plasmacytoid dendritic cells

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 addition against SARS-CoV animal models antiviral molecules boost caused cells characterized clinical trial Combination complex interplay conserved conserved IFN evasion strategies contribute coronavirus coronavirus epidemic Coronavirus-2 counteraction COVID-19 COVID-19 pandemic Cytokines dendritic cells early stage early stages Efficacy exacerbated form highlighting IFN IFN treatment IFN-I IFN-I response IFN-I treatment IFN-Is immune response interferons knowledge mechanism MERS MERS-CoV Middle East Middle East respiratory syndrome Middle East respiratory syndrome-related coronavirus molecular mechanisms outbreak pDC-mediated IFN response pDC-mediated IFN responses pDCs plasmacytoid dendritic cell plasmacytoid dendritic cells potential benefit potential benefits proinflammatory cytokines respiratory responsible SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2–infected cells Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 spatiotemporal regulation the disease therapeutic type I interferon type I interferons Viral viral infection while
[DOI] 10.1371/journal.ppat.1008737 PMC 바로가기 [Article Type] Review