Application of the amplification-free SERS-based CRISPR/Cas12a platform in the identification of SARS-CoV-2 from clinical samplesResearch Published on 2021-09-082022-10-29 Journal: Journal of Nanobiotechnology [Category] COVID-19, SARS, [키워드] amplification application biosensors Cas12a clinical sample contagious COVID-19 CRISPR described diagnostic disease identify nasopharyngeal swab specimen nucleic acid nucleic acids performed platform POCT point of care polymerase chain Quantitative rapid diagnostic assay reverse transcription RNA RNA extract RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA sensitivity Sensitivity and specificity Sliver nanoparticle supplementary material Surface-enhanced Raman scattering [DOI] 10.1186/s12951-021-01021-0 PMC 바로가기 [Article Type] Research
Evaluating the Effect of a Modified Sample Preparation on SARS-CoV-2 Detection in a Cartridge-Based Platform카트리지 기반 플랫폼에서 SARS-CoV-2 검출에 대한 변형된 샘플 준비의 효과 평가Article Published on 2021-09-012022-09-11 Journal: The journal of applied laboratory medicine [Category] SARS, 치료기술, [키워드] Accuracy analytical sensitivity cartridge Ct value cycle threshold defined detection Device dramatic increase Effect eliminated eliminating Elimination Emergency use authorization ePlex system EUA evaluate Evaluating IMPROVE limit of detection medium Modification nasopharyngeal Nasopharyngeal swab nasopharyngeal swab specimen platform positive preparation reduced Sample sample deliver device SARS-CoV-2 SARS-CoV-2 test sensitivity specimen specimens were used Workflow [DOI] 10.1093/jalm/jfab007 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 Infection in Gargle, Spit, and Sputum Specimens가글, 침, 가래 표본에서 SARS-CoV-2 감염 감지Research Article Published on 2021-08-252022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval acceptability acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alternative testing methods close contact collected Control coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic cycle threshold decrease detection Developing Diagnosis diagnosis of SARS-CoV-2 equipment evaluated gargle gold gold standard Health care health care workers help IMPROVE Infection Nasopharyngeal swab nasopharyngeal swab specimen nose swabs NPs Outpatient overcome Patient reducing respiratory reverse transcription risk of infection sampling strategy SARS-CoV-2 SARS-COV-2 infection sensitivities sensitivity severe acute respiratory syndrome Coronavirus significantly higher specimen specimen collection specimens spit sputum Standard deviation Swab the patient [DOI] 10.1128/Spectrum.00035-21 PMC 바로가기 [Article Type] Research Article
Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samplesResearch Article Published on 2021-08-052022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] approach Asymptomatic conducted COVID-19 demonstrated Detection sensitivity Free gold standard IMPROVE individuals infection prevalence Multiple nasopharyngeal swab specimen nucleic acid extraction Population positive protocol reduce Research RNA RNA extraction RT-qPCR test Saliva SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 surveillance sensitivity specimen Surveillance symptomatic and asymptomatic Testing utility Viral detection Viral RNA [DOI] 10.1371/journal.pone.0255690 PMC 바로가기 [Article Type] Research Article
Effects of Patient Characteristics on Diagnostic Performance of Self-Collected Samples for SARS-CoV-2 TestingResearch Published on 2021-08-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, MERS, [키워드] 2019 novel coronavirus disease acute respiratory syndrome age anterior nasal Atlanta black Characteristics coronavirus coronavirus disease Coronaviruses COVID-19 diagnostic Effect evaluated Georgia healthcare help hospital men nasal swab Nasopharyngeal swab nasopharyngeal swab specimen participant Participants Patient PCR performance physician positive reported respiratory infections Saliva Sample SARS-CoV-2 self-collected sensitivity severe acute respiratory syndrome coronavirus 2 specimen symptom onset tested Testing United States USA viruses zoonoses [DOI] 10.3201/eid2708.210667 PMC 바로가기 [Article Type] Research
Metabolomics in the Diagnosis and Prognosis of COVID-19Genetics Published on 2021-07-232022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] affected Amino acid Analysis approach clinical setting Compound Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 pandemic COVID-19 patient COVID-19 testing detect Diagnosis diagnostic diagnostics dysregulated effort energy metabolism evaluated Factor Genome greater Host independent Infectious disease Kynurenine pathway mass-spectrometry metabolic pathway metabolism metabolite metabolomics nasopharyngeal swab specimen nuclear magnetic resonance outcome pandemic pathway plasma POC point-of-care profile Prognosis prognostic Prognostic marker Protein Research RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA serum severe disease severity significantly specimens Spread Standardization the disease triggered urgency Viral RNA virus Volatile organic compounds with COVID-19 [DOI] 10.3389/fgene.2021.721556 PMC 바로가기 [Article Type] Genetics
Optimal Insertion Depth for Nasal Mid-Turbinate and Nasopharyngeal SwabsArticle Published on 2021-07-142022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age Antigen antigen test calculated clinical evidence clinical validation COVID-19 COVID-19 test Denmark Depth determine Evidence false-negative flexible inferior turbinate insertion lack mid-turbinate sample nasal nasal swab nasopharyngeal nasopharyngeal sample Nasopharyngeal swab nasopharyngeal swab specimen nasopharyngeal swabs pandemic participant provide risk SARS-CoV-2 specimen Swab tested upper respiratory virus virus virus diagnostics [DOI] 10.3390/diagnostics11071257 PMC 바로가기 [Article Type] Article
Genome Sequences of Two Novel Coronavirus (SARS-CoV-2) Isolates from Dhaka, BangladeshGenome Sequences Published on 2021-07-082022-10-29 Journal: Microbiology Resource Announcements [Category] COVID-19, [키워드] acute respiratory syndrome coronavirus coronavirus disease COVID-19 genome sequence isolate nasopharyngeal swab specimen novel Patient SARS-CoV-2 sequence strain [DOI] 10.1128/MRA.00511-21 PMC 바로가기 [Article Type] Genome Sequences
Comparing saliva and nasopharyngeal swab specimens in the detection of COVID-19: A systematic review and meta-analysisReview article Published on 2021-07-012022-10-05 Journal: Journal of Dental Sciences [Category] 치료기술, [키워드] article Boolean operators carried Cochrane Library collected COVID-19 Diagnosis diagnosis of COVID-19 eligibility criteria evaluate Google Scholar Health in vivo LILACS material Meta-analysis Nasopharyngeal swab nasopharyngeal swab specimen no significant difference NPs required Result risk Saliva selected specimen spread of COVID-19 suspected patient systematic literature search The effect size Transmission virus widespread [DOI] 10.1016/j.jds.2021.01.010 [Article Type] Review article
Cervical abscess caused by methicillin-susceptible Staphylococcus aureus in an infant infected with SARS-CoV-2: Diagnostic dilemmaSARS-CoV-2에 감염된 영아의 메티실린 감수성 황색포도상구균에 의한 자궁경부 농양: 진단의 딜레마Case Reports Published on 2021-07-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료기술, [키워드] abscess acute phase acute phase reactant acute phase reactants Administered bacterial co-infection caused ceftriaxone Cervical Cervical abscess cervical lymphadenopathy Chain Reaction children Clindamycin Co-infection COVID-19 COVID-19 disease Culture declined demonstrated diagnosed discharged Drainage elevated emergency department Erythema Fever fluctuation full recovery Hospitalization Immunoglobulin Infant infected with SARS-CoV-2 Inflammatory inflammatory disease inflammatory markers initial initiated Intravenous immunoglobulin IVIG knowledge Laboratory Local Lymphadenopathy magnetic resonance imaging methicillin mind MIS-C multisystem inflammatory syndrome in children (MIS-C) Nasopharyngeal swab nasopharyngeal swab specimen otolaryngologist persistent fever polymerase chain reaction reactants real-time reverse transcriptase-polymerase chain reaction reported reverse transcriptase SARS-CoV-2 SARS-CoV-2 RNA Staphylococcus aureus syndrome tenderness the patient Treatment was performed with COVID-19 [DOI] 10.1016/j.jiac.2021.03.017 PMC 바로가기 [Article Type] Case Reports