myocardial damage – Page 3 – Communicable Diseases Research

Multisystem Inflammatory Syndrome Following SARS-CoV-2 Infection in Children: One Year after the Onset of the Pandemic in a High-Incidence Area

Article

Published on 2021-10-072022-10-28
Journal: Viruses [Category] COVID-19, MERS, SARS,

Characterization of myocardial injury in a cohort of patients with SARS-CoV-2 infection

SARS-CoV-2 감염 환자 집단에서 심근 손상의 특성화

Article

Published on 2021-09-242022-09-11
Journal: Medicina clínica [Category] SARS, 바이오마커,

[키워드] age Arrhythmias bleeding bleeding events characterization chronic clinical outcomes Cohort cohort of patient complications concentrations consecutive patients covariates COVID-19 criteria Daño miocárdico death died Elevation English European Follow-up Future heart failure hs-TNI IMPROVE independent Infection Injury limitations male mechanical ventilation median Mild Mortalidad Mortality myocardial damage myocardial injury onset of symptom outcomes overcome Patient patients with COVID-19 patients with SARS-CoV-2 prevalent Prognosis prognostic Pronóstico Research Resultados SARS-COV-2 infection significantly significantly more Sin Spanish Stratification thrombotic time troponin troponin I Troponina
[DOI] 10.1016/j.medcli.2021.02.001 PMC 바로가기 [Article Type] Article

Myocardial Damage by SARS-CoV-2: Emerging Mechanisms and Therapies

SARS-COV-2에 의한 심근 손상 : 신흥 메커니즘 및 요법

Review

Published on 2021-09-212022-09-01
Journal: Viruses [Category] SARS, 유전자 메커니즘, 진단, 치료법,

[키워드] acting action potential acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Apoptosis arrhythmia ATP attack autophagy cause Cell cells coronavirus creating damage decrease direct infection docking drug early stage early stages Effect effective Endothelial cell endothelial cells energy energy metabolism evade heart host cell Host immune response Imbalance immune cells immune response immunosuppressive immunosuppressive therapy induce infect Inflammation inhibit ion homeostasis lead leads metabolism myocardial damage myocarditis necroptosis organ Potential treatment priming programmed cell death promote protease Protease inhibitor protease inhibitors Proteases pyroptosis receptor Replication respiratory RNA-dependent RNA polymerase ROS production SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus ssRNA stages therapy treatment of viral infection turn Vesicle Viral viral clearance viral docking viral entry viral replication viroporin
[DOI] 10.3390/v13091880 PMC 바로가기 [Article Type] Review

Tumor Necrosis Factor-Alpha Exacerbates Viral Entry in SARS-CoV2-Infected iPSC-Derived Cardiomyocytes

종양 괴사 인자-알파는 SARS-CoV2에 감염된 iPSC 유래 심근세포에서 바이러스 유입을 악화시킵니다

Article

Published on 2021-09-132022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 치료기술, 치료법,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggravate ameliorated Analysis angiotensin Bioinformatics analysis Cardiomyocytes cardiovascular system caused Cell coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine storm elevated enzyme expressed expression Genes host cells Impact in vitro indicated induce pluripotent stem cells Infection Inflammation Mortality Multi-organ damage myocardial damage neutralization pandemic platform Proinflammatory cytokine protease Protein pseudovirus receptor receptors respiratory SARS-CoV2 SARS-CoV2 infection SARS-CoV2 pseudovirus Serine severe acute respiratory syndrome Coronavirus significantly increased stem cell susceptibility the cytokine storm the viral nucleocapsid TMPRSS2 TNF-α TNF-α TNF-α expression transmembrane Tumor tumor necrosis tumor necrosis factor-α turn upregulate Viral viral entry
[DOI] 10.3390/ijms22189869 PMC 바로가기 [Article Type] Article

COVID-19 and Acute Coronary Syndromes: From Pathophysiology to Clinical Perspectives

Review Article

Published on 2021-08-302022-10-29
Journal: Oxidative Medicine and Cellular Longevity [Category] COVID-19, MERS, SARS,

[키워드] addition Affect aggregation Anemia atherosclerotic plaque cardiovascular risk cellular damage clinical Clinical course condition Coronary coronary syndrome coronavirus disease COVID-19 COVID-19 patient decrease described Effect Endothelial cell Endothelial dysfunction expression generate Hyperinflammatory hypoxic induce Injury Local Logistic management Microvascular thrombosis Mortality myocardial damage Myocardial infarction oxidative stress oxygen oxygen supply Pathogenesis pathophysiology Patient Perspective Platelet platelets count potential mechanism promote Prothrombin time prothrombotic prothrombotic state reflect reported Research Sepsis severe disease Shock subject superoxide anions systemic inflammatory response therapeutic thrombus formation tissue type 1 MI von Willebrand factor with COVID-19
[DOI] 10.1155/2021/4936571 PMC 바로가기 [Article Type] Review Article

Peculiaridade dos Pacientes com Arritmias Hereditárias na Pandemia pela COVID-19

Artigo de Revisão

Published on 2021-08-092022-10-28
Journal: Arquivos Brasileiros de Cardiologia [Category] COVID-19, MERS, SARS,

[키워드] Aarrhythmogenic Right Ventricular Cardiomyopathy acute respiratory syndrome Arrhythmias Brugada syndrome Cardiomiopatia Arritmogênica do Ventrículo Direito Cardiomyopathy Catecholaminergic polymorphic ventricular tachycardia caused Clinical course COVID-19 Diseases Drug interactions electrolyte disturbances exacerbate Factors Fever hidden highlight infecção infectious condition Long QT syndrome myocardial damage New coronavirus Pandemia pandemic Patient pelo coronavírus Prevalence respiratory infection Síndrome de Brugada Síndrome do QT Longo SARS-CoV-2 Stress syndrome Tachycardia Taquicardia Ventricular Polimórfica Catecolaminérgica ventricular
[DOI] 10.36660/abc.20200391 PMC 바로가기 [Article Type] Artigo de Revisão

Right Ventricular Strain Is Common in Intubated COVID-19 Patients and Does Not Reflect Severity of Respiratory Illness

우심실 긴장은 삽관된 COVID-19 환자에서 흔하며 호흡기 질환의 중증도를 반영하지 않습니다

Article

Published on 2021-08-012022-09-11
Journal: Journal of Intensive Care Medicine [Category] 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome Affect age airway alveolar Analysis Atelectasis Biomarkers cardiac dysfunction chest imaging common comorbid conditions coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients demographics determine develop disease severity dysfunction echocardiographic had more hypoxic illness induce Inflammation inflammatory markers investigated Laboratory Lung compliance Lung disease lung mechanics mechanical ventilation mechanically ventilated mechanically ventilated COVID-19 patients medical record medications myocardial damage myocarditis Non-COVID-19 non-COVID-19 acute respiratory distress syndrome outcome Oxygenation pathogenic mechanism pathology Patient Plateau pressure Pulmonary embolism quantified receiving reduced respiratory respiratory distress Respiratory distress syndrome Respiratory failure right right ventricle Right ventricular RV dysfunction secondary to serum troponin severity strain syndrome thrombosis Tidal volume vasoconstriction vasopressor requirements Ventilation ventilatory ventilatory parameters ventricular Volume
[DOI] 10.1177/08850666211006335 PMC 바로가기 [Article Type] Article

SARS-CoV-2, myocardial injury and inflammation: insights from a large clinical and autopsy study

SARS-CoV-2, 심근 손상 및 염증: 대규모 임상 및 부검 연구에서 얻은 통찰력

Original Paper

Published on 2021-07-192022-09-11
Journal: Clinical Research in Cardiology [Category] MERS, SARS, 유전자 메커니즘, 치료기술,

[키워드] Abstract age analyzed Antigen association Autopsy autopsy study Cardiac autopsy study characterized chronic clinical Clinical data Cohort Comorbidities Comorbidity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 patients Deceased disease Evidence evidence of First wave form histological analysis Hospitalized immunohistochemistry Infection Inflammatory Injury lung Lungs mechanism Myocardial myocardial damage Myocardial inflammation myocardial injury myocarditis Necrosis objective pandemic Patient patients recorded Result RNA RT-PCR SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection SARS-CoV-2 viral severe SARS severe SARS-CoV-2 severity of COVID-19 supplementary material the patient tissue Viral viral antigens viral genomes viral persistence
[DOI] 10.1007/s00392-021-01910-2 PMC 바로가기 [Article Type] Original Paper

Identification of Causal Genes of COVID-19 Using the SMR Method

Genetics

Published on 2021-07-052022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

T2-mapping increase is the prevalent imaging biomarker of myocardial involvement in active COVID-19: a Cardiovascular Magnetic Resonance study

T2 매핑 증가는 활성 COVID-19에서 심근 관련의 일반적인 이미징 바이오마커입니다: 심혈관 자기 공명 연구

Observational Study

Published on 2021-06-102022-09-10
Journal: Journal of Cardiovascular Magnetic Resonance [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제,

[키워드] Abnormalities abnormality active phase Artery Biomarker cardiovascular Cardiovascular Magnetic Resonance change characterization clinical Cohort collected Comparisons control group Coronary arteries coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 diagnosis COVID-19 patients cTnT decrease Diagnosis disease Early detection edematous enrolled Evidence evidence of Extracellular fraction gadolinium healthy control healthy controls in vivo individual individuals Infection Inflammation IQR Laboratory laboratory characteristics laboratory findings linear correlation median moderate Myocardial myocardial damage Myocardial infarction myocardial injury myocardial involvement myocarditis Observational cohort study Occurrence parameters Patient patients Pericarditis positive linear correlation positively correlated predominant prevalent protocol Quantitative imaging referred to relationship resonance Result retrospective risk risk factor SARS-CoV-2 selected sensitivity Sex supplementary material Symptomatic treatment time interval tissue troponin troponin T Volume volume fraction
[DOI] 10.1186/s12968-021-00764-x PMC 바로가기 [Article Type] Observational Study