Is the COVID-19 pandemic impacting on the risk of African Swine Fever virus (ASFV) introduction into the United States? A short-term assessment of the risk factorsCOVID-19 대유행이 아프리카돼지열병 바이러스(ASFV)가 미국으로 유입될 위험에 영향을 미치고 있습니까? 위험 요인에 대한 단기 평가Article Published on 2022-07-012022-09-11 Journal: Transboundary and emerging diseases [Category] 치료기술, [키워드] 95%CI activities activity affected African African Swine Fever Virus Analysis China connection Consequences contagious contagious disease country COVID-19 COVID-19 pandemic disease driver Fever Flow global connections global public health Health crisis high mortality highlight highlighting identify International majority outbreak P-value pathway Pathways populations Prevent public health recognizing response Result risk risk factor Spread spread to the United State transboundary disease. United States virus was used zoonosis [DOI] 10.1111/tbed.14330 PMC 바로가기 [Article Type] Article
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 20212020년 4월부터 2021년 3월까지 헌혈자 보유 표본에서 일반적으로 사용되는 캐나다 SARS-CoV-2 효소 면역분석에 대한 Abbott SARS-CoV-2 IgG II 정량 분석의 정성적 비교Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료법, [키워드] 95% CI 95% confidence interval Abbott Abbott SARS-CoV-2 IgG aggregate Analysis analyzed anti-S anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Anti-spike antibody approach assays Blood donors can be used Canada Characteristics characterized Chicago collected detect ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays full-length spike glycoprotein glycoprotein gold gold standard house identify IgG IgG response IgG responses Laboratory methods comparisons nucleocapsid positive provide Qualitative qualitative test RBD Receptor binding Receptor binding domain recognizing reference standard Research retention SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antigens SARS-CoV-2 variant scored sensitivity serology Seropositivity specificity specimen spike spike glycoprotein standard error the SARS-CoV-2 the strongest threshold viral antigens wild-type [DOI] 10.1128/spectrum.01134-22 PMC 바로가기 [Article Type] Article
Anti-MDA5 Antibody Linking COVID-19, Type I Interferon, and Autoimmunity: A Case Report and Systematic Literature ReviewCOVID-19, I형 인터페론 및 자가면역을 연결하는 항MDA5 항체: 증례 보고 및 체계적인 문헌 검토Case Reports Published on 2022-06-272022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Activation anti-MDA5 syndrome antibody antiviral role Autoimmune Autoimmune disease Autoimmune diseases Cardiomyopathy Clinical features constitutional symptoms contribute correlated COVID-19 COVID-19 severity Cytokines differentiation antigen disease Disease activity elevated example explain Features IFN immune immune response immunological immunology in some induce Inflammatory inflammatory myositis interferons literature lung involvement Manifestations MDA5 mechanisms Melanoma myositis Patient Pattern recognition pattern recognition receptor protective effect Protective effects recognizing report review SARS-CoV-2 infected patients SARS-COV-2 infection searched severity signature similarities similarity skin manifestations Symptoms syndrome synthesis Trigger Type Type I IFN type I interferon type I interferon signature. type I interferons Viral viral infections virus viruses while with COVID-19 [DOI] 10.3389/fimmu.2022.937667 PMC 바로가기 [Article Type] Case Reports
Proteomic Analysis of Human Milk Reveals Nutritional and Immune Benefits in the Colostrum from Mothers with COVID-19모유의 단백질체 분석은 COVID-19에 걸린 산모의 초유에서 영양 및 면역 이점을 나타냅니다Article Published on 2022-06-172022-09-11 Journal: Nutrients [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] adaptive Analysis Antiviral antiviral properties antiviral property benefit Breastfeeding breastmilk casein collected colostrum control group COVID-19 COVID-19 patient COVID-19 patients debate epitope Epitopes Evidence evidence of exhibited glycosylation Health Organization healthy donors Human immune immune-related protein immune-related proteins Immunoglobulin Infant Infection lack mass spectrometry mature milk milk molecular basis mother protective effect Protein proteomics recognizing recommendation risk SARS-CoV-2 significantly higher significantly lower Structure total protein unique upregulated viral entry virus virus transmission whey protein. while with COVID-19 World Health Organization [DOI] 10.3390/nu14122513 PMC 바로가기 [Article Type] Article
Cross-Reactivity of IgG Antibodies and Virus Neutralization in mRNA-Vaccinated People Against Wild-Type SARS-CoV-2 and the Five Most Common SARS-CoV-2 Variants of Concern야생형 SARS-CoV-2 및 가장 흔한 5가지 우려되는 SARS-CoV-2 변이체에 대한 mRNA 예방접종을 받은 사람들의 IgG 항체 교차 반응성 및 바이러스 중화Article Published on 2022-06-152022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE-2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Against Alpha angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 angiotensin-converting enzyme-2 (ACE-2) approval Beta binding BNT162b2 common concern coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 domain Efficacy ELISA enzyme expressed FIVE house human cells IgG IgG titer IgG titers immune response in-house ELISA induce Infectious disease inhibit inhibited Inhibition assays initiated interaction site less MOST mRNA mRNA vaccine mRNA vaccines mRNA-1273 much lower neutralization neutralizing effect omicron Protein provided RBD RBDs receptor Receptor-binding domain Receptor-binding domain (RBD) recognizing respiratory S-protein SARS-CoV-2 SARS-CoV-2 spike severe acute respiratory syndrome Coronavirus the RBD the SARS-CoV-2 vaccination Vaccine variants variants of concern virus VOCs wild-type wild-type SARS-CoV-2 [DOI] 10.3389/fimmu.2022.915034 PMC 바로가기 [Article Type] Article
Identification and application of a pair of noncompeting monoclonal antibodies broadly binding to the nucleocapsid proteins of SARS-CoV-2 variants including OmicronOmicron을 포함한 SARS-CoV-2 변이체의 뉴클레오캡시드 단백질에 광범위하게 결합하는 비경쟁 단일클론항체 쌍의 확인 및 적용Article Published on 2022-05-282022-09-11 Journal: Virology Journal [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] Alpha Analysis Antigen Beta binding biochemical assay Clinical diagnosis Delta enzyme Epitopes evaluated flow cytometry focus highlighting identification immunofluorescence immunosorbent linear epitope Live virus mAb mAbs monoclonal antibody neutralization neutralization test nucleocapsid protein omicron pair Protein recognizing reduction reported SARS-CoV SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 variant SARS-CoV-2 variants virus infection viruses western blot [DOI] 10.1186/s12985-022-01827-w PMC 바로가기 [Article Type] Article
A Novel Human Neutralizing mAb Recognizes Delta, Gamma and Omicron Variants of SARS-CoV-2 and Can Be Used in Combination with Sotrovimab새로운 인간 중화 mAb는 SARS-CoV-2의 델타, 감마 및 오미크론 변이체를 인식하고 소트로비맙과 함께 사용할 수 있습니다Article Published on 2022-05-162022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] ACE-2 ACE-2 receptor angiotensin angiotensin converting enzyme anti-spike MAbs antibody Can Casirivimab caused Cell culture cell cultures cell entry Clinical use combinatorial treatment combinatorial treatments coronavirus Delta diagnostic drug ENhance epidemics/pandemics epitope Epitopes Gamma glycoprotein Human Imdevimab immune system Infection inhibitory effect Interaction interfere investigated mAb mAbs monoclonal monoclonal antibodies Neutralizing Neutralizing activity neutralizing mAbs. novel omicron Omicron variant pandemic Pandemics Patient RBD Receptor binding domain recognize recognizing SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 virus Scientific community Sotrovimab spike spike glycoprotein Spike-RBD/ACE-2 subsequent the antibody the Spike therapeutic therapy variants virus virus infection [DOI] 10.3390/ijms23105556 PMC 바로가기 [Article Type] Article
IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial functionClinical Medicine Published on 2022-05-092022-10-04 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] 95% CI ACE2 activate activated Activation acute respiratory distress analyzed angiotensin-converting enzyme 2 autoantibody Autoimmunity Award Biomarker Blood career changes in class-switching clinical feature Clinical outcome complement contribute coronavirus SARS-CoV-2 COVID-19 demonstrated development disease division Donald Effect ELISA Endothelial cell endothelial function expressed foundation functional Gate heart Host immune response identify IgG IgM Implications independent initiated Inpatients Intramural Jerome Melinda Gate NIH Non-COVID-19 pathology Patient patients with moderate receptor recognizing Result rheumatology SARS-COV-2 infection Science severe COVID-19 severe disease syndrome T cell the SARS-CoV-2 therapeutic undergo Vascular Vascular endothelium ventilated patient vessel [DOI] 10.1172/jci.insight.158362 PMC 바로가기 [Article Type] Clinical Medicine
The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies숙주와 SARS-CoV-2의 전투: 선천 면역과 바이러스 회피 전략Review Published on 2022-05-042022-09-11 Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] activated Antiviral antiviral gene antiviral genes antiviral targets caused confirmed cases COVID-19 death Defense evade highlight Host host response immune immune evasion immune surveillance Immunity Inflammation Innate innate immune innate immune response innate immune system Innate immunity interferon interferons Invasion knowledge life cycle mechanism pathogen Pattern recognition pattern recognition receptor Pattern recognition receptors PRRs recognizing Replication restrict resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus Signaling signaling cascade signaling transduction. Surveillance transduction type I type I and III interferons viral life cycle viral spread [DOI] 10.1016/j.ymthe.2022.02.014 PMC 바로가기 [Article Type] Review
Diagnostic Accuracy of Chest Digital Tomosynthesis in Patients Recovering after COVID-19 PneumoniaCOVID-19 폐렴 후 회복 중인 환자의 흉부 디지털 단층 합성의 진단 정확도Observational Study Published on 2022-04-242022-09-11 Journal: Tomography [Category] SARS, 임상, 치료기술, [키워드] Accuracy Admission age air bronchogram analyzed approval ARDS average Average dose Berlin criteria bronchogram calculated carried changes in Chest chest digital tomosynthesis chest imaging chest X-ray Complete Computed tomography consolidation COVID-19 COVID-19 pneumonia criteria CT scan CXR Diagnosis diagnostic Diagnostic accuracy dose DTS emergency department Follow-up followed by GGO GGOs Ground-glass opacities ground-glass opacity hospital inclusion criteria Indicator interstitial linear Local lung Lung disease material Nasopharyngeal swab nasopharyngeal swabs observational study Patient patients performed Pneumonia positive RT-PCR R statistical software radiologist recognizing retrospective SARS-COV-2 infection severe COVID-19 significantly higher Standard deviation Version [DOI] 10.3390/tomography8030100 PMC 바로가기 [Article Type] Observational Study