18 F-FDG PET-CT incidental lung findings in asymptomatic COVID-19 patients: evidences from the Italian core of the first pandemic peakOriginal Article Published on 2022-01-012022-10-27 Journal: Asia Oceania Journal of Nuclear Medicine and Biology [Category] COVID-19, [키워드] alteration Asymptomatic Asymptomatic COVID-19 Combination consolidation consolidations COVID-19 COVID-19 outbreak early stage evaluated Evidence extension FDG FDG uptake Follow-up GGO increase in interstitial interstitial pneumonia involved Italian lobe lobes lung lung involvement lung lesion Molecular tests nonspecific pandemic parameter Patient performed pet PET-CT pulmonary involvement ranged SARS-CoV-2 SUV [DOI] 10.22038/AOJNMB.2021.58035.1405 PMC 바로가기 [Article Type] Original Article
Efficacy of a Low Dose of Melatonin as an Adjunctive Therapy in Hospitalized Patients with COVID-19: A Randomized, Double-blind Clinical TrialRandomized Controlled Trial Published on 2022-01-012022-10-05 Journal: Archives of medical research [Category] SARS, 임상, [키워드] 1:1 Adjunctive therapy adjuvant adverse event anti-inflammatory agent assigned baseline Characteristics clinical Clinical efficacy Clinical outcome clinical symptom clinical trial contribute control group coronavirus disease cough COVID-19 COVID-19 patient CRP death dose double-blind Dyspnea evaluate faster fatigue Health hospital discharge hospitalized patient immune IMPROVE in both groups intervention group Iran Laboratory melatonin Mild Moderate COVID-19 pathophysiology Patient patients with COVID-19 post-intervention pulmonary involvement radiological finding randomized clinical trial Randomly receive Safety significantly significantly shorter single-center Standard of care study group Tehran Treatment were assessed [DOI] 10.1016/j.arcmed.2021.06.006 PMC 바로가기 [Article Type] Randomized Controlled Trial
Giant compressive emphysema: a rare complication of COVID-19Case Report Published on 2021-12-302022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Antibiotic therapy association beta-coronavirus chronic obstructive Comorbidities complication of COVID-19 coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Critical CT scan curative described Diagnosis dose emphysema evaluate Giant had no Hospitalization Hospitalized ipsilateral lung lung involvement Manifestations oxygen Oxygen therapy Pain Patient Physical examination Pneumonia Prognosis pulmonary disease pulmonary involvement pulmonary parenchyma responsible RNA SARS-CoV-2 severity Structure subject the patient Thoracic Thoracic CT scan tympany was performed worldwide pandemic [DOI] 10.1186/s12879-021-07006-6 PMC 바로가기 [Article Type] Case Report
High CD169 Monocyte/Lymphocyte Ratio Reflects Immunophenotype Disruption and Oxygen Need in COVID-19 PatientsArticle Published on 2021-12-182022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] analyzed B-cell Biomarker Blood blood cell blood sample CD169 CD8 T-cell clinical outcomes correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 therapy cytokine Cytokine storm disease Disease progression Disruption dose-dependent manner Evidence flow cytometry fluorescence intensity healthy donor Hospitalization IL-10 IL-6 immune dysfunction immunophenotype in vitro Inflammation inflammatory markers lymphocyte marker maturation monocyte mRNA expression mRNA levels outcome overexpressed Patient PBMC Pneumonia Predictive pulmonary involvement Ratio Respiratory outcome SARS-CoV-2 severity sialoadhesin stimulated T-cell exhaustion the median the spike protein Transcription [DOI] 10.3390/pathogens10121639 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Antibodies in Hemodialysis Patients Six Months after Infection Compared to Healthcare WorkersResearch Article Published on 2021-12-012022-10-29 Journal: International Journal of Nephrology [Category] COVID-19, [키워드] antibody association BNP chest scan circulating circulating antibodies Cluster Clustering control group correlation COVID-19 CRP diagnosed dialysis First wave had more healthcare worker Hemodialysis humoral investigated Kidney disease lowest Lymphocyte count Month Oxygen requirements parameter Patient performed positive pulmonary involvement radiological Result Retrospective study SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection severe disease severity of COVID-19 the epidemic the patient the SARS-CoV-2 worker [DOI] 10.1155/2021/4747221 PMC 바로가기 [Article Type] Research Article
Methotrexate as a safe immunosuppressive agent during the COVID-19 pandemicObservational Study Published on 2021-12-012022-10-05 Journal: International immunopharmacology [Category] SARS, 임상, [키워드] appear contrary control group correlation cough COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 severity CRP level demonstrated disease Dyspnea ferritin Fever higher risk IL6 immune function immune system Immunocompromised Immunocompromised patient immunosuppressive agent Immunosuppressive medication inflammatory reaction inhibited less methotrexate Participants Patient pulmonary involvement reduced Safe severe COVID-19 Severe infection severity severity of COVID-19 significantly Symptoms T regulatory cells their family member therapy TNFα Treatment two groups White blood cell [DOI] 10.1016/j.intimp.2021.108324 PMC 바로가기 [Article Type] Observational Study
Pediatric anti-NMDA receptor encephalitis associated with COVID-19COVID-19와 관련된 소아 항NMDA 수용체 뇌염Case Reports Published on 2021-12-012022-09-12 Journal: Child's nervous system : ChNS : official journal o [Category] MERS, SARS, 진단, [키워드] abnormal movements absence acute ataxia acute respiratory syndrome Anti-N-methyl-D-aspartate receptor anti-NMDA receptor encephalitis antibody applied association Ataxia Autoimmune Autoimmune encephalitis autonomic changes characterized clinical condition clinical response conscious contraindications coronavirus coronavirus disease COVID-19 diagnosed discharged Encephalitis Encephalopathy Fever Intravenous immunoglobulin Lymphocyte count lymphopenia Neurological symptom NMDAR Patient pediatric pulmonary involvement pulse receptor SARS-CoV-2 SARS-COV-2 infection Seizures steroid steroid treatment the patient Treatment with COVID-19 [DOI] 10.1007/s00381-021-05155-2 PMC 바로가기 [Article Type] Case Reports
Response of patients with acute respiratory failure caused by COVID-19 to awake-prone position outside the intensive care unit based on pulmonary involvementObservational Study Published on 2021-11-252022-10-04 Journal: Clinics [Category] MERS, SARS, 임상, [키워드] 95% confidence interval age analyzed body mass index caused characteristic clinical Clinical outcome Comorbidities conducted COVID-19 COVID-19 patient Critical Care Outcome Cutoff cutoff point effective Endotracheal intubation evaluate hazard ratio hospital hypoxic respiratory failure ICU identify IMPROVE intensive care Intervention laboratory data lung median Mortality non-responder noninvasive respiratory Noninvasive ventilation outcome Oxygenation PaO parenchymal damage Patient patients with COVID-19 positive prevent disease progression Prone position prospective observational cohort pulmonary impairment pulmonary involvement reduce mortality Respiratory failure respiratory insufficiency Responder responders response sensitivity Sensitivity and specificity Sex specificity Support the patient Treatment treatments for COVID-19 ventilatory assistance [DOI] 10.6061/clinics/2021/e3368 PMC 바로가기 [Article Type] Observational Study
Predictors of the chest CT score in COVID-19 patients: a cross-sectional studyCOVID-19 환자의 흉부 CT 점수 예측 자 : 단면 연구Review Published on 2021-11-182022-09-01 Journal: Virology Journal [Category] MERS, SARS, 진단, [키워드] addition Anosmia blood cell C-reactive protein C-reactive protein (CRP Chain Reaction Chest CT chest CT scan Chest CT scans Chest CT score Clinical features Computed tomography consolidation COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 patients cross-sectional CT findings Dyspnea enrolled evaluated Fever first visit GGO glass Ground glass opacity hospital Hospitalization ICU ICU admission initial initial assessment Laboratory laboratory data laboratory findings Laboratory tests lesion lung involvement lung lesions Mortality myalgia opacity outcome outcomes participant Patient patients polymerase chain reaction positive predict pulmonary involvement recovery Recovery time respiratory rate Result RT-PCR scoring system semi-quantitative severity Symptom Symptoms university hospital vital signs WBC were recorded White blood cell [DOI] 10.1186/s12985-021-01699-6 PMC 바로가기 [Article Type] Review
Quantification of pulmonary involvement in COVID-19 pneumonia by means of a cascade of two U-nets: training and assessment on multiple datasets using different annotation criteriaOriginal Article Published on 2021-10-262022-10-29 Journal: International Journal of Computer Assisted Radiolo [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Accuracy affected analysed Analysis annotations automated bounding box cascade Chest computed tomography COVID-19 criteria dataset datasets Dice Effect evaluate evaluated Factor Ground-glass opacities identify independent investigated lesions lung machine learning Mask Measures Pneumonia predicted pulmonary involvement pulmonary lesions quantification quantified released Result score Segmentation supplementary material Tolerance U-NET volumetric were measured were used [DOI] 10.1007/s11548-021-02501-2 PMC 바로가기 [Article Type] Original Article