The necessity of incorporating non-genetic risk factors into polygenic risk score modelsarticle Published on 2023-02-202024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Cancer cardiovascular diseases diabetes Diseases Endocrine system and metabolic diseases genetics Population genetics Risk factors [DOI] 10.1038/s41598-023-27637-w PMC 바로가기 [Article Type] article
Population genetic analysis of Plasmodium knowlesi reveals differential selection and exchange events between Borneo and Peninsular sub-populations플라스모디움 노울레시의 인구 유전학적 분석은 보르네오와 반도체 아시아 하위 집단 간의 차별적 선택 및 교환 사건을 드러냅니다.Article Published on 2023-02-072024-08-01 Journal: Burma Med J [Category] 말라리아, [키워드] Genetic variation Population genetics [DOI] 10.1038/s41598-023-29368-4 PMC 바로가기
Geographical distribution of cystic fibrosis carriers as population genetic determinant of COVID-19 spread and fatality in 37 countries37개국에서 COVID-19 확산 및 사망률의 인구 유전적 결정인자인 낭포성 섬유증 보균자의 지리적 분포Article Published on 2022-09-012022-09-11 Journal: The Journal of Infection [Category] Fulltext, MERS, 변종, 유전자 메커니즘, 진단, [키워드] affected Cancer carrier carriers Case fatality rate CF carriers CFR CFTR Conductance conducted correlated country COVID-19 Cystic cystic fibrosis determine distribution ecological Ecological study Factor fatality fibrosis Genetic genetics geographical distribution heterogeneity higher risk Host Indicator Mortality multivariate Older pandemic pathogenic variant pathogenicity performed Population genetics positively correlated Prevalence Rate Regression model regulator respiratory tract infection Respiratory tract infections SARS-CoV-2 severe COVID-19 shown significantly Spread subject susceptible undergo Variability Weighting [DOI] 10.1016/j.jinf.2022.06.006 PMC 바로가기 [Article Type] Article
Tracking of SARS-CoV-2 Alpha variant (B.1.1.7) in Palestine팔레스타인에서 SARS-CoV-2 알파 변종(B.1.1.7) 추적Article Published on 2022-07-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant Analysis analyzed B.1.1.7 bootstrap clade Cluster collected COVID-19 COVID-19 mortality COVID-19 pandemic Diagnosis disease severity effective F-statistic gene flow Genetic variation genetics genome sequence homogenous Hypothesis impacted introduced Nablus new SARS-CoV-2 Palestine peaked Phylogenetic tree Population genetics remains uncertain replaced SARS-CoV-2 SARS-CoV-2 surveillance SARS-CoV-2 variants sequenced statistically statistically significant supported Tajima therapy Transmission Vaccine-induced immunity variant virulence WGS whole genome sequence wild type [DOI] 10.1016/j.meegid.2022.105279 PMC 바로가기 [Article Type] Article
Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other LineagesCOVID-19 환자의 비인두 샘플에서 SARS-CoV-2 분석은 다른 계통과 관련하여 우려되는 변이체의 성장 특성을 배치하여 인구 변이 및 다양한 표현형을 보여줍니다Article Published on 2022-06-292022-09-11 Journal: mSphere [Category] COVID19(2023년), SARS, 변종, [키워드] A549 cells Alpha amplified Beta Beta variant Biology biology of SARS-CoV-2 causative agent Cell Cell culture cell line cells change characterized clinical isolates clinical samples concern Context coronavirus COVID-19 Delta disease effective Evolution genetic diversity genetics genome sequence genomic global pandemic growth growth kinetics hACE2 hospitalized patient hospitalized patients humans immune evasion increased risk indicated Infection isolate isolates less Lineage minor minor genomic variants morbidity Mortality Nasopharyngeal swab nasopharyngeal swabs New no difference not different omicron Other other coronaviruses other variant other variants pandemic patients pattern planet Population Population dynamics Population genetics Postinfection preserved property Research RNA RNA sequencing Sample SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes sequence several variants Spread suggested Transmission vaccination Vaccine Variability variant variants variants of concern variants of SARS-CoV-2 Variation Vero E6 Vero E6 cell VERO E6 cells virus Virus evolution VoC VOCs widespread with COVID-19 [DOI] 10.1128/msphere.00913-21 PMC 바로가기 [Article Type] Article
Human herpesvirus diversity is altered in HLA class I binding peptidesBiological Sciences Published on 2022-04-292024-09-04 Journal: Proceedings of the National Academy of Sciences of [Category] 대상포진, [키워드] EBV HCMV herpesvirus HLA Population genetics [DOI] 10.1073/pnas.2123248119 PMC 바로가기 [Article Type] Biological Sciences
Forecasting emergence of COVID-19 variants of concernCovid-19의 관심의 변형의 출현 예측Research Article Published on 2022-02-242022-09-10 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, [키워드] COVID-19 defined Forecasting genetics identify increase in Infectious disease outbreak Pandemics Population genetics Spread the SARS-CoV-2 variants variants of concern Variation Viral [DOI] 10.1371/journal.pone.0264198 PMC 바로가기 [Article Type] Research Article
Molecular epidemiology and population genomics of Plasmodium knowlesiarticle Published on 2021-12-312024-09-01 Journal: Advances in parasitology [Category] 말라리아, [키워드] emerging infection genome sequence genotyping Microsatellites mitochondrial DNA Population genetics [Article Type] article
Estimating the strength of selection for new SARS-CoV-2 variants새로운 SARS-CoV-2 변종에 대한 선택 강도 추정Article Published on 2021-12-142022-09-10 Journal: Nature Communications [Category] SARS, 변종, 유전자 메커니즘, [키워드] (Alpha) (Beta) Alpha Analysis B.1.1.7 B.1.351 Beta controlling country Cutting D614G determine develop drift Epidemiology estimate evaluate Evidence Frequency Genetic variant heterogeneity human host identifying include increasingly Japan magnitude methodology Migration Molecular epidemiology new SARS-CoV-2 pandemic Perspective Population genetics public health reveal SARS-CoV-2 SARS-CoV-2 pandemic selective spike mutation Spread strength the SARS-CoV-2 transmissible variants variant variants variants of SARS-CoV-2 viral infection virus [DOI] 10.1038/s41467-021-27369-3 PMC 바로가기 [Article Type] Article
Microorganisms as Shapers of Human Civilization, from Pandemics to Even Our Genomes: Villains or Friends? A Historical ApproachReview Published on 2021-12-062022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Yersinia pestis addition Antibiotics Bacteria Biotechnology Black Death caused characterized Civilization Compound contributed coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic develop DNA drug endogenous endogenous retrovirus Europe Evolution Factors Gene Expression genetics groups gut microbiota help Human Influenza microbiota microorganism Mortality Pandemics plague Population genetics Regulation responsible SARS-CoV-2 significantly Spanish flu survival Universal Villain [DOI] 10.3390/microorganisms9122518 PMC 바로가기 [Article Type] Review