oseltamivir – Page 3 – Communicable Diseases Research

Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip

Research Article

Published on 2021-09-152022-10-30
Journal: Microbiology Spectrum [Category] COVID-19, SARS,

Baloxavir-oseltamivir combination therapy inhibits the emergence of resistant substitutions in influenza A virus PA gene in a mouse model

Article

Published on 2021-09-012023-06-23
Journal: Antiviral Research [Category] 신종인플루엔자,

[키워드] antiviral susceptibility baloxavir combination therapy Influenza oseltamivir PA-I38X.
[DOI] 10.1016/j.antiviral.2021.105126

Clinical and virological outcomes with baloxavir compared with oseltamivir in pediatric patients aged 6 to < 12 years with influenza: an open-label, randomized, active-controlled trial protocol

Study Protocol

Published on 2021-08-092022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19,

[키워드] administration all subject Antiviral treatment approved baloxavir baloxavir marboxil Child clinical Clinical trial protocol Complication conducted cough criteria demonstrated dose Efficacy and safety Endpoint Evidence Granule include Infection Influenza influenza infection influenza treatment Influenza virus inhibit intention-to-treat Japan Japanese median time Mild multicenter nasal Open-label oseltamivir outcome pediatric Pediatric patient primary analysis population Randomized Randomly receive registry safety population single dose study drug subject sustained Symptom Transmission Trial trial protocol virological outcome
[DOI] 10.1186/s12879-021-06494-w PMC 바로가기 [Article Type] Study Protocol

Virological and clinical outcomes in outpatients treated with baloxavir or oseltamivir: A Japanese multicenter study in the 2019-2020 influenza season

Observational Study

Published on 2021-08-012023-06-23
Journal: Antiviral Research [Category] 신종인플루엔자,

[키워드] baloxavir clinical setting Efficacy Influenza oseltamivir variant
[DOI] 10.1016/j.antiviral.2021.105092 [Article Type] Observational Study

Arbidol is associated with increased in-hospital mortality among 109 patients with severe COVID-19: A multicenter, retrospective study

Research Theme 1: COVID-19 Pandemic

Published on 2021-07-172022-10-31
Journal: Journal of Global Health [Category] COVID-19,

[키워드] 95% confidence interval addition adjusted age Analysis analyzed antiviral agent antiviral therapy antiviral treatments Arbidol association co-morbidities Combination complications COVID-19 patients demographics determine died discharged Effect Effectiveness enrolled hospital Hospitalization IFN-α in-hospital mortality indicated interferon-alpha Intervention Laboratory Logistic regression monotherapy multicenter Odds ratio oseltamivir other treatment Patient Prognosis Result Retrospective study ribavirin severe COVID-19 patient severe COVID-19 patients survival Treatment variables Wuhan, China
[DOI] 10.7189/jogh.11.05017 PMC 바로가기 [Article Type] Research Theme 1: COVID-19 Pandemic

Effects of Immune System-Related Medications on COVID-19 Outcome in a Cohort of Iranian Patients: Preliminary Report of a Data Mining Study

면역 체계 관련 약물이 이란 환자 집단에서 COVID-19 결과에 미치는 영향: 데이터 마이닝 연구의 예비 보고서

Research Article

Published on 2021-07-022022-09-10
Journal: Journal of Immunology Research [Category] SARS, 치료제,

[키워드] 95% CI 95% confidence interval 95%CI age antivirals association can be used clinics Cohort condition coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 Critical death Effect Evidence failure hospital Hydroxychloroquine hyperactivity ICU admission immune immune system in some incidence rate Interaction interactions Iran latent variables Logistic regression LOS Medical Sciences medication Mortality Odds ratio oseltamivir outcome Patient Poisson regression Prednisolone rate ratio reduce mortality reduction report Result risk factor Tehran Treatment university variable Viral viral infections was increased was performed was used
[DOI] 10.1155/2021/9934134 PMC 바로가기 [Article Type] Research Article

Effect of COVID-19 medications on corrected QT interval and induction of torsade de pointes: Results of a multicenter national survey

교정 QT 간격 및 Torsade de Pointes 유도에 대한 COVID-19 약물의 영향: 다기관 국가 조사 결과

Multicenter Study

Published on 2021-07-012022-09-11
Journal: International journal of clinical practice [Category] SARS, 치료제,

[키워드] addressed administration Amiodarone arrhythmia Atazanavir Azithromycin Chloroquine Cohort Combination combination therapy coronavirus coronavirus disease COVID-19 COVID-19 patient Critical death demonstrated during treatment Effect Favipiravir female gender furosemide heart failure hepatic dysfunction hospital hospitalised Hydroxychloroquine hypokalaemia incidence inclusion criteria Iran life-threatening Lopinavir Lopinavir-ritonavir Lopinavir/ritonavir medication medications multicenter National occurred oseltamivir Patient patients predicted Primary outcome Prospective Study QT interval QT prolongation QTc QTC prolongation Remdesivir renal reported Repurposed drug Repurposed drugs Result risk Ritonavir secondary outcome Secondary outcomes Side effect therapy Torsade de Pointes treated Treatment
[DOI] 10.1111/ijcp.14182 PMC 바로가기 [Article Type] Multicenter Study

COVID-19 in Turkey: A tertiary center experience

터키의 COVID-19: 3차 센터 경험

Article

Published on 2021-07-012022-09-11
Journal: Pediatrics international : official journal of the [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition Adult patients Azithromycin caused children clinical feature Combination Comorbidities Contact contact with coronavirus disease Coronavirus-2 country COVID-19 COVID-19 infection Critical D-dimer value diagnosed with COVID-19 disease Epidemic epidemiological Health health problem healthy Hydroxychloroquine Infection Invasive mechanical ventilation Laboratory lymphocyte Lymphocytes male median age Medical conditions Mild mild infection moderate non-invasive mechanical ventilation oseltamivir Patient radiological finding required SARS-CoV-2 SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe or critical illness the SARS-CoV-2 virus was used
[DOI] 10.1111/ped.14549 PMC 바로가기 [Article Type] Article

Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2

Article

Published on 2021-06-012022-10-04
Journal: Journal of biomolecular structure & dynamics [Category] SARS, 신약개발,

Available medications used as potential therapeutics for COVID-19: What are the known safety profiles in pregnancy

COVID-19의 잠재적 치료제로 사용 가능한 약물: 임신 중 알려진 안전성 프로파일은 무엇입니까?

Research Article

Published on 2021-05-192022-09-10
Journal: PLoS ONE [Category] SARS, 신약개발, 치료제,

[키워드] 95%CI Adjusting age angiotensin ARB Azithromycin Birth weight blocker caution Chloroquine clinical trial clinical trials condition confounder confounders congenital malformation COVID-19 Dexamethasone during pregnancy eligible excluded exposure to gestational age gestational period heparin heparins HIV Hydroxychloroquine increased risk indication indications interferon interferons LBW Low birth weight medication medications oseltamivir outcomes Potential treatment potential treatments pregnancies Pregnancy pregnant women Prematurity quantified Result risk safety profile Taking treat treatments for COVID-19 trials unique with COVID-19 women
[DOI] 10.1371/journal.pone.0251746 PMC 바로가기 [Article Type] Research Article