COVID-19: Omicron – the latest, the least virulent, but probably not the last variant of concern of SARS-CoV-2COVID-19: 오미크론 - 최신, 가장 덜 독성이지만 SARS-CoV-2의 우려의 마지막 변종은 아닐 것입니다.Review Published on 2022-07-012022-09-11 Journal: Microbial Biotechnology [Category] COVID19(2023년), SARS, 변종, [키워드] affected Antibody Response Antiviral booster breadth cell entry Cellular immune response convalescent patient Convalescent patients COVID-19 pandemic Delta demonstrated dominant Endocytic pathway experiment explain fusion hamsters Immune escape immunization Infection intrinsic less Lineage Lung function mainstream mice monoclonal antibodies mutated Mutation neutralization omicron Omicron variant plasma membrane population immunity preserved question raising Replication respiratory tract SARS-CoV-2 SARS-CoV-2 strain serum antibodies serum antibody Severe infection severe infections South Africa Spike protein the spike protein therapeutic titre trajectory Transmission vaccinee vaccinees variant virulence virulent VoC widespread [DOI] 10.1111/1751-7915.14064 PMC 바로가기 [Article Type] Review
Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other LineagesCOVID-19 환자의 비인두 샘플에서 SARS-CoV-2 분석은 다른 계통과 관련하여 우려되는 변이체의 성장 특성을 배치하여 인구 변이 및 다양한 표현형을 보여줍니다Article Published on 2022-06-292022-09-11 Journal: mSphere [Category] COVID19(2023년), SARS, 변종, [키워드] A549 cells Alpha amplified Beta Beta variant Biology biology of SARS-CoV-2 causative agent Cell Cell culture cell line cells change characterized clinical isolates clinical samples concern Context coronavirus COVID-19 Delta disease effective Evolution genetic diversity genetics genome sequence genomic global pandemic growth growth kinetics hACE2 hospitalized patient hospitalized patients humans immune evasion increased risk indicated Infection isolate isolates less Lineage minor minor genomic variants morbidity Mortality Nasopharyngeal swab nasopharyngeal swabs New no difference not different omicron Other other coronaviruses other variant other variants pandemic patients pattern planet Population Population dynamics Population genetics Postinfection preserved property Research RNA RNA sequencing Sample SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes sequence several variants Spread suggested Transmission vaccination Vaccine Variability variant variants variants of concern variants of SARS-CoV-2 Variation Vero E6 Vero E6 cell VERO E6 cells virus Virus evolution VoC VOCs widespread with COVID-19 [DOI] 10.1128/msphere.00913-21 PMC 바로가기 [Article Type] Article
Impact of previous cardiac function status assessed by echocardiography on the outcome of COVID-19 Research Published on 2022-06-232022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료법, [키워드] age analyzed anticoagulation association average cardiac function cardiovascular risk factor Clinical characteristics clinical factor COVID-19 Deceased demographic data diastolic died disease Echocardiogram echocardiographic echocardiographic parameter Ejection fraction Factor fatality First wave Gender identify Impact in both groups in-hospital mortality increased mortality individuals information left LVEF male occurred outcome parameter Patient performed predictor preserved prognostic receiving regression analysis ROC Curve SARS-COV-2 infection significant difference significantly significantly lower Spain therapy variable ventricular was performed [DOI] 10.1038/s41598-022-14887-3 [Article Type] Research
Detection of Ancient Viruses and Long-Term Viral Evolution고대 바이러스의 탐지 및 장기간의 바이러스 진화Review Published on 2022-06-182022-09-11 Journal: Viruses [Category] 치료기술, [키워드] analyzed ancient DNA ancient RNA ancient virome ancient virus approach bioinformatics complex COVID-19 outbreak detectable detection events human population NGS Pandemics past pathogenic pathogenic virus pathogenic viruses PCR preserved recent RNA Sequencing specimen TDRP tissues unique Usage viral DNA viral evolution viral genome viral genomes virus [DOI] 10.3390/v14061336 PMC 바로가기 [Article Type] Review
Favorable vaccine-induced SARS-CoV-2-specific T cell response profile in patients undergoing immune-modifying therapies면역 조절 요법을 받는 환자에서 유리한 백신 유도 SARS-CoV-2 특이적 T 세포 반응 프로파일Article Published on 2022-06-152022-09-12 Journal: The Journal of Clinical Investigation [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] B.1.1.529 biologic bowel catalyst Cellular immune response characterized COVID-19 COVID-19 vaccination cytokine demonstrated disease healthy individuals humoral IBD immune immunology Immunotherapy Infectious disease Inflammatory bowel disease inhibitor inhibitors lack magnitude methotrexate mRNA Mutation omicron Patient preserved reduced response SARS-CoV-2 spike-specific T cell sustained T cell T cell response therapy TNF treated treated patient Treatment vaccination [DOI] 10.1172/JCI159500 PMC 바로가기 [Article Type] Article
Antibody Response Induced by BNT162b2 and mRNA-1273 Vaccines against the SARS-CoV-2 in a Cohort of Healthcare Workers의료 종사자 집단에서 SARS-CoV-2에 대한 BNT162b2 및 mRNA-1273 백신에 의해 유도된 항체 반응Article Published on 2022-06-072022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] age analyzed anti-S antibodies antibody Antibody Response Arterial hypertension BMI BNT162b2 body mass body mass index clinical clinical variables Cohort confounders confounding factors Elecsy Elecsys healthcare Healthcare workers humoral immunogenicity hypertension individual induced infected with SARS-CoV-2 Infection levels of antibody lowest medians mRNA mRNA vaccine mRNA vaccines mRNA-1273 mRNA-1273 vaccine N protein non-infected nucleocapsid preserved Protein response Roche Diagnostics S protein SARS-CoV-2 SARS-COV-2 infection serology serum sample serum samples smoking subject subjects Switzerland the antibody response the S protein the SARS-CoV-2 U/mL uninfected vaccination Vaccine variable worker [DOI] 10.3390/v14061235 PMC 바로가기 [Article Type] Article
Integration of omics data to generate and analyse COVID-19 specific genome-scale metabolic modelsomics 데이터를 통합하여 COVID-19 특정 게놈 규모 대사 모델 생성 및 분석Article Published on 2022-06-012022-09-11 Journal: Computers in biology and medicine [Category] 바이오마커, 유전자 메커니즘, 치료제, [키워드] addressed analyses Analysis Antiviral applied approach cholesterol cholesterol metabolism code Combination complex Context-specific models COVID-19 COVID-19 patients dataset datasets disease down-regulated downregulated downregulation enrichment FIVE generate genome-scale metabolic models host response include indicated Infection integration MEM metabolic Metabolic enrichment analysis metabolic pathway metabolic pathways metabolism Model Model extraction methods. observation observations predicted prediction preserved Previous studies previous study produced provided retinol separated targets transcriptomic Variability Vitamin D3 [DOI] 10.1016/j.compbiomed.2022.105428 PMC 바로가기 [Article Type] Article
Immunoglobulin G immune response to SARS-CoV-2 vaccination in people living with multiple sclerosis within Multiple Sclerosis Partners Advancing Technology and Health Solutions다발성 경화증 파트너 내에서 다발성 경화증 환자의 SARS-CoV-2 예방 접종에 대한 면역 글로불린 G 면역 반응 기술 및 건강 솔루션 발전Article Published on 2022-06-012022-09-12 Journal: Multiple sclerosis (Houndmills, Basingstoke, Engla [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Advancing anti-CD20 blood sample Disease-modifying therapy humoral humoral immune response IgG IgG response immune immune response Immunoglobulin Immunoglobulin G management mRNA vaccine MS PATHS Multiple multiple sclerosis optimal management. partner preserved reactive receptor reduce SARS-CoV-2 SARS-CoV-2 vaccination sclerosis solution sphingosine technology tested therapy vaccination [DOI] 10.1177/13524585211061343 PMC 바로가기 [Article Type] Article
Concordance in RT-PCR detection of SARS-CoV-2 between samples preserved in viral and bacterial transport medium바이러스 및 박테리아 수송 배지에 보존된 샘플 간의 SARS-CoV-2 RT-PCR 검출 일치Article Published on 2022-06-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] All participants analyzed Bacteria Bacterial calculated collected Community Concordance Ct values cycle threshold determine Diagnostic method Glucose Glycerin in viral independent independent of longitudinal cohort study medium nasal nasal swab nasal swabs nasopharyngeal Nasopharyngeal swab NP swab NP swabs ORF1 ORF1ab participant Pathogens preserved real time respiratory pathogen respiratory symptoms RT-PCR RT-PCR detection Sample SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 infections skim milk specimen statistically Swab swabs targets Transport Transport media transport medium tryptone Viral transport medium VTM was used while [DOI] 10.1016/j.jviromet.2022.114522 PMC 바로가기 [Article Type] Article
Breakthrough SARS-CoV-2 infections after COVID-19 mRNA vaccination in MS patients on disease modifying therapies during the Delta and the Omicron waves in ItalyResearch article Published on 2022-05-052022-10-05 Journal: EBioMedicine [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] antibody Blood breakthrough infections calculated COVID-19 COVID-19 mRNA Vaccination cumulative Delta Delta wave disease Disease modifying treatments dose enrolled finding Follow-up funding humoral immune response identify incidence Infection Italian Italy MONITOR mRNA vaccination multicenter cohort study Multiple multiple sclerosis omicron Patient preserved Probability protective role reduced reduction risk risk of infection SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection sclerosis second dose significantly therapy Vaccine vaccine dose vaccine doses [DOI] 10.1016/j.ebiom.2022.104042 [Article Type] Research article