques

원숭이의 SARS-CoV-2 오미크론 변종에 대한 백신 보호

Article

Published on 2022-04-282022-09-11
Journal: Cell [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] Ad26 Ad26.COV2.S Ad26.COV2.S vaccine Adenovirus antibody Antibody titer Antibody titers B.1.1.529 BNT162b2 BNT162b2 vaccine Bronchoalveolar lavage CD8+ T cell Cellular immune response contribute correlated cynomolgus macaques demonstrated Efficacy heterologous prime-boost High-dose homologous humoral immune responses macaque macaque. moderate mRNA mRNA-based mutated nasal swabs neutralizing antibody titers omicron populations question raised regimen respiratory response robust SARS-CoV-2 SARS-CoV-2 variant Spread T cell T cell responses the SARS-CoV-2 These data undetectable upper respiratory tract Vaccine Vaccines variant virus
[DOI] 10.1016/j.cell.2022.03.024 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Spike S1-specific IgG kinetic profiles following mRNA or vector-based vaccination in the general Dutch population show distinct kinetics

일반 네덜란드 인구에서 mRNA 또는 벡터 기반 백신 접종 후 SARS-CoV-2 스파이크 S1 특이적 IgG 역학 프로파일은 뚜렷한 역학을 보여줍니다

Article

Published on 2022-04-082022-09-12
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단,

Potential Immunogenic Activity of Computationally Designed mRNA- and Peptide-Based Prophylactic Vaccines against MERS, SARS-CoV, and SARS-CoV-2: A Reverse Vaccinology Approach

MERS, SARS-CoV 및 SARS-CoV-2에 대한 계산적으로 설계된 mRNA 및 펩티드 기반 예방 백신의 잠재적 면역원 활성: 역백신학 접근

Article

Published on 2022-04-062022-09-11
Journal: Molecules [Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] 3D structure activity acute respiratory syndrome coronavirus antiviral therapeutics B-cells binding coronavirus Coronavirus-2 Coronaviruses cross-protective CTL CTLs cytotoxic cytotoxic T lymphocytes develop effective Efficacy epitope Epitope-based vaccine Epitopes evaluated followed by HCoVs helper highly pathogenic HTL epitope HTL epitopes HTLs human coronavirus human coronaviruses humans Immune simulation immunogenic immunogenic activity imperative lethality MERS MERS-CoV Middle East Middle East respiratory syndrome Coronavirus molecular docking mRNA mRNA-based offer pandemic pathogenic coronaviruses peptide Potential predicted processed Prophylactic prophylactic vaccine. proteomic RBDs receptor-binding domains respiratory respiratory syndrome coronavirus SARS-CoV SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 similarity the receptor-binding domain these viruses TLR4 Vaccine Vaccine design viruses
[DOI] 10.3390/molecules27072375 PMC 바로가기 [Article Type] Article

First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction

Pfizer-BioNTech mRNA COVID-19 백신(BNT162b2, Comirnaty)의 초기 투여 후 치명적인 전격성 괴사성 호산구성 심근염의 첫 번째 확인된 사례: 극히 드문 특발성 과민 반응

Case Reports

Published on 2022-04-012022-09-12
Journal: Journal of Clinical Immunology [Category] 진단,

Neutralization of SARS-CoV-2 Variants by mRNA and Adenoviral Vector Vaccine-Elicited Antibodies

mRNA 및 아데노바이러스 벡터 백신 유도 항체에 의한 SARS-CoV-2 변이체의 중화

Article

Published on 2022-03-082022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단,

The indirect effect of mRNA-based COVID-19 vaccination on healthcare workers’ unvaccinated household members

Observational Study

Published on 2022-03-042022-10-05
Journal: Nature Communications [Category] SARS, 임상, 치료법,

Incidence of Cerebral Venous Thrombosis Following SARS-CoV-2 Infection vs mRNA SARS-CoV-2 Vaccination in Singapore

Observational Study

Published on 2022-03-012022-10-04
Journal: JAMA Network Open [Category] SARS, 임상,

[키워드] 95% CI age BNT162b2 caused cerebral Characteristics clinical Clinical characteristics conducted diagnosed dose hospital Hospitalization immunisation incidence incidence rate individual Infection male median Messenger RNA Moderna mRNA mRNA-1273 mRNA-based mRNA-based SARS-CoV-2 vaccines Observational cohort study occur outcome patients hospitalized Perspective Pfizer-BioNTech positive serology Quantitative registry remained report SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly higher Singapore the median vaccination Vaccine Venous thrombosis
[DOI] 10.1001/jamanetworkopen.2022.2940 PMC 바로가기 [Article Type] Observational Study

Immunogenicity and reactogenicity of homologous mRNA-based and vector-based SARS-CoV-2 vaccine regimens in patients receiving maintenance dialysis

유지 투석을 받는 환자에서 상동 mRNA 기반 및 벡터 기반 SARS-CoV-2 백신 요법의 면역원성과 반응성

Article

Published on 2022-03-012022-09-12
Journal: Clinical immunology (Orlando, Fla.) [Category] COVID19(2023년), MERS, SARS, 진단,