COVID-19 Modulates Inflammatory and Renal Markers That May Predict Hospital Outcomes among African American MalesCovid-19는 아프리카 계 미국인 남성의 병원 결과를 예측할 수있는 염증 및 신장 마커를 조절합니다.Article Published on 2021-12-022022-08-31 Journal: Viruses [Category] SARS, 바이오마커, [키워드] addition Admission African American African Americans age Care CCL2 CCL3 clinical factors collected control group controls COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines death demographics eight electronic medical records elevated evaluated Evidence Factor GST Hospital mortality Hospitalization Hospitalized ICU ICU patient ICU Patients IL-18 IL-33 IL-6 immune response immune responses In-hospital in-hospital mortality Infection Inflammatory response initial Injury interleukin male males marker MCP-1 MCP-1/CCL2 medical history medical records MIP-1α MIP-1α/CCL3 non-ICU non-ICU patients osteopontin outcome patients patients hospitalized plasma samples Population populations Prognostic factor Prognostic factors renal renal toxicity reported Retrospective study risk SARS-CoV-2 selected Seven single-center suffered Toxicity upregulated variables [DOI] 10.3390/v13122415 PMC 바로가기 [Article Type] Article
Interactions of adenoviruses with platelets and coagulation and the vaccine-induced immune thrombotic thrombocytopenia syndrome혈소판 및 응고와 아데노바이러스의 상호작용 및 백신 유발 면역 혈전성 혈소판 감소증 증후군Review Published on 2021-12-012022-09-11 Journal: Haematologica [Category] SARS, 치료기술, [키워드] adenoviral vector adenoviral vectors Adenovirus adenovirus-based affected age antibody AstraZeneca benefit Blood coagulation Characteristics Clinical data Coagulation Course COVID-19 pandemic Disseminated intravascular coagulation Economy Endothelium epidemiological studies Evidence Evolution fertile global health Health hypothese identify immune immunological reaction Infection Interaction intravascular coagulation janssen mechanism patients Platelet Platelets Prognostic factor Prognostic factors proportion reported Research subject syndrome thrombocytopenia thrombotic thrombotic complication thrombotic event triggering unique vaccination Vaccine Vaccines venous vessels women [DOI] 10.3324/haematol.2021.279289 PMC 바로가기 [Article Type] Review
Factors Associated with 90-Day Mortality in Invasively Ventilated Patients with COVID-19 in Marseille, FranceArticle Published on 2021-11-302022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress syndrome age Analysis ARDS carried Clinical characteristics Cohort Comorbidity conducted COVID-19 determine elevated eligible Factor for inclusion France ICU ICU admission ICUs intensive care unit Invasive mechanical ventilation invasively ventilated patient invasively ventilated patients laboratory-confirmed management Marseille mechanical ventilation mechanically ventilated patients median Mortality multivariable analysis number of comorbidity Occurrence Patient patients with COVID-19 predictor Primary outcome Prognostic factors Respiratory failure Retrospective study risk factor Risk factors SARS-CoV-2 severity statistical analysis thrombosis university hospital Ventilation with COVID-19 [DOI] 10.3390/jcm10235650 PMC 바로가기 [Article Type] Article
Clinical Relevance of Elevated Soluble ST2, HSP27 and 20S Proteasome at Hospital Admission in Patients with COVID-19Article Published on 2021-11-152022-10-28 Journal: Biology [Category] COVID-19, [키워드] “COVID-19 “cytokine storm” 20S proteasome acute respiratory syndrome addition analyzed ARDS association AUC Biomarker blood draw cause clinical clinical picture collected Coronavirus-2 Course COVID-19 COVID-19 disease COVID-19 patients COVID-2019 Critical critical appraisal demonstrated described disease disintegration Disseminated intravascular coagulation elevated endpoints evidenced Heat shock help high-risk patient higher risk hospital Hospital admission HSP27 Human hyperinflammation identify immune immune system immunological in-hospital mortality independent indicated Infection Inflammatory Inflammatory cytokine Interpretation invasive ventilation investigated mechanism Mortality notable outbreak oxygen support pandemic pathophysiology Patient patients with COVID-19 plasma Prognostic factor Prognostic factors proteasome Protein Relevance remained Research risk SARS-CoV-2 Sepsis septic patient serological data serum serum sample simple sST2 ST2 subsequent therapeutic interventions undergo Ventilation with COVID-19 [DOI] 10.3390/biology10111186 PMC 바로가기 [Article Type] Article
Link between serum lipid signature and prognostic factors in COVID-19 patientsCOVID-19 환자의 혈청 지질 특징과 예후 인자 사이의 연관성Article Published on 2021-11-042022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 임상, 치료기술, [키워드] (C-reactive protein) Affect affected age Analysis analyzed Biomarker C-reactive protein ceramide Coagulation COVID-19 COVID-19 patient COVID-19 patients creatinine Critical D-dimer Defense Disease progression disease progression and severity dyslipidemia Effect exhibited FIVE Horowitz hypoxia identify impairment index Inflammation Kidney function Lipid Lipidomics lipids MONITOR outcome outcomes oxidative stress Patient Prognostic factor Prognostic factors Prognostic markers reduced respiratory respiratory tract sera serum serum lipid Serum lipids severity sphingomyelin sphingomyelins sulfatide the disease the patient translation Viral viral infection [DOI] 10.1038/s41598-021-00755-z PMC 바로가기 [Article Type] Article
Association between prognostic factors and the outcomes of patients infected with SARS-CoV-2 harboring multiple spike protein mutations다중 스파이크 단백질 돌연변이가 있는 SARS-CoV-2에 감염된 환자의 예후 인자와 결과 사이의 연관성Article Published on 2021-11-012022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 유전자 메커니즘, 진단, [키워드] 95% CI age Anticoagulant anticoagulant therapy association clade Comorbidities conducted correlated COVID-19 COVID-19 patient COVID-19 patients Critical D614G mutation determined by diabetes disease Factor Factors followed by genomic Genomic surveillance Hospitalization hospitalized patient hospitalized patients host genetics hypertension Illumina Miseq infected with SARS-CoV-2 investigated Mild symptom mild symptoms moderate Molecular medicine Mortality Most patient Most patients Multivariate analysis Mutation mutations no symptom no symptoms outcome outcomes Patient patients with COVID-19 patients’ mortality Prognostic factor Prognostic factors reached recruited Risk factors S protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants Sequencing significant difference significantly Spike protein steroid Surveillance Viral whole-genome sequencing [DOI] 10.1038/s41598-021-00459-4 PMC 바로가기 [Article Type] Article
Heart-rate-variability (HRV), predicts outcomes in COVID-19심박수 변동성(HRV), COVID-19의 결과 예측Research Article Published on 2021-10-282022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Admission adverse outcome adverse outcomes Asymptomatic disease bpm bradycardia Cardiac arrhythmia cardiac arrhythmias clinical manifestations consecutive patient COVID-19 COVID-19 infection death determine diagnosed ECG examined greater heart rate Hospitalization Hospitalized HRV ICU immune response independent independent of Inflammation intensive care intensive care unit interval marker median value Mild Mortality Older outcome pacemaker Patient patients hospitalized predict predicted Premature Premature contractions Previous studies previous study Prognostic factors Prognostic value protective role recorded Result retrospective cohort study risk Standard deviation survival Tachycardia vagus nerve variety ventricular with COVID-19 younger patients [DOI] 10.1371/journal.pone.0258841 PMC 바로가기 [Article Type] Research Article
Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach정량적 단백질 학적 접근법을 사용하여 심한 코비드 -19의 혈청 예후 바이오 마커의 확인Article Published on 2021-10-192022-08-31 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, 진단, 치료법, [키워드] acquisition approach best Biomarkers Cardiovascular disorders characterized CHI3L1 Clinical prognosis COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 prognosis cytokine cytokine signaling determine diagnostic differential expression differentially expressed ELISA assay evaluated Health help identification identify IGFALS IL-6 implicated Ingenuity Pathway Analysis interleukin introduced mass spectrometry Necrosis Patient predicted predictor Prognosis prognostic biomarker Prognostic factor Prognostic factors Prognostic markers progression Protein proteomic Proteomic analysis Quantitative regulated serum Serum protein serum proteins severe COVID-19 severe COVID-19 patients severe disease severely ill COVID-19 patients systemic inflammatory response the disease TNF Treatment Tumor tumor necrosis tumor necrosis factor viral infection with COVID-19 [DOI] 10.1038/s41598-021-98253-9 PMC 바로가기 [Article Type] Article
Body composition predictors of outcome in patients with COVID-19COVID-19 환자의 결과에 대한 체성분 예측 인자Article Published on 2021-10-012022-09-11 Journal: International journal of obesity (2005) [Category] 바이오마커, [키워드] 95% CI abdominal muscle adipose Adipose tissue adjusted Admission adverse outcome adverse outcomes age Biomarker BMI Body body composition cardiometabolic clinical clinical information Comorbidities competing cross-sectional area CsA death Deceased distribution elevated fat hazard ratio Hospital admission ICU ICU admission increase in independent independent of information intensive care intensive care unit measure median median age median time multivariate muscle mass obesity outcome Patient patients hospitalized patients with COVID-19 predictor Prognostic factors reduced Retrospective study risk risk factor SAT Sex single hospital Standard deviation study group time of death tissue visceral were assessed with COVID-19 [DOI] 10.1038/s41366-021-00907-1 PMC 바로가기 [Article Type] Article
Lower blood pH as a strong prognostic factor for fatal outcomes in critically ill COVID-19 patients at an intensive care unit: A multivariable analysisResearch Article Published on 2021-09-292022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] 19 patients died Analysis analyzed Blood pH center Cohort Course COVID-19 patient Critically ill evaluated expected Germany IMPROVE in-hospital mortality intensive care intensive care unit Lactate Lower mean arterial pressure Mortality multivariable analysis multivariable logistic regression multivariable regression models no significant difference outcome oxygen parameter patients treated pH value procalcitonin Prognostic factor Prognostic factors Regensburg Result retrospective cohort study the disease the mean treatment strategy university [DOI] 10.1371/journal.pone.0258018 PMC 바로가기 [Article Type] Research Article