Nanoparticles as Adjuvants and Nanodelivery Systems for mRNA-Based VaccinesReview Published on 2020-12-302022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] acting adjuvant administration Cancer clinical trial Diseases ENhance evaluated Immune cell immune system Immunological response IMPROVE in vivo inefficient Infectious disease lipids messenger microorganism mRNA mucosal Nanodelivery systems nanoparticle Nanoparticles natural infection Non-invasive polymers profiles Prophylactic reducing RNA shown similarity System therapeutic vaccination Vaccine Vaccines [DOI] 10.3390/pharmaceutics13010045 PMC 바로가기 [Article Type] Review
An Overview on Personal Protective Equipment (PPE) Fabricated with Additive Manufacturing Technologies in the Era of COVID-19 PandemicArticle Published on 2020-11-162022-10-28 Journal: The British journal of oral & maxillofacial surger [Category] COVID-19, [키워드] 3D printing Additive Additive manufacturing Care carried caused Characteristics coronavirus 2 coronavirus disease COVID-19 determine disease effective estimation evaluated explained Face mask fused highlighting information mechanical testing no significant effect Open-source model performed Personal protective equipment PLA polyamide polymers potential risk PPE provided recommendation remote medicine respiratory SARS-CoV-2 selective Spectrophotometry stability Sterilization technology virus [DOI] 10.3390/polym12112703 PMC 바로가기 [Article Type] Article
A new generation of vaccines based on alphavirus self-amplifying RNAReview article Published on 2020-10-012022-10-05 Journal: Current opinion in virology [Category] SARS, 비임상, [키워드] Administered alphavirus Antigen approach Cationic lipid cellular response clinical trial conventional vaccine DNA Electroporation expression vector high expression level humoral Immunity in vivo induce initiated mRNA mRNA vaccine Pathogens polymers profiles responses RNA SARS-CoV-2 shown vaccinate Vaccine viral particle [DOI] 10.1016/j.coviro.2020.08.003 [Article Type] Review article
Antiviral Potential of Nanoparticles—Can Nanoparticles Fight Against Coronaviruses?Review Published on 2020-08-212022-10-30 Journal: Nanomaterials [Category] COVID-19, [키워드] accelerate acute respiratory syndrome Against Antiviral antiviral agent Antiviral agents antiviral drug Antiviral mechanism antiviral therapies antiviral therapy can be used caused coronavirus coronavirus disease COVID-19 COVID-19 pandemic death deaths disease drug resistance Effect global mortality Health help host cell include individual mechanism mechanisms MERS Middle East mitigate nanoparticle pandemic Perspective polymers Potential Prevent Probability provide responsible SARS-CoV-2 Spread syndrome Therapeutic approach therapeutic approaches treat Treatment Vaccine viral disease viral infections viral mechanism of entry virus [DOI] 10.3390/nano10091645 PMC 바로가기 [Article Type] Review
Biofilm-associated toxin and extracellular protease cooperatively suppress competitors in Bacillus subtilis biofilms생물막 관련 독소 및 세포외 프로테아제는 Bacillus subtilis 생물막에서 경쟁자를 협력적으로 억제합니다Research Article Published on 2019-10-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] aggregate Alter antibiotic Antibiotics Antimicrobials assistance B . subtilis Bacillus subtilis Bacteria Bacterial bacterial composition biofilm Cell cells combating contribute Defense DEGs demonstrated diffusion Diseases effective eliminated excluded expression Extracellular food contamination growth impair Infectious diseases inhibit leads medium multicellular mutant mutations Neutral observation overexpression penetrate peptide Polymer polymers Prevent problem problems protease PROTECT Protein Regulatory required resistance gene resistance genes secreted solid medium Space suppress Taking Tolerance Treatment type strain upstream wild-type strain [DOI] 10.1371/journal.pgen.1008232 PMC 바로가기 [Article Type] Research Article
Polyamidoamine nanoparticles as nanocarriers for the drug delivery to malaria parasite stages in the mosquito vectorArticle Published on 2015-11-302024-09-10 Journal: Nanomedicine (Lond) [Category] 말라리아, [키워드] Anopheles Antimalarial drugs malaria mosquitoes nanomedicine Nanotechnology Plasmodium polyamidoamines polymers Targeted drug delivery PMC 바로가기
Toy kit against malaria: magic bullets, LEGO, Trojan horses and Russian dollsarticle Published on 2014-10-312024-09-01 Journal: Ther Deliv [Category] 말라리아, [키워드] antimalarial heparin magic bullet malaria nanomedicine Nanotechnology nanovector Plasmodium polymers Targeted drug delivery [Article Type] article
Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone MachinesHsp40s는 Hsp104 및 Hsp90 단백질 샤페론 기계의 기능을 지정합니다Research Article Published on 2014-10-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activities activity alteration amplification Bacterial C-terminal C-terminal domain Cell cellular chaperone chaperones competing complement complex complexes component conformation cooperation domain explain function functional functions growth help Hsp70 increasingly Interaction less machine maintain microorganism microorganisms overexpressed overexpressing plant plants polymers promote Propagation PROTECT Protein Proteins PSI regulate Regulation Replication respond specific activities Stress Support thermotolerance underlie yeast [DOI] 10.1371/journal.pgen.1004720 PMC 바로가기 [Article Type] Research Article
Synthesis, characterization, and antiplasmodial activity of polymer-incorporated aminoquinolinesarticle Published on 2014-06-302024-09-01 Journal: Journal of Biomedical Materials Research Part A [Category] 말라리아, [키워드] aminoquinoline antimalarial Plasmodium falciparum polymers [Article Type] article
Advances in nanomedicines for malaria treatmentArticle Published on 2013-12-312024-09-10 Journal: Adv Colloid Interface Sci [Category] 말라리아, [키워드] 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine absorption, distribution, metabolism and excretion Act ADME AFM Ag NPs area under the plasma level-time curve artemisin combination therapy Atomic force microscopy AUC CCRD central composite rotable design CHOL cholestrol Colloidal carriers DBPC dendrimers DEP DHA dibenhenoyl phosphatidylcholine Dielectrophoresis differencial scanning calorimetry dihydroartemisinin dimyristoyl phosphatidylcholine dimyristoyl phosphatidylglycerol dipalmitoyl phosphatidylcholine dipalmitoyl phosphatidylglycerol distearoyl phosphatidylcholine distearoyl phosphatidylglycerol distearoyl phosphoethanolamine DL DLS DMPC DMPG DNDi DOPC DPPC DPPG drug loading Drugs for Negleted Diseases initiate DSC DSPC DSPE DSPG dynamic light scattering EE egg phosphatidylcholine egg phosphatidylglycerol encapsulation efficiency EPC EPG FACS FFF field-flow-fractionation fluorescence activated cell sorting food vacuole membrane Fourier transformed infrared spectroscopy FTIR FVM HCM host red cell membrane HPMC HPβCD hydroxyl propyl methyl cellulose hydroxypropyl-β-cyclodextrin ICT immune chromatographic tests Institute for One World Health IOWH LC lipids liposomes loading capacity malaria MCT Medicine for malaria venture medium chain triglyceride Micro analysis systems Microfluidics mitochondrial membrane MM MMV nanomedicine Nanostructured lipid carriers new permeation pathways NLC NMR NPP nuclear magnetic resonance ODNs oligodeoxynucleotides PACA parasite plasma membrane PC PCQD PCS PE PG Phosphatidylcholine phosphatidylethanolamine phosphatidylglycerol photon correlation spectroscopy Plasmodium PLGA poly (d,l-lactide-co-glycolide) polyalkylcyanoacrylates polymers polypropyleneimine polyvinyl pyrrolidon positively charged qdots PPI PPM PVP RBC RBCM red blood cell red blood cell membrane response surface methodology RSM scanning electron microscopy self-micro emulsifying drug delivery systems SEM Silver nanoparticles SLN SMEDDS Solid lipid nanoparticles TEM TNF-α Toxicity transmission electron microscopy tubovesicular membrane tumor necrosis factor-α TVM WBC White blood cell μTAS. PMC 바로가기