Staying InformED: Top emergency Medicine pharmacotherapy articles of 2020최신 정보 유지: 2020년 최고의 응급 의학 약물 요법 기사Review Published on 2021-11-012022-09-11 Journal: The American journal of emergency medicine [Category] SARS, 임상, [키워드] approach article articles clinician DelPhi Diagnosis Emergency emergency medicine identify management Medicine meta-analyses pandemic patients with COVID-19 pharmacotherapy provide review selected Trial [DOI] 10.1016/j.ajem.2021.05.061 PMC 바로가기 [Article Type] Review
Developing Cytokine Storm-Sensitive Therapeutic Strategy in COVID-19 Using 8P9R Chimeric Peptide and Soluble ACE2Cell and Developmental Biology Published on 2021-09-032022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] 8P9R chimeric peptide ACE2 ACE2 pathway Affect Anti-inflammatory ARDS chimeric clinical therapy CMV promoter COVID-19 COVID-19 pandemic Cytokine storm decrease Developing effective endosomal pH enzyme Exosomes expected expression host cell cytosol immune system increase Increases induce Inflammatory cytokine inflammatory genes inhibit inhibiting International lack M2 macrophages Mesenchymal stem cells morbidity and mortality NF-κB NF-κB organs pathway Pathways peptide pharmacotherapy Prevent pro-inflammatory promoter sACE2 sACE2 protein SARS-CoV-2 Strategy target cells the cytokine storm the disease the patient Therapies transcription factor Treatment treatment for COVID-19 treatment strategy viral replication virus virus entry [DOI] 10.3389/fcell.2021.717587 PMC 바로가기 [Article Type] Cell and Developmental Biology
Virological and genomic analysis of SARS-CoV-2 from a favipiravir clinical trial cohortfavipiravir 임상 시험 코호트에서 SARS-CoV-2의 바이러스 및 게놈 분석Randomized Controlled Trial Published on 2021-09-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 유전자 메커니즘, 임상, 치료제, [키워드] age China clade clinical study clinical trial Cohort collected conducted correlated CPE Cytopathic effect Daily disease onset distribution duration of symptoms Efficacy Europe Evidence evidence of examined Favipiravir followed by Genome Genome epidemiology genomes Genomic analysis hospital Japan majority Male sex median time Mutation nasopharyngeal specimen no evidence of one patient participated Patient pharmacotherapy randomization randomized clinical trial RdRP RdRp gene reducing reflected remained replacement reported RT-PCR SARS-CoV-2 SARS-CoV-2 genome sequenced significantly strain Strains the disease therapy Trial viability Viral load viral loads [DOI] 10.1016/j.jiac.2021.06.010 PMC 바로가기 [Article Type] Randomized Controlled Trial
The advantages of drug treatment with statins in patients with SARS-CoV-2 infectionReview Published on 2021-09-012023-07-02 Journal: Wiener Klinische Wochenschrift [Category] SARS, [키워드] Comorbidities hypercholesterolemia pandemic pharmacotherapy Pleiotropic effect. [DOI] 10.1007/s00508-021-01845-8 PMC 바로가기 [Article Type] Review
A Clinical Monitoring Program of COVID-19 Outpatients: A Prospective Cohort StudyResearch Article Published on 2021-07-202022-10-31 Journal: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale [Category] COVID-19, [키워드] Administered age C-reactive protein Characteristics clinical Clinical characteristics Clinical course clinical trial Comorbidity concerning contribute Coronavirus disease 2019 cough COVID-19 COVID-19 patient COVID-19 patients demographic demographics evaluated fatigue female Follow-up hemoglobin Hospitalization individual information laboratory data lymphocyte majority medication mild symptoms monitoring morbidity Mortality MOST myalgia Neutrophil-to-lymphocyte ratio no significant difference Observational cohort study onset of symptoms Patient patients pharmacotherapy Program Prospective recruited reduction required responsible Result severity significantly sore throat suffered Symptom symptom onset symptomatic Symptomatic patients Symptoms the patient variety was performed while White blood cell with COVID-19 [DOI] 10.1155/2021/6644570 PMC 바로가기 [Article Type] Research Article
Modulating the host immune response to fight against COVID-19: Where are we in 2021?Covid-19와의 싸움을위한 숙주 면역 반응 조절 : 2021 년 우리는 어디에 있습니까?Editorial Published on 2021-07-052022-09-10 Journal: Virulence [Category] SARS, 신약개발, 치료제, [키워드] coronavirus COVID-19 Drug repurposing Host immune response immune system immunology immunomodulation pharmacotherapy SARS-CoV-2 [DOI] 10.1080/21505594.2021.1943275 PMC 바로가기 [Article Type] Editorial
What the dental practitioner needs to know about pharmaco-therapeutic modalities of COVID-19 treatment: A reviewReview article Published on 2021-07-012022-10-05 Journal: Journal of Dental Sciences [Category] 치료법, 치료제, [키워드] adverse effect Analysis Anti-inflammatory Antibiotics Antiviral approved article association Azithromycin clinical trial complicate contribute Corticosteroids COVID-19 dental practice dental practitioner doxycycline drug effective expected highlight Hydroxychloroquine ibuprofen Immunomodulatory agent implication indication induce inflammatory conditions knowledge less material oral disease Pain Paracetamol Patient Pharmacotherapeutic pharmacotherapy practitioners Research Result SARS-CoV-2 therapeutic agents therapy treat Treatment Vaccine was performed while [DOI] 10.1016/j.jds.2020.11.007 [Article Type] Review article
Medication Use Among Patients With COVID‐19 in a Large, National Dataset: Cerner Real‐World Data™Research article Published on 2021-06-012022-10-05 Journal: Clinical therapeutics [Category] SARS, 신약개발, [키워드] age calculated Cerner clinician conducted coronavirus disease COVID-19 COVID-19 cohort COVID‐19 cross-sectional dataset demographic characteristics Demographic variables drug Drug prescriptions Factors female finding hospitalized patient Hydroxychloroquine include information Inpatient introduced knowledge mechanism medication National Older outbreak pandemic Patient patients with COVID-19 pharmacotherapy Practice patterns proportion provide required SARS-CoV-2 Sex stratified the timing the United State The United States therapeutic Tocilizumab Treatment treatment regimens variable Variation were used with COVID-19 [DOI] 10.1016/j.clinthera.2021.03.024 [Article Type] Research article
Machine Learning as a Precision-Medicine Approach to Prescribing COVID-19 Pharmacotherapy with Remdesivir or Corticosteroids렘데시비르 또는 코르티코스테로이드를 사용한 COVID-19 약물 요법 처방에 대한 정밀 의학 접근 방식으로서의 기계 학습Article Published on 2021-05-012022-09-11 Journal: Clinical therapeutics [Category] 신약개발, 치료제, [키워드] adjust Adult patients adverse effects age Algorithm Algorithms benefit clinical guideline coronavirus disease coronavirus disease-2019 Corticosteroid Corticosteroids COVID-19 COVID-19 crisis Electronic health record Electronic health records evaluated Gray hazard ratio hazard ratios help hospitalizations hospitalized patient hospitalized patients hospitals identify IMPROVE increase in increased survival inverse knowledge machine machine learning machine-learning men Model outcome oxygen Patient patients pharmacotherapy Population prescribing recent Remdesivir resource resources SARS-CoV-2 significantly subpopulation subset supplemental oxygen supported survival survival time tested treated Treatment treatment of COVID-19 use of corticosteroid were used with COVID-19 [DOI] 10.1016/j.clinthera.2021.03.016 PMC 바로가기 [Article Type] Article
Cardiovascular Complications of COVID-19: Pharmacotherapy PerspectiveCOVID-19의 심혈관 합병증: 약물 요법의 관점Review Published on 2021-04-012022-09-11 Journal: Cardiovascular Drugs and Therapy [Category] SARS, 치료제, [키워드] 2019 Acute coronary syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered anti-inflammatory agents approved Arrhythmias cardiovascular cardiovascular complication cardiovascular complications cardiovascular disease caused Complication coronary syndrome coronavirus coronavirus disease COVID-19 COVID-19 infection Dexamethasone disease drug Drug–drug interactions Evidence Health Organization healthy individual heart failure Hydroxychloroquine increased risk Interaction medication morbidity Mortality myocarditis Patient patients with COVID-19 pharmacotherapy problem protease inhibitors Remdesivir SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 severe acute respiratory syndrome Coronavirus therapy Thromboembolism Treatment Venous Thromboembolism World Health Organization [DOI] 10.1007/s10557-020-07037-2 PMC 바로가기 [Article Type] Review