Taking on SARS-CoV-2Editorial Published on 2022-06-282023-07-09 Journal: eLife [Category] COVID19(2023년), [키워드] ADCC ADNKA immunology Infectious disease Inflammation Innate immunity Microbiology Natural killer cells SARS-CoV-2 viruses [DOI] 10.7554/eLife.80552 PMC 바로가기 [Article Type] Editorial
Effect of Antiviral Therapy During Pregnancy on Natural Killer Cells in Pregnant Women With Chronic HBV InfectionArticle Published on 2022-05-232023-06-12 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] Antiviral treatment Chronic Hepatitis B Hepatitis B virus Natural killer cells Postpartum [DOI] 10.3389/fimmu.2022.893628 PMC 바로가기
Immunological parameters associated with the severity of COVID-19 pneumonia in kidney transplant recipientsObservational Study Published on 2022-05-012022-10-05 Journal: International urology and nephrology [Category] 임상, [키워드] activated affecting age albumin CD16 CD3 CD4 CD69 CD8 Cell clinical Clinical course control group coronavirus coronavirus disease-2019 Course COVID-19 CRP examined Factor fibrinogen Flow flow cytometry group hemoglobin immunological information kidney transplant recipient Kidney transplantation lymphocyte Lymphocytes natural Natural killer cells NK cell NK cells novel respiratory disease outbreak oxygen parameter patients peak peak D-dimer percentage peripheral pilot study Pneumonia prognostic prospective observational study repeated severe disease severe group severity of COVID-19 subset subtype T cells the patient was used with COVID-19 [DOI] 10.1007/s11255-021-02947-y PMC 바로가기 [Article Type] Observational Study
B Cell Aplasia Is the Most Powerful Predictive Marker for Poor Humoral Response after BNT162b2 mRNA SARS-CoV-2 Vaccination in Recipients of Allogeneic Hematopoietic Stem Cell TransplantationB 세포 무형성은 동종 조혈모세포 이식 환자에서 BNT162b2 mRNA SARS-CoV-2 백신 접종 후 불량한 체액 반응에 대한 가장 강력한 예측 마커입니다Article Published on 2022-05-012022-09-11 Journal: Transplantation and cellular therapy [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] 95% confidence interval absence administration age allo-HSCT Allogeneic allogeneic hematopoietic stem cell transplantation Analysis analyzed anti-SARS-CoV-2 vaccination Antibody Response Antibody responses aplasia B cell B cells B-cell BNT162b2 BNT162b2 mRNA CD4 CD8 characteristic close monitoring Cohort COVID-19 Donor Efficacy entire cohort evaluate evaluated Factor hematopoietic Hematopoietic stem cell highest HSCT humoral Humoral response immune response Immune status Immunosuppressed immunosuppressed patients injection lymphocyte Lymphocyte count lymphopenia median MOST mRNA natural killer cell Natural killer cells Odds ratio of BNT162b2 Patient Poor predict provided recipient recipients reported responders response response rate SARS-CoV-2 SARS-CoV-2 mRNA SARS-CoV-2 vaccination SARS-CoV-2 vaccine Specific STEM stem cell Stem cell transplantation T cell T cells the antibody response transplantation Treatment Univariate analysis Vaccine were assessed [DOI] 10.1016/j.jtct.2022.02.018 PMC 바로가기 [Article Type] Article
Profiling natural killers in COVID-19Editorial Published on 2022-04-012023-07-07 Journal: The Journal of Allergy and Clinical Immunology [Category] COVID19(2023년), [키워드] COVID-19 cytotoxicity Natural killer cells SARS-CoV-2 [DOI] 10.1016/j.jaci.2022.01.002 PMC 바로가기 [Article Type] Editorial
Food nutrients as inherent sources of immunomodulation during COVID-19 pandemicReview article Published on 2022-03-012022-10-05 Journal: LWT [Category] 임상, [키워드] absence acute respiratory syndrome affecting antibody B-cells boosting immunity caused clinical trial clinical trials Community component Compound coronavirus COVID-19 COVID-19 pandemic Defense dendritic cells doses Factor Folic acid food fortified fruits functional globe Host immune component Immune components immune system Immunity Infection inherent initial investigated knowledge Natural killer cells Neutrophils Novel coronavirus Nutrients pathogen Patient reduction in retrospective cohort study SARS-CoV-2 severity of COVID-19 shown Spread stress levels T-cell vaccination Vaccine viral infection [DOI] 10.1016/j.lwt.2022.113154 [Article Type] Review article
SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models우려되는 SARS-CoV-2 변이체는 마우스 모델에서 향상된 고유 병원성 특성 및 확장된 기관 친화성을 나타냅니다.Article Published on 2022-02-152022-09-11 Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] accelerated ACE2 receptor Alpha Alpha variant Antibody neutralization Beta Beta variant cellular cellular immunity curtail cytokine cytokine production Depletion disease Disease progression elicit expand Gamma Gamma variant gastrointestinal tract hACE2 host range human ACE2 immune activation immune responses induce Infection Inflammation innate immune response interferon intrinsic ISG ISG expression K18-hACE2 lung Lungs management mice mouse model murine Natural killer cells neutralization organ pandemic pathogenic pathogenicity reduced replicate responses reveal SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Spread Symptoms systemic infection tissue transgenic Transmissibility Trigger variants variants of concern VoC VOCs wild-type zoonotic transmission [DOI] 10.1016/j.celrep.2022.110387 PMC 바로가기 [Article Type] Article
A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations면역 탈출, 항체 탈출, SARS-CoV-2의 부분 백신 탈출 및 탈출 돌연변이가 있는 이들 변이체에 대한 자세한 개요Review Published on 2022-02-092022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] adopted antibody approach assist AstraZeneca Course cytokine Cytokines D614G dendritic cell dysregulation E484K escape escape mutation help IFN-I Immune escape immune evasion infective innate immune knowledge L452R macrophages Mutation mutations N439K N501Y natural killer cell Natural killer cells neutrophil Neutrophils NLRP3 NLRP3 inflammasome nsp1 Nsp3 NSP6 ORF3 ORF8 P681R pandemic Partial provide PRR PRRs RBD region SARS-CoV-2 the RBD the SARS-CoV-2 vaccination Vaccine vaccine escape variant variants variants of SARS-CoV-2 Viral viral evolution virus ZF2001 [DOI] 10.3389/fimmu.2022.801522 PMC 바로가기 [Article Type] Review
New Discovery of Myeloid-Derived Suppressor Cell’s Tale on Viral Infection and COVID-19Immunology Published on 2022-02-032022-10-31 Journal: Frontiers in Immunology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] addition animal model antigen presenting cells Biomarkers Cancer Cell COVID-19 develop Diseases function Genetic Host immune response immune immune evasion immune regulation Immunopathogenesis include induce Inflammatory MDSC Natural killer cells New Numerous Occurrence pathogen Regulation SARS-COV-2 infection significantly Stress suppress suppressor T-cells Therapeutics tissue damage viral infection virus [DOI] 10.3389/fimmu.2022.842535 PMC 바로가기 [Article Type] Immunology
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations노화된 전혈 전사체는 SARS-CoV-2 관련 혈관 및 면역 변화에 대한 후보 유전자를 나타냅니다Article Published on 2022-02-012022-09-11 Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition adhesion affected age aging alteration anti-apoptotic BAG3 Blood Blood clots blood component blood components candidate candidate gene cascade cathepsin Cathepsins CCL4L2 CD14 CD4 CD8 Cell changes in clinical manifestation coronavirus COVID-19 CTSE CTSW database DEGs differentially expressed gene Differentially expressed genes DUSP4 expressed expression expression levels expression profile FASL FASLG female genders gene expression profile high viral load highest HLA-DRA Hyperinflammatory identify IFN IFN signaling immune immune response increase increase in increased expression individual Inflammation interact Interaction interferon investigated involved LAG3 Monocytes naïve T cells natural killer cell Natural killer cells Older older patient older patients overexpress overexpression PDCD1 Peripheral blood Platelet prediction Protein reveal RGS2 risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected patient SARS-CoV-2-infected patients sequencing data severe acute respiratory syndrome Coronavirus severe COVID-19 Signaling Single-cell RNA-sequencing T cell T cell exhaustion T cells T lymphocytes target targets therapeutic TIGIT TOX Transcriptome translated type I interferon Vascular VCAM1 Viral load Viral protein Viral proteins Whole blood whole blood transcriptome [DOI] 10.1007/s00109-021-02161-4 PMC 바로가기 [Article Type] Article