Phylogenomics – Page 3 – Communicable Diseases Research

Comparative Genomics and Integrated Network Approach Unveiled Undirected Phylogeny Patterns, Co-mutational Hot Spots, Functional Cross Talk, and Regulatory Interactions in SARS-CoV-2

Research Article

Published on 2021-02-232022-10-29
Journal: mSystems [Category] COVID-19,

[키워드] ACE2 acute respiratory syndrome affected affecting Amino acid Analysis angiotensin-converting enzyme 2 Antiviral binding caused clade co-occurrence Combination Comparative Comparative genomics Complete condition conditions contributing to coronavirus coronavirus disease country COVID-19 CpG D614G effective FIVE full-length genome functional annotation Genome Genomics geographical region highlighting host cell host proteins host-pathogen interaction hypoxia inhibiting Interaction membrane Mutation mutational studies MYO5A MYO5B MYO5C network network analysis novel nucleocapsid ORF8 pandemic pathogenicity pathway patients Phylogenomics Phylogeny polymorphism predicted Protein protein stability Proteins provided rate of infection receptor reduction in Region SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection SARS-CoV-2 virus screened Severity of infection single nucleotide SNP Spike protein strain Strains structural biology suggested the United State The United States thrombotic TMPRSS2 translation Transmissibility Transmission Treatment Variation Viral protein ZAP
[DOI] 10.1128/mSystems.00030-21 PMC 바로가기 [Article Type] Research Article

Phylogenomics reveals viral sources, transmission, and potential superinfection in early-stage COVID-19 patients in Ontario, Canada

Phylogenomics는 캐나다 온타리오주에서 초기 단계의 COVID-19 환자에서 바이러스 소스, 전염 및 잠재적 중복 감염을 밝혀냅니다.

Article

Published on 2021-02-122022-09-01
Journal: Scientific Reports [Category] MERS, 변종, 유전자 메커니즘, 진단, 치료기술,

[키워드] Analysis Canada carried Cohort Community complement Contact tracing D614G Diseases early stages early-stage COVID-19 Effectiveness Epidemiology event Evolutionary biology filtered Genome Genome evolution GISAID database help heterozygous variant heterozygous variants IMPROVE Infectious disease International Ion limit MinION Missense Molecular epidemiology nasopharyngeal swabs Next-generation sequencing Pandemics pathogenicity Patient Phylogenetic analysis phylogenetics Phylogenomics platform Point mutation polymorphic site positive Public health intervention reveal SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes sequenced Sequencing Spike protein Spread Surveillance Swab synonymous variant the SARS-CoV-2 the spike protein Transmission Travel Viral viral genomes viral infection viral strain
[DOI] 10.1038/s41598-021-83355-1 PMC 바로가기 [Article Type] Article

VERSO: A comprehensive framework for the inference of robust phylogenies and the quantification of intra-host genomic diversity of viral samples

Article

Published on 2021-01-282022-10-28
Journal: Patterns [Category] COVID-19,

[키워드] Abstract acute respiratory syndrome Analysis approach Cluster co-occurrence condition consensus sequences Contact tracing coronavirus COVID-19 COVID-19 pandemic data-driven dataset diffusion epidemiological Evolution Evolution of SARS-CoV-2 explain Frequency genomic Genomic surveillance highlight homoplasies homoplastic variants identify IMPROVE Infection infection chain Intra-host diversity intra-host genomic diversity involved joint limitation limitations mutations outperform pathogen phylogenetic inference Phylogenomics Phylogeny platform Positive selection predict profiles quantification raw sequencing data Research reveal RNA sequencing robust SARS-CoV-2 SARS-CoV-2 consensus sequence SARS-CoV-2 evolution selected sequencing data spike gene Surveillance variant viral evolution viral genomes viral sample Viral variants
[DOI] 10.1016/j.patter.2021.100212 PMC 바로가기 [Article Type] Article

Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2, Colombia

중증급성호흡기증후군 코로나바이러스 2의 유전체 역학, 콜롬비아

Research

Published on 2020-12-012022-09-10
Journal: Emerging Infectious Diseases [Category] MERS, SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 causative agent clinical sample collected Colombia complement coronavirus coronavirus 2 coronavirus disease country COVID-19 COVID-19 outbreak diagnosed disease epidemiologically Europe events Evidence evidence of genome sequence Genome sequencing highlight investigated Italy Lineage lineages Phylogenetic Phylogenomics provide respiratory respiratory infections SARS SARS-CoV-2 sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Support Transmission Travel viruses zoonoses
[DOI] 10.3201/eid2612.202969 PMC 바로가기 [Article Type] Research

Phylogenomics and phylodynamics of SARS-CoV-2 genomes retrieved from India

Short Communication

Published on 2020-11-302022-10-31
Journal: Future Virology [Category] COVID-19,

Whole-genome epidemiology links phage-mediated acquisition of a virulence gene to the clonal expansion of a pandemic Salmonella enterica serovar Typhimurium clone

전체 유전체 역학은 파지 매개로 virulence 유전자의 획득을 팬데믹 살모넬라 엔테리카 세로바르 타이피무리움 클론의 클론 확장과 연결합니다.

Article

Published on 2020-11-282024-07-29
Journal: Microbial Genomics [Category] 살모넬라증,

[키워드] Epidemic Evolution Phylogenomics Salmonella sopE
[DOI] 10.1099/mgen.0.000456 PMC 바로가기

Phylogenomics Analysis of SARS-CoV2 Genomes Reveals Distinct Selection Pressure on Different Viral Strains

Research Article

Published on 2020-11-272022-10-27
Journal: BioMed Research International [Category] Coronavirus, MERS, SARS,

Phylogeography of 27,000 SARS-CoV-2 Genomes: Europe as the Major Source of the COVID-19 Pandemic

Article

Published on 2020-10-292022-10-29
Journal: Microorganisms [Category] COVID-19,

Non-synonymous mutations of SARS-CoV-2 leads epitope loss and segregates its variants

Original Article

Published on 2020-10-102023-06-15
Journal: Microbes and infection [Category] MERS, SARS,

[키워드] COVID-19 Epitope loss Non-synonymous mutation Phylogenomics SARS-CoV-2
[DOI] 10.1016/j.micinf.2020.10.004 PMC 바로가기 [Article Type] Original Article

Accommodating individual travel history and unsampled diversity in Bayesian phylogeographic inference of SARS-CoV-2

Article

Published on 2020-10-092022-10-04
Journal: Nature Communications [Category] MERS, SARS, 유전자 메커니즘,