Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition
GSK-3 억제를 통한 코로나바이러스 뉴클레오캡시드 단백질 표적화
Multicenter Study
[키워드] acute respiratory syndrome
Analysis
Antiviral
approach
Betacoronavirus
block
Clinical data
conducted
consensus sequence
consensus sequences
conserved
coronavirus
Coronavirus infection
Coronavirus infections
Coronaviruses
COVID-19
COVID-19 in patient
COVID19
Epidemics
epithelial cells
Express
glycogen
glycogen synthase
GSK-3
GSK3A
GSK3B
health system
Healthcare systems
human lung
human lung epithelial cells
impair
inhibitor
inhibitors
knockout
less
lithium
lithium use
lung epithelial cell
Middle East
Middle East respiratory syndrome
Middle East respiratory syndrome-CoV
motif
N protein
nucleocapsid
nucleocapsid protein
Odds ratio
Outbreaks
Patient
personal health
phosphorylated
Phosphorylation
raising
reduced risk
Replication
required
respiratory
responsible
Retrospective analysis
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 N protein
Severe acute respiratory syndrome
Significance
significantly
targeting
the SARS-CoV-2
therapy
Transcription
treat
Viral
viral replication
viral transcription
virion assembly
[DOI] 10.1073/pnas.2113401118 PMC 바로가기 [Article Type] Multicenter Study
[DOI] 10.1073/pnas.2113401118 PMC 바로가기 [Article Type] Multicenter Study