Positive selection as a key player for SARS-CoV-2 pathogenicity: Insights into ORF1ab, S and E genes
SARS-CoV-2 병원성의 핵심 플레이어로 양성 선택: ORF1ab, S 및 E 유전자에 대한 통찰력
Article
[키워드] adaptive
analysis
approaches
C-terminal
cause
codon
Codons
composed
COVID-19 disease
disease
domain
drug
drug targeting
E gene
E protein
Each
encoded proteins
Evidence
evidence of
Evolution
functional
Genes
Host
Host immune response
Human
hydrophilic
in viral
inhibiting
insight
involved
likelihood
maximum
Maximum likelihood
N-terminal domain
non-structural protein
non-structural proteins
nonstructural protein
nsp1
Nsp3
ORF1
ORF1a
ORF1ab
ORF1b
pandemic
pathogenicity
performed
Positive selection
Protein
protein domains
protein-coding gene
residues
SARS-CoV-2
SARS-CoV-2 epidemic
SARS-CoV-2 genome
SARS-CoV-2 genomes
SARS-CoV-2.
Ser
stability
structural protein
structural proteins
Substitution
substitutions
survival
target
targets
the S protein
the SARS-CoV-2
Transcription
translation
transmembrane
transmembrane domain
Transmissibility
Vaccine
viral replication
virulent
virus
vital role
vital roles
Wuhan
Wuhan, China
β-coronavirus
β-coronavirus
[DOI] 10.1016/j.virusres.2021.198472 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.virusres.2021.198472 PMC 바로가기 [Article Type] Article