Neurovascular – Page 3 – Communicable Diseases Research

Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury

7-케토콜레스테롤에 의한 내피 손상에 대한 에르고티오네인의 효과

Article

Published on 2021-03-012022-09-11
Journal: Neuromolecular medicine [Category] 신약개발,

SARS-CoV-2, recurrent ischemic strokes and carotid macrothrombosis: the other face of the cytokine storm (a case report)

Case Report

Published on 2021-01-132022-10-28
Journal: The Pan African Medical Journal [Category] COVID-19,

Molecular Mechanisms of Proteins — Targets for SARS-CoV-2 (Review)

단백질의 분자 메커니즘 — SARS-CoV-2의 표적(검토)

Review

Published on 2020-12-282022-09-10
Journal: Modern Technologies in Medicine [Category] MERS, SARS, 치료기술, 치료제,

[키워드] accumulating ACE2 Activation Affect affected angiotensin Angiotensin 1-7 Angiotensin II Angiotensin-converting enzyme angiotensin-converting enzyme 2 astrogliosis basal ganglia blood-brain barrier Brain brain damage brain damage in COVID-19 brain tissue breakdown caused CD147 Central nervous system Cerebellum change CNS coronavirus Coronavirus infection COVID-19 Cytokines damage death develop disease Diseases driven by Endothelial cell endothelial cells enzyme Evidence exposure to expressed Extracellular matrix functional ganglia help hypothalamus inducer Infection information interactions leads leukocyte leukocytes Local massive matrix metalloproteinases mechanisms membrane permeability metabolism microglia midbrain molecular mechanism molecular mechanisms moment nasal epithelium Neuroinflammation neurons Neurovascular New coronavirus new coronavirus SARS-CoV-2 pathogen Pathogenesis pathogenesis of COVID-19 Piriform cortex Proinflammatory cytokine proinflammatory cytokines pulmonary symptoms Research review SARS-CoV-2 Serine serine protease serine protease TMPRSS2 substantia substantia nigra target target proteins the disease TMPRSS2 Treatment Vascular Via virus virus spread
[DOI] 10.17691/stm2020.12.6.11 PMC 바로가기 [Article Type] Review

Cerebral Venous Thrombosis in Patients with COVID-19 Infection: a Case Series and Systematic Review

COVID-19 감염 환자의 대뇌 정맥 혈전증: 사례 시리즈 및 체계적인 검토

Case Reports

Published on 2020-12-012022-09-11
Journal: Journal of stroke and cerebrovascular diseases : t [Category] MERS, 바이오마커, 진단,

[키워드] antibodies anticoagulation antiphospholipid antibodies Case series case sery cerebral Cerebral venous thrombosis conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients COVID-19 symptom COVID-19 symptoms CRP level CRP levels D-dimer Diagnosis dimer disease early treatment had no high mortality rate in some initiated ischemic strokes Local majority median median age medical condition Mortality Most patient Most patients Neurovascular overall mortality pathophysiology Patient Physicians proportion raised reported review Sery sigmoid sinus Singapore stroke suspicion systematic review thromboembolic thrombosis Two patient two patients venous venous sinus Venous Thromboembolism Venous thrombosis with COVID-19
[DOI] 10.1016/j.jstrokecerebrovasdis.2020.105379 PMC 바로가기 [Article Type] Case Reports

COVID-19 Impact on Neurosurgical Practice: Lockdown Attitude and Experience of a European Academic Center

Observational Study

Published on 2020-12-012022-10-05
Journal: World neurosurgery [Category] 임상,

Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications

Article

Published on 2020-09-082022-10-30
Journal: Molecular neurobiology [Category] COVID-19, MERS, SARS,

[키워드] activated addition Affect affecting Aminoacridine anti-inflammatory agents Anti-inflammatory drugs antimalarial Antimalarials Aortic body arachidonic acid blood vessels Brain endothelial cells carotid body Cell culture Central nervous system Chloroquine clinical trial CNS combating Complication coronavirus coronavirus disease Coronavirus replication COVID COVID-19 COX cPLA₂ cross cytokine Cytokine storm cytosolic Cytosolic phospholipase A₂ Dementia disorder DMT1 drug Effect Eicosanoids ENhance expression free radical Free radical damage free radical formation generate Glossopharyngeal nerve hippocampus Hydroxychloroquine Hypoxemia impair induce Inflammation Inflammatory response inhibit inhibiting inhibition inhibitor iron accumulation Iron transport isoform isoforms lung lysosomal enzymes lysosome Lysosomes mice Microcirculation microglia Microvessels Neuroinflammation Neurovascular Nucleus of the tractus solitarius organ oxidative damage oxidative stress PLA2G2D pro-inflammatory produced quinacrine reducing Respiratory centre resulting SARS SARS-CoV SARS-CoV-2 SARS-CoV-2 virus Secretory phospholipase A₂ Seizures severe cases shown silent sPLA₂ IID statins stroke the SARS-CoV-2 virus tissue TNF-α Treatment unique vagus nerve Vascular vascular dementia viral replication
[DOI] 10.1007/s12035-020-02093-z PMC 바로가기 [Article Type] Article

Opioid and neuroHIV Comorbidity – Current and Future Perspectives

아편유사제 및 neuroHIV 동반 질환 – 현재 및 미래 전망

Review

Published on 2020-09-022022-09-10
Journal: Journal of neuroimmune pharmacology : the official [Category] MERS, 변종, 유전자 메커니즘,

[키워드] μ-Opioid receptor (OPRM1) Antiretroviral therapy Astrocyte blood-brain barrier Brain breakdown Buprenorphine C-C motif chemokine receptor 5 (CCR5) cellular Central nervous system chemokine Clinical studies clinical study CNS Comorbidity Compound consequence COVID-19 Critical current Cytochrome P450 3A4 (CYP 3A4) disease disorder drugs Endogenous opioid system of peptides and receptors experimental models expression focus functional Functional selectivity/biased agonism Future gene product genetic variants hand HIV HIV-1 HIV-associated neurocognitive disorders Host Human immunodeficiency virus immunodeficiency virus include increase Interaction key consideration key considerations Maladaptive neuroplasticity mechanism Methadone methodology microglia molecular National neuroHIV Neurovascular not seen Oligodendroglia opiate opioid opioids P-glycoprotein Pathogenesis pathophysiologic pathophysiology penetration Pro-brain-derived neurotrophic factor (pro-BDNF) Prognosis progression Protein question recent receptor severity Synaptodendritic degeneration tight junction unique variants with HIV
[DOI] 10.1007/s11481-020-09941-8 PMC 바로가기 [Article Type] Review

Central nervous system complications associated with SARS-CoV-2 infection: integrative concepts of pathophysiology and case reports

Review

Published on 2020-08-062022-10-30
Journal: Journal of Neuroinflammation [Category] COVID-19, MERS,

[키워드] ACE2 activate acute respiratory syndrome ARDS Autoimmunity beta-coronavirus blood-brain barrier Brain C-reactive protein Case report caused Central nervous system chemokines CNS Complication contributing to coronavirus Coronavirus disease 2019 CoV COVID-19 CoVs Critical CRP Cytokines Direct disorders disrupt dysregulation elevated Encephalitis Encephalopathy endothelial cells endothelial function Endotheliitis Fever highlight hyper-inflammation Hyperferritinemia hypoxemic illnesses impair include induce Inflammatory responses innate immune Innate immunity lymphocytopenia MERS-CoV microglia Middle East multi-organ system dysfunction nervous system Neurological complication Neurovascular Novel coronavirus pandemic Pathogenesis pathophysiology pro-inflammatory mediators Protein provide RAS renal respiratory Respiratory failure respiratory symptom SARS-CoV SARS-CoV-2 SARS-COV-2 infection secondary hemophagocytic lymphohistiocytosis signaling pathways stroke syndrome systemic hyper-inflammation Thrombotic events upregulation viral infection with COVID-19
[DOI] 10.1186/s12974-020-01896-0 PMC 바로가기 [Article Type] Review

Impact of the COVID-19 pandemic on patients suffering from musculoskeletal tumours

Original Paper

Published on 2020-05-262022-10-29
Journal: International Orthopaedics [Category] COVID-19, MERS, SARS,