COVID-19: High-JAKing of the Inflammatory “Flight” by Ruxolitinib to Avoid the Cytokine Storm
Oncology
[키워드] Activation
admitted to ICU
approach
approved
CAR-T
caused
COVID-19
COVID-19 mortality
COVID-19 patient
CRS
cytokine
cytokine release
deleterious effect
dendritic cells
evaluated
events
ferritin
fibrosis
graft-versus-host-disease
hematologic
hematological
high mortality
HLH
Hospitalization
hyperinflammation
ICU
IL-6
immune-cell
Immunotherapy
impacted
IMPROVE
Italy
Jak
JAK1
JAK2
janus
kinase
limit
lymphocyte
Macrophage
management
Migration
molecular
molecular mechanism
multi-organ failure
myelofibrosis
outbreak
outcome
overcome
pathogenic
Patient
Proinflammatory cytokine
reducing
Respiratory failure
ruxolitinib
SARS-CoV-2
selective
Signaling
solid tumor
storm
syndrome
tissue damage
TNFα
treated
Treatment
turn
virus
[DOI] 10.3389/fonc.2020.599502 PMC 바로가기 [Article Type] Oncology
[DOI] 10.3389/fonc.2020.599502 PMC 바로가기 [Article Type] Oncology