nucleotide substitution – Page 3 – Communicable Diseases Research

Computational analysis of SARS-CoV-2, SARS-CoV, and MERS-CoV genome using MEGA

Original Article

Published on 2020-09-242022-11-01
Journal: Genomics & Informatics [Category] COVID-19,

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

530

Published on 2020-09-222022-10-29
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,

[키워드] ACE2 receptor acute respiratory syndrome adaptive affecting analyses binding bioinformatics circulating circulating variant comparable Consensus coronavirus COVID-19 COVID-19 pandemic D614G mutation effective event Evidence Evolution explain Genes genetics genomes homogeneous immunogenic in viral lineages magnitude median mutate Mutation mutations Neutral neutralizing antibody nucleotide substitution Phylogenetic polymorphism Population Protein question raise reference sequence Safe SARS-CoV-2 SARS-CoV-2 genomes SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 vaccine sequence Seven Significance single vaccine spike Spread the Spike transmitted urgency Vaccine vaccine candidate vaccine candidates variant virus while Wuhan-Hu-1
[DOI] 10.1073/pnas.2008281117 PMC 바로가기 [Article Type] 530

Molecular Tracing of SARS-CoV-2 in Italy in the First Three Months of the Epidemic

Article

Published on 2020-07-242022-10-28
Journal: Viruses [Category] COVID-19, SARS,

Identification of the nucleotide substitutions in 62 SARS-CoV-2 sequences from Turkey

Article

Published on 2020-06-212022-10-29
Journal: Turkish Journal of Biology [Category] COVID-19,

Investigating the genomic landscape of novel coronavirus (2019-nCoV) to identify non-synonymous mutations for use in diagnosis and drug design

Article

Published on 2020-05-152022-11-01
Journal: Journal of Clinical Virology [Category] COVID-19, MERS, SARS,

[키워드] 2019-nCoV Amino acid amino acid change Analysis antiviral therapies Bat-hCoV Care combinatorial treatment coronavirus death Diagnosis drug drug design Efficacy effort explain extreme feature Genome genomic group HCoV Health identify indicated infecting inhibitory isolate lack Mutation Non-synonymous Non-synonymous mutation nonsynonymous substitution novel Novel coronavirus nucleotide nucleotide substitution Occurrence other coronaviruses Pangolin-hCoV Pathogenesis pathogenicity Patient Phylogenetic analysis Phylogeny Protein resulting SARS SARS-CoV2 similarity Spike protein Substitution synonymous Synonymous and non-synonymous substitutions therapy Treatment Vaccine viral genome Viral protein virus
[DOI] 10.1016/j.jcv.2020.104441 PMC 바로가기 [Article Type] Article

Estimated resistance of the malaria mosquito Anopheles messeae s.l. to the insecticide malathion

article

Published on 2019-06-302024-09-01
Journal: Journal of Vector Ecology [Category] 말라리아,

[키워드] ace-1 gene Anopheles messeae s.l Insecticide resistance LC50 Malathion nucleotide substitution
[Article Type] article

Euclidean Distance Analysis Enables Nucleotide Skew Analysis in Viral Genomes

Research Article

Published on 2018-10-302022-10-31
Journal: Computational and Mathematical Methods in Medicine [Category] Coronavirus,

Allelic Variation in CXCL16 Determines CD3 + T Lymphocyte Susceptibility to Equine Arteritis Virus Infection and Establishment of Long-Term Carrier State in the Stallion

CXCL16의 대립형질 변이는 말 동맥염 바이러스 감염에 대한 CD3 + T 림프구 감수성과 종마의 장기 보균자 상태 확립을 결정합니다

Research Article

Published on 2016-12-082022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] acute infection allele allelic variant Amino acid amino acid change arteritis association carrier carrier state carriers causative agent CD3 cellular receptor cellular receptors chromosome 11 correlated correlated strongly CXCL16 demonstrated determine disease dominant equine ExoN exon 1 exposure to Genetic Genome Genome wide association study GWAS higher risk Ile Illumina implicated in vitro In vitro infection infect Infection inheritance Laboratory lack less life lymphocyte Lymphocytes maintenance male MOST Mutation natural infection Non-synonymous nucleotide nucleotide substitution nucleotide substitutions orthologue outcome persistence phenotype Phenotypes phenotypic phenotypic trait Previous studies previous study Probability proportion Protein protein isoform Proteins receptor reported reproductive required respiratory responsible risk scavenger receptor Semen shown significantly higher significantly lower Stallion susceptibility susceptible T lymphocyte T lymphocytes Two alleles Viral viral persistence virus virus carriers were used
[DOI] 10.1371/journal.pgen.1006467 PMC 바로가기 [Article Type] Research Article

Small Interfering RNA Effectively Inhibits the Expression of SARS Coronavirus Membrane Gene at Two Novel Targeting Sites

Article

Published on 2010-10-182022-10-30
Journal: Molecules [Category] Coronavirus,

Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003

Research Article

Published on 2004-09-062022-10-28
Journal: BMC Infectious Diseases [Category] Coronavirus,

[키워드] 2003 3CLpro adjusted Analysis antigenic antigenic protein appear arising calculated Cell culture China Co-infection Complete Contact Culture cultured isolate Deletion different estimate FIVE found functional Gene Genes Genetic Genome greater group growth hotel human population human populations human tissue human-to-human transmission in vitro in vivo isolate isolates molecular Mutation mutation rate Non-synonymous mutation North nucleotide substitution ORF ORFs passage pathogen Patient per day polymerase Proteins related respiratory Result RNA virus SARS Coronavirus SARS-CoV selection pressure sequence sequenced severe Singapore Taiwan the epidemic the SARS epidemic tissue sample Transmission transmission patterns undergo Vero Cell viral genome was used whole genome sequence
[DOI] 10.1186/1471-2334-4-32 PMC 바로가기 [Article Type] Research Article