Cycle threshold responses in SARS-COV2 PCR tests depend on the method by which the samples were obtained and require strict global standardizationSARS-COV2 PCR 테스트의 주기 임계값 응답은 샘플을 얻은 방법에 따라 다르며 엄격한 글로벌 표준화가 필요합니다.Article Published on 2022-08-012022-09-11 Journal: Infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis CDC Ct values cycle cycle threshold detect determine emergency room Epidemic false negatives hospitals include PCR PCR test penetration platform reduce response risk SARS-CoV2 Schools Standardization Swab threshold Viral load virus [DOI] 10.1007/s15010-022-01772-4 PMC 바로가기 [Article Type] Article
Safety and immunogenicity of the FINLAY-FR-1A vaccine in COVID-19 convalescent participants: an open-label phase 2a and double-blind, randomised, placebo-controlled, phase 2b, seamless, clinical trialCOVID-19 회복기 참가자에 대한 FINLAY-FR-1A 백신의 안전성 및 면역원성: 공개 라벨 2a상 및 이중 맹검, 무작위 배정, 위약 대조, 2b상, 심리스, 임상 시험Clinical Trial Published on 2022-08-012022-09-11 Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 95% CI adverse event All participants Alpha anti-RBD antibody assigned Asymptomatic Beta clinical clinical trial clinical trials Complete control group control groups convalescent convalescent individual convalescent individuals COVID-19 criteria Cuba defined delta variant Delta variants dimeric double-blind education elicited ELISA Endpoint enrolled Environment evaluate evaluated experimental group first stage geometric mean geometric mean titre geometric mean titres greater hematology ICTRP IgG antibodies immune response immunogenicity immunology increase in injected injection injection site Intervention intervention group Mild minor Moderate COVID-19 natural immunity Negative PCR neutralisation test neutralising antibody Occurrence Open-label Pain participant Participants PCR test per-protocol population Phase 1 Phase 2 Placebo placebo group placebo-controlled prevaccination Primary outcome Primary outcomes Public randomised Randomly Receptor binding domain recruited Registered registry reported Safety safety analysis safety population safety profile SARS-CoV-2 Science seamless secondary Secondary endpoints Serious Adverse Event Serious Adverse Events seroconversion rate sexual single dose stages study population technology the placebo group titre Trial two groups vaccination Vaccine vaccine immunogenicity Virus neutralisation Volunteer was done WHO-ICTRP [DOI] 10.1016/S2213-2600(22)00100-X PMC 바로가기 [Article Type] Clinical Trial
COVID-19 Testing Strategies for K-12 Schools in California: A Cost-Effectiveness Analysis캘리포니아의 K-12 학교를 위한 COVID-19 테스트 전략: 비용 효율성 분석Article Published on 2022-07-302022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] Analysis Antigen Asymptomatic benefit community transmission conducted Cost effectiveness Cost-effectiveness analysis COVID-19 COVID-19 pandemic declines Follow-up Frequency Guidance Health help individuals Infection K-12 moderate omicron PCR PCR test PCR tests positive Prevalence Public Quality-Adjusted Life Years reduce resource SARS-CoV-2 antigen School Schools Screening screening strategy Secondary infection secondary infections Sensitivity analyses sensitivity analysis Strategy Testing Transmission twice weekly variant Weekly widespread [DOI] 10.3390/ijerph19159371 PMC 바로가기 [Article Type] Article
Temporal trends and differences of SARS-CoV-2-specific antibody responses in symptomatic and asymptomatic subjects: a longitudinal study from Umbria in Italy증상이 있는 대상과 무증상 대상에서 SARS-CoV-2 특이 항체 반응의 시간적 경향과 차이점: 이탈리아 Umbria의 종단 연구Article Published on 2022-07-182022-09-11 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] anti-S anti-S antibody antibody Antibody Response Antibody responses Antibody titre antibody titres Asymptomatic Clinical severity clinically Cohort correlation COVID-19 Decline Diagnosis discharged Dynamics eligible first visit Follow-up follow-up study group hospital Immunity immunology Infectious diseases Italy longitudinal overtime participant Participants PCR test persistence positive Protein recruited reduced Reinfection remained SARS-CoV-2 SARS-COV-2 infection serological Serological testing significant difference significantly higher Signs and symptoms spike Spike proteins subject subjects Symptom symptomatic symptomatic and asymptomatic Temporal the median three group three groups threshold titre titres Treatment two groups U/mL Variation Virology while without symptom [DOI] 10.1136/bmjopen-2021-056370 PMC 바로가기 [Article Type] Article
COVID-19 increases the risk for the onset of atrial fibrillation in hospitalized patientsCOVID-19는 입원 환자의 심방세동 발병 위험을 높입니다Article Published on 2022-07-142022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, 치료법, [키워드] 95% CI Adequate Affect Analysis association Atrial fibrillation atrial flutter Cohort Comorbidities Comorbidity COVID-19 COVID-19 negative COVID-19 positive patient COVID-19 positive patients demographics demonstrated described detect disease electronic medical record electronic medical records eligible for inclusion hospital Hospitalized hospitalized patient hospitalized patients increase increase in increased risk Infection mass morbidity morbidity and mortality multivariable logistic regression myocardial involvement Patient patients patients with COVID-19 PCR test reduce Retrospective study risk risk factor SARS-CoV-2 screened Symptoms Treatment treatment regimen treatment regimens while [DOI] 10.1038/s41598-022-16113-6 PMC 바로가기 [Article Type] Article
Anti-nucleocapsid antibody levels and pulmonary comorbid conditions are linked to post-COVID-19 syndrome항뉴클레오캡시드 항체 수준 및 폐 동반질환 상태는 코로나19 이후 증후군과 관련이 있습니다Article Published on 2022-07-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] age allergy antibody Antigen Asthma Asymptomatic Biohub Biomarker Biomarkers blood draw blood draws center Cohort comorbid condition COVID-19 disease COVID-19 disease severity COVID-19 infections Critical CTSA Diagnosis disease disease severity Ethnic groups Ethnicity Factor foundation IgG IgG response immunoglobulins in-person visit Infectious disease initial initiative Lung disease median time nasal swab NIH not affect nucleocapsid IgG participant Patient PCR test PCR-positive positive RT-PCR ranged recruited Remdesivir reported reverse transcription risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid Sean Sex Stanford Stanford University Study participants sustained Symptom symptom resolution Symptoms syndrome with COVID-19 [DOI] 10.1172/jci.insight.156713 PMC 바로가기 [Article Type] Article
The importance of disease prevalence in clinical decision making: a real practice study on COVID-19 antigen test in CuracaoShort communication Published on 2022-07-012022-10-05 Journal: The Brazilian journal of infectious diseases : an [Category] 진단, [키워드] 95% CI Ag-RDT Antigen clinical decision costly COVD-19 COVID-19 COVID-19 pandemic Department diagnostic diagnostic test Disease prevalence Emergency False positive hospital investigated Molecular tests Negative predictive value Patient patients PCR test performance positive Positive predictive value Positive test Rapid rapid antigen test sensitivity specificity Test was performed [DOI] 10.1016/j.bjid.2022.102389 [Article Type] Short communication
The latent period of coronavirus disease 2019 with SARS-CoV-2 B.1.617.2 Delta variant of concern in the postvaccination era2019년 SARS-CoV-2 B.1.617.2 예방 접종 후 시대 우려 델타 변종 코로나바이러스 질병 잠복기Article Published on 2022-07-012022-09-11 Journal: Immunity, Inflammation and Disease [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 B.1.617.2 Clinical data collected comparable coronavirus coronavirus disease COVID-19 Date delta variant Delta VOC distribution Epidemic Epidemiology female patient Female patients first positive Infection interquartile range latent period male median median age not significantly different Patient patients PCR test postvaccination Prevent Prevention and control quarantine retrospective SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 the SARS-CoV-2 Transmission Vaccine variant variant of concern VoC [DOI] 10.1002/iid3.664 PMC 바로가기 [Article Type] Article
Comparison of extraction-based and elution-based polymerase chain reaction testing, and automated and rapid antigen testing for the diagnosis of severe acute respiratory syndrome coronavirus 2중증급성호흡기증후군 코로나바이러스 2 진단을 위한 추출기반 및 용출기반 중합효소연쇄반응검사와 자동화 및 신속항원검사의 비교Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification amplified Antigen antigen detection applied assays automated Chain Reaction clinical sample clinical samples Concentration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis diagnostic diagnostic test Dilution dilutions disease Elecsy Elecsys elution extraction Fuji Inc. Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples Novel coronavirus novel coronavirus disease novel coronavirus disease 2019 (COVID-19) Patient PCR PCR assay PCR test performed polymerase chain polymerase chain reaction positive Rapid diagnostic test RDT remained RNA RNA extraction Roche Diagnostics SARS-CoV SARS-CoV-2 SARS-CoV-2 antigen Science severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) System Takara Takara Bio virus [DOI] 10.1002/jmv.27709 PMC 바로가기 [Article Type] Article
Three SARS-CoV-2 PCR-negative cases of COVID-19 diagnosed using isothermal amplification methods등온 증폭법으로 진단된 코로나19 SARS-CoV-2 PCR 음성 사례 3건Article Published on 2022-07-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification Case report caused Chain Reaction coronavirus coronavirus disease costly COVID-19 COVID-19 patient diagnose diagnosed disease False negative false-negative false-negative results gold gold standard isothermal isothermal amplification isothermal amplification method isothermal amplification methods LAMP less Loop-mediated isothermal amplification Negative PCR nucleic acid nucleic acid amplification Patient PCR PCR test PCR tests PCR-negative performed polymerase chain polymerase chain reaction positive SARS-CoV-2 SARS-COV-2 infection Sensitivity and specificity severe acute respiratory syndrome Coronavirus test negative time-consuming viral disease [DOI] 10.1016/j.jiac.2022.04.002 PMC 바로가기 [Article Type] Article