Substitutions in PBP2b from β-Lactam-resistant Streptococcus pneumoniae Have Different Effects on Enzymatic Activity and Drug Reactivityβ-락탐 내성 폐렴구균의 PBP2b에서의 치환은 효소 활성 및 약물 반응성에 서로 다른 영향을 미친다.Article Published on 2017-02-172024-08-24 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] Antibiotic resistance cell wall enzyme kinetics peptidoglycan Streptococcus
Structural Comparison and Simulation of Pneumococcal Peptidoglycan Hydrolase LytBarticle Published on 2016-12-312024-09-01 Journal: Methods in molecular biology (Clifton, N.J.) [Category] 폐렴구균 감염증, [키워드] Hydrolytic activity assay LytB peptidoglycan Peptidoglycan hydrolase Simulation Streptococcus pneumoniae Structural comparison [Article Type] article
Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila초파리의 혈구에 의한 장 줄기 세포 활동의 원격 제어Research Article Published on 2016-05-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activate activated Activation activity Bacterial infection blood cell Blood cells canonical cell proliferation circulating contribute Control Coordinate Critical Defense Drosomycin Drosophila Express expression fat Gut haemocyte haemocytes Host receptors Immunity indicate induce Inflammation Injury Innate Interaction intestinal epithelium intestinal stem cell intestine involved JAK/STAT JAK/STAT pathway JNK pathway lipopolysaccharide liver mammals mode multiple tissues Mutation oral bacterial infection organ Organisms overcome pathway peptidoglycan Previous studies previous study proliferation promote recognize Regulation released remote required reveal secreted molecule secreted protein secreted proteins septic injury signaling pathway STAT STEM stem cell stimulate suggested survival systemic immune response tissue damage tissue repair turn Upd Upd1 Upd2 Upd3 Upds while wound [DOI] 10.1371/journal.pgen.1006089 PMC 바로가기 [Article Type] Research Article
Non-viable immunobiotic Lactobacillus rhamnosus CRL1505 and its peptidoglycan improve systemic and respiratory innate immune response during recovery of immunocompromised-malnourished mice비생존 면역 생물학적 락토바실러스 람노서스 CRL1505와 그 펩타이드글리칸은 면역 저하 및 영양 결핍 쥐의 회복 과정에서 전신 및 호흡기 선천 면역 반응을 개선합니다.journal-article Published on 2015-04-012024-08-04 Journal: International Immunopharmacology [Category] 폐렴구균 감염증, [키워드] Malnutrition Mucosal immunomodulators Non-viable Lactobacillus rhamnosus CRL1505 peptidoglycan Respiratory immunity. [DOI] 10.1016/j.intimp.2015.02.006 [Article Type] journal-article
Structural and biochemical analyses of theStreptococcus pneumoniaeL,D-carboxypeptidase DacB스트렙토코쿠스 뉴모니아의 L,D-카복시펩타이드 분해효소 DacB의 구조적 및 생화학적 분석journal-article Published on 2015-02-012024-08-04 Journal: Acta Crystallographica Section D Biological Crystallography [Category] 폐렴구균 감염증, [키워드] l,d-carboxypeptidase molecular docking peptidoglycan Streptococcus pneumoniae [DOI] 10.1107/S1399004714025371 [Article Type] journal-article
Structure of Pneumococcal Peptidoglycan Hydrolase LytB Reveals Insights into the Bacterial Cell Wall Remodeling and Pathogenesis폐렴구균 펩타이드글리칸 가수분해효소 LytB의 구조는 세균 세포벽 재구성 및 병원성에 대한 통찰력을 제공합니다.journal-article Published on 2014-08-012024-08-04 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] Bacterial pathogenesis Cell Wall Remodeling enzyme structure peptidoglycan Streptococcus structural biology [DOI] 10.1074/jbc.M114.579714 [Article Type] journal-article
Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold시아노티오펜 구조를 기반으로 한 두 번째 세대 MurF 억제제의 설계, 합성 및 평가journal-article Published on 2014-02-012024-08-04 Journal: European Journal of Medicinal Chemistry [Category] 폐렴구균 감염증, [키워드] antibacterials Enzyme inhibitors MurF peptidoglycan [DOI] 10.1016/j.ejmech.2013.11.031 [Article Type] journal-article
Direction of aminoacylated transfer RNAs into antibiotic synthesis and peptidoglycan‐mediated antibiotic resistance아미노아실화된 전이 RNA의 방향은 항생제 합성 및 펩티도글리칸 매개 항생제 저항에 관여한다.journal-article Published on 2013-09-172024-08-04 Journal: FEBS Letters [Category] 폐렴구균 감염증, [키워드] antibiotic Antibiotic resistance Pathogenesis peptidoglycan protein synthesis translation tRNA [DOI] 10.1016/j.febslet.2013.07.036 [Article Type] journal-article
Lipid II-independent trans Editing of Mischarged tRNAs by the Penicillin Resistance Factor MurM리피드 II-독립적인 미스차지된 tRNA의 페니실린 내성 인자 MurM에 의한 트랜스 편집journal-article Published on 2013-09-012024-08-04 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] Aminoacyl-tRNA Synthesis aminoacyl-tRNA synthetase peptidoglycan Transfer RNA (tRNA) translation [DOI] 10.1074/jbc.M113.479824 [Article Type] journal-article