An isothermal lab-on-phone test for easy molecular diagnosis of SARS-CoV-2 near patients and in less than 1 hourArticle Published on 2022-10-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] amplification B.1.1.529 B.1.351 B.1.617.2 Beta Clinical management clinical samples conducted COVID-19 COVID-19 pandemic cross-reaction Delta demonstrated e genes gold standard Infection isothermal isothermal amplification LAMP assay less Molecular diagnosis nasopharyngeal nucleic acid amplification techniques omicron Patient point of care point-of-care point-of-care testing Population screening predominant Real-time PCR respiratory pathogen SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant sensitivity specificity Symptom Transmission Volunteer [DOI] 10.1016/j.ijid.2022.07.042 PMC 바로가기
Dynamics of anti-SARS-CoV-2 seroconversion in individual patients and at the population levelArticle Published on 2022-09-092022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibody antibody production Asymptomatic Care COVID-19 demonstrated determine diagnosed Dynamics fraction Health hidden highest highlighting immune response Immunity individual infected with SARS-CoV-2 Infection key factor levels of antibodies Mild observation occurred pandemic Pandemics participant Patient Perspective Poland population level Population screening positive predict Registered SARS-CoV-2 SARS-COV-2 infection Seroconversion specific antibody suppress Trajectories Vaccinations [DOI] 10.1371/journal.pone.0274095 PMC 바로가기
A How to Guide: Clinical Population Test Development and Authorization of MALDI-ToF Mass Spectrometry-Based Screening Tests for Viral InfectionsArticle Published on 2022-09-032022-11-15 Journal: Viruses [Category] 치료기술, [키워드] applied Applying Asymptomatic asymptomatic screening authorization Bacteria Bacterial CLIA CLIA-LDT clinical clinical process clinical testing COVID-19 criteria detection development diagnostic fungi Infection Laboratory limits MALDI-TOF MS mass MS test overcome pathogenic Population Population screening Proteins regulatory authority SAR-CoV-2 SARS-CoV-2 Screening Systems biology Test viral infection viral infections Viral protein virus viruses [DOI] 10.3390/v14091958 PMC 바로가기
A non-invasive ultrasensitive diagnostic approach for COVID-19 infection using salivary label-free SERS fingerprinting and artificial intelligenceResearch article Published on 2022-09-012022-10-05 Journal: Journal of photochemistry and photobiology. B, Bio [Category] SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Accuracy approach artificial intelligence biochemical change Classifier clinical COVID-19 COVID-19 infected patient COVID-19 infection COVID-19 outbreak demonstrated Diagnosis diagnostic diagnostics Efficiency false-negative genetic diversity global healthcare gold standard healthy healthy control high accuracy invasive Label-free limit Machine learning algorithms management MERS-CoV Mutation Nasopharyngeal swab Non-invasive Patient Population screening positive predicted reagents risk Saliva salivary SARS-CoV SARS-CoV-2 SARS-COV-2 infection scattering sensitivity specificity Stage subjects Support surface enhanced Raman spectroscopy SVM the patient virus virus spike protein [DOI] 10.1016/j.jphotobiol.2022.112545 [Article Type] Research article
Identifying SARS-CoV-2 Variants of Concern through Saliva-Based RT-qPCR by Targeting Recurrent Mutation Sites재발 돌연변이 부위를 표적으로 하여 타액 기반 RT-qPCR을 통해 우려의 SARS-CoV-2 변이체 식별Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Accuracy antibody approach characterized clinical methods complement concern COVID-19 demonstrated diagnostic diagnostics E484K Efficacy Genetic identify identifying influence investigated L452R Mask mandates Mutation nucleotides omicron performed Population screening positive probe public health public health threat qPCR qPCR assays quarantine Real-time monitoring recommendation Recurrent RNA RT-qPCR RT-qPCR assay Saliva saliva samples SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variant SARS-CoV-2 variants screened selective Sequencing single nucleotide Site SNP South Spread Surveillance targeting Transmissibility treatment regimens variants variants of concern VoC VOCs whole genome whole genome sequence Whole genome sequencing [DOI] 10.1128/spectrum.00797-22 PMC 바로가기 [Article Type] Article
Ultrasensitive Detection of COVID-19 Virus N Protein Based on p-Toluenesulfonyl Modified Fluorescent Microspheres Immunoassayp-톨루엔설포닐 변형 형광 미소구 면역분석법을 기반으로 한 COVID-19 바이러스 N 단백질의 초고감도 검출Article Published on 2022-06-222022-09-11 Journal: Biosensors [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] addition antibody buffer capture caused coronary pneumonia COVID-19 COVID-19 N protein COVID-19 virus detect detection Detection limit Fc region fluorescent fluorescent microspheres group hydrophobic immunochromatographic immunochromatographic assay Infection ionic strength Lateral lateral flow lateral flow immunochromatographic assay LFIA Ligand Mortality N protein p-toluenesulfonyl. pandemic Pneumonia Population screening promote reactive reactivity strip sulfhydryl tosyl [DOI] 10.3390/bios12070437 PMC 바로가기 [Article Type] Article
Verification of lateral flow antigen tests for SARS-CoV-2 by qPCR directly from the test device검사기기에서 직접 qPCR로 SARS-CoV-2에 대한 측면유동항원 검사 확인Article Published on 2022-06-012022-09-11 Journal: Dental materials : official publication of the Aca [Category] COVID19(2023년), SARS, 치료기술, [키워드] added amplification Antigen clinical settings Cobas Liat cohorts complex coronavirus dental Dental clinical safety equipment extraction False negative false negative results False positive ID NOW Infection Laboratory Lateral lateral flow Lateral flow antigen test (LFAT) management nucleic acid nucleic acid amplification pandemic Patient PCR point of care Population screening positive qPCR Rapid Rapid antigen tests Reactions reliability SARS-CoV-2 SARS-CoV-2 pandemic sensitivity serial dilution solution speed subsequent Test Test strategy. the SARS-CoV-2 Usage verification was performed [DOI] 10.1016/j.dental.2022.03.005 PMC 바로가기 [Article Type] Article
RT-qPCR-based tests for SARS-CoV-2 detection in pooled saliva samples for massive population screening to monitor epidemics전염병 모니터링을 위한 대규모 인구 스크리닝을 위한 혼합 타액 샘플에서 SARS-CoV-2 검출을 위한 RT-qPCR 기반 테스트Article Published on 2022-05-162022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] approach Asymptomatic individuals clinical sample clinical samples costly Ct values detect diagnostic diagnostic test diagnostics Epidemics False negative False positive FIVE gold gold standard infected individuals isolated RNA IVD MONITOR PCR testing pooling Population screening populations positive Probability Prophylactic qPCR test reached RNA RT-PCR testing RT-qPCR RT-qPCR test Saliva saliva samples SARS-CoV-2 detection SARS-CoV-2 infections screening test sensitivity side specificity subsequent Swab SYBR Green Testing throughput viral genome within 6 months [DOI] 10.1038/s41598-022-12179-4 PMC 바로가기 [Article Type] Article
Molecularly Imprinted Polymer Nanoparticles Enable Rapid, Reliable, and Robust Point-of-Care Thermal Detection of SARS-CoV-2분자 각인 고분자 나노 입자로 SARS-CoV-2의 신속하고 신뢰할 수 있으며 강력한 현장 진료 열 감지 가능Article Published on 2022-04-222022-09-11 Journal: ACS Sensors [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] Acidic addition affinity Alpha amino acids antibody Antigen biosensors condition COVID-19 detection Detection limit diagnostic diagnostic testing elevated temperature epitope heat heat transfer heat transfer method (HTM) lack media molecularly imprinted polymer nanoparticles (nanoMIPs) nanoparticle Patient point-of-care point-of-care testing Polymer Population screening Rapid rapid antigen test Rapid antigen tests receptors SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antigens sensitivity Sensitivity and specificity Spike protein temperature the spike protein thermal transfer variant variants [DOI] 10.1021/acssensors.2c00100 PMC 바로가기 [Article Type] Article
Assessment of Saliva Specimens’ Reliability for COVID-19 SurveillanceCOVID-19 감시를 위한 타액 표본의 신뢰성 평가Article Published on 2022-04-042022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis assessment Community Concordance coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 screening diagnostic diagnostics Follow-up Follow-up analysis gene target investigated Mass screening nasopharyngeal Nasopharyngeal swab NP swab Pathogenesis Population screening real-time RT-PCR reliability reverse transcription-PCR RT-PCR RT-PCR assay Saliva saliva samples salivary SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus specimen Support Swab tested the SARS-CoV-2 virus Transmission [DOI] 10.3389/fpubh.2022.840996 PMC 바로가기 [Article Type] Article