Angiostrongylus cantonensis in a Red Ruffed Lemur at a Zoo, Louisiana, USAArticle Published on 2022-05-012023-06-14 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] aberrant host Angiostrongylus Angiostrongylus cantonensis lemur Louisiana nematode North America parasites United States zoonoses [DOI] 10.3201/eid2805.212287 PMC 바로가기
Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA)Research article Published on 2022-04-212022-10-05 Journal: EClinicalMedicine [Category] 바이오마커, 임상, [키워드] 28-day mortality 95% CI anti-SARS-CoV-2 antibody antibody Antibody Response assessment assigned authority benefit clearance combination therapy Coronavirus disease 2019 Coronavirus disease-19 COVACTA COVID-19 Department development died discharged double-blind Effect Efficacy and safety Europe finding funding Future Hoffmann-La Roche hospital hospital discharge hospitalised Host immune response Human impair IMPROVE Infection intensive care interleukin-6 intravenous tocilizumab investigated Mortality Nasopharyngeal swab neutralising North America occurred office other treatments Patient patient selection patients with COVID-19 Placebo placebo-controlled trial polymerase chain positive test result Potential biomarker randomised randomised controlled trial Randomly respiratory response SARS-CoV-2 SARS-CoV-2 viral load Secretary serum serum samples severe acute respiratory syndrome coronavirus-2 tested Tocilizumab Treatment viral clearance Viral load with COVID-19 [DOI] 10.1016/j.eclinm.2022.101409 [Article Type] Research article
Early Emergence Phase of SARS-CoV-2 Delta Variant in Florida, US미국 플로리다에서 SARS-CoV-2 델타 변종 초기 출현 단계Article Published on 2022-04-062022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] addition Asia B.1.617.2 benefit causative agent clade contagious COVID-19 Delta delta variant demonstrated dominant lineage early emergence effort emergence Epidemic Epidemiology Europe FIVE Florida genomes genomic Genomic analysis independent India Local MONITOR North America pandemic phase Phylogenetic analysis prevalent Public health responses SARS-CoV-2 Spread subsequent Substitution Support Surveillance Transmission Transmission dynamics understanding variant variants VoC [DOI] 10.3390/v14040766 PMC 바로가기 [Article Type] Article
Early-stage Alzheimer disease: getting trial-ready Reviews Published on 2022-04-042022-10-05 Journal: Nature reviews. Neurology [Category] 바이오마커, 변종, 임상, [키워드] accelerate accelerated Alzheimer disease approval Asia Asymptomatic Biomarker Brain clinical trial Cohort collaboration determine disease effective Efficiency effort eligibility engage Europe example FDA individual initiated medical need Modification North America participant Participants performed progression randomize recruit recruitment required risk Stage study participant symptomatic the disease therapeutic therapeutic intervention therapy Trial trials [DOI] 10.1038/s41582-022-00645-6 [Article Type] Reviews
Geographical prevalence of SARS-CoV-2 variants, August 2020 to July 20212020년 8월부터 2021년 7월까지 SARS-CoV-2 변종의 지리적 유행Article Published on 2022-03-182022-09-11 Journal: Scientific Reports [Category] SARS, 변종, [키워드] accompanied Alpha analyzed Asia Beta Brazil country Coverage COVID-19 case COVID-19 cases database death deaths Delta Delta VOC Efficacy Europe Gamma genomic data geographical regions GISAID growth immunization IMPROVE Lineage North America Oceania Perspective predicted predominant Prevalence proportion proportions SARS-CoV-2 variant SARS-CoV-2 variants South America suggested surveillance data vaccination Vaccination Status Vaccine vaccine efficacy variant variants VoC [DOI] 10.1038/s41598-022-08684-1 PMC 바로가기 [Article Type] Article
Trust in scientific information mediates associations between conservatism and coronavirus responses in the U.S., but few other nationsArticle Published on 2022-03-082022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] association Canada Compliance coronavirus Coronavirus infection country evaluate Evidence Human behaviour indirect effect Indonesia Infection information less lockdown restrictions North America pandemic Psychology recruited replicate Research response strongly related Support Trust yielding [DOI] 10.1038/s41598-022-07508-6 PMC 바로가기 [Article Type] Article
Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial무작위 대조 시험에서 토실리주맙으로 치료된 2019 코로나바이러스 질환 환자의 예후 및 예측 바이오마커Clinical Trial Published on 2022-03-012022-09-11 Journal: Critical Care Medicine [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] (interleukin-6 additional sensitivity analyses Analysis antibody assigned binomial Biomarker Biomarkers C-reactive protein candidate Clinical outcome clinical outcomes clinical status Controlled coronavirus disease Coronavirus disease 2019 COVACTA D-dimer death dimer double-blind Effect Europe evaluated Exploratory analysis ferritin ferritin level hospital discharge Hospitalized Interaction interleukin interleukin-6 Lactate lactate dehydrogenase Lymphocytes measurement mechanical ventilation modeling Monocytes Mortality multicenter Multiple Neutrophils North America observational study Ordinal Scale outcome Patient patients hospitalized phase 3 trial Placebo placebo-controlled Platelets Pneumonia Predictive Predictive value prognostic randomization Randomized Randomly receiving receptor retrospective seven-category ordinal scale severe coronavirus disease standard care Tocilizumab treatment with tocilizumab Trial were measured [DOI] 10.1097/CCM.0000000000005229 PMC 바로가기 [Article Type] Clinical Trial
Safety and humoral response rate of inactivated and mRNA vaccines against SARS-CoV-2 in patients with Multiple Sclerosis다발성 경화증 환자에서 SARS-CoV-2에 대한 비활성화 및 mRNA 백신의 안전성 및 체액 반응률Observational Study Published on 2022-03-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adenoviral vector vaccine Adverse age Analysis anti-SARS-CoV-2 vaccines Antibody titre antibody titres booster collected Complete COVID-19 Effectiveness Europe event Evidence first vaccination help humoral Humoral response inactivated Inactivated vaccine Inactivated virus information local pain mRNA mRNA vaccine Multiple multiple sclerosis no increase North America outcome Oxford-AstraZeneca Patient patient cohort patients performed populations positive predictor Protein receiving Safe Safety SARS-CoV-2 sclerosis selected significantly lower therapy vaccination Vaccine virus was determined were recorded women [DOI] 10.1016/j.msard.2022.103690 PMC 바로가기 [Article Type] Observational Study
Pediatric Malaria: Global and North American Perspectivesarticle Published on 2022-02-282024-09-01 Journal: Pediatric Clinics of North America [Category] 말라리아, [키워드] artemether-lumefantrine artesunate children malaria North America [Article Type] article
The global case fatality rate of coronavirus disease 2019 by continents and national income: A meta‐analysisResearch Article Published on 2022-02-252022-11-01 Journal: Journal of medical virology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Asia Case fatality rate CFR change Continents coronavirus disease country COVID‐19 COVID‐19 declining effort estimate estimates Europe Fatality rate Final fixed geographical region gradually increased highest more accurate representation Mortality National North America peaked performed proportion meta‐analysis random reached remained shown Socioeconomic Factors South America [DOI] 10.1002/jmv.27610 PMC 바로가기 [Article Type] Research Article