Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene세포 miR-150-5p는 NSP10 유전자를 조절함으로써 SARS-COV-2 감염의 생물학에서 중요한 역할을 할 수있다.Research Article Published on 2021-12-142022-09-10 Journal: RNA Biology [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] analysed Analysis biology of SARS-CoV-2 Biomarker Biomarkers Cell Chain Reaction change circulating circulating biomarkers circulating miRNA circulating miRNAs co-transfection coding strand Combination conducted COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients disease Effect experiment expression followed by healthy controls in vitro Infection infection assays inhibit SARS-CoV-2 inhibited inhibitor mechanism miR-150 miR-150-5p miR-375 miRNA miRNA profile miRNAs moderate-severe modulating NGS nsp10 performed plasma Plasma levels polymerase chain polymerase chain reaction promote provide real-time polymerase chain reaction remains uncertain reversed RT-qPCR SARS-CoV-2 SARS-COV-2 infection Sequencing significant changes in significantly Support T cells transfection western blotting [DOI] 10.1080/15476286.2021.2010959 PMC 바로가기 [Article Type] Research Article
Seroepidemiological Survey on the Impact of Smoking on SARS-CoV-2 Infection and COVID-19 Outcomes: Protocol for the Troina StudyProtocol Published on 2021-11-222022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] added antibody antibody persistence association biochemically Blood blood sample Care changes in clinical feature collected cotinine COVID-19 demographics disease severity estimate follow-up time Health high risk Identifier Impact individual individuals Infection information metabolite methodology objective outcome outcomes pandemic Prevalence proportion prospective cohort study public health public health measure recruitment remains uncertain report Research Result risk factor SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2–specific antibody screened Seroprevalence serum smoking smoking impact smoking status Spread survey susceptibility [DOI] 10.2196/32285 PMC 바로가기 [Article Type] Protocol
Prevalence and Risk Factors of SARS-CoV-2 Infection among Parturients and Newborns from Luanda, AngolaArticle Published on 2021-11-162022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] age Angola Antenatal carried China consequence COVID-19 COVID-19 case creating cross-sectional disease Factor Follow-up Infection intensive management investigated Luanda maternal breastfeeding mother Neonate Newborn newborn screening parturient Pharyngeal swab positive Pregnancy pregnant women previous study public health Rapid remains uncertain risk factor RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission Seven severity tested Testing Transmission [DOI] 10.3390/pathogens10111494 PMC 바로가기 [Article Type] Article
The in vitro and in vivo efficacy of CT-P59 against Gamma, Delta and its associated variants of SARS-CoV-2SARS-CoV-2의 감마, 델타 및 관련 변이체에 대한 CT-P59의 시험관내 및 생체내 효능Article Published on 2021-11-122022-09-11 Journal: Biochemical and Biophysical Research Communication [Category] MERS, SARS, 변종, 진단, 치료제, [키워드] abrogation antibody Antiviral effect Beta beta variants carried cause Cell cells CT-P59 Delta delta variant effective Efficacy Epsilon experiment experiments Gamma in vitro in vivo Infection infections L452R neutralization Patient question reduced regdanvimab remains uncertain reported respiratory respiratory tract SARS-CoV-2 SARS-CoV-2 variant susceptibility Symptom Therapeutic antibody. therapeutic potential variant variants variants of SARS-CoV-2 virus [DOI] 10.1016/j.bbrc.2021.09.023 PMC 바로가기 [Article Type] Article
Skin manifestations associated with COVID-19 ☆Review Published on 2021-11-102022-10-04 Journal: Anais Brasileiros de Dermatologia [Category] MERS, SARS, 변종, [키워드] androgen article case sery condition conducted Consensus contribute correlation COVID-19 Dermatology Diagnosis differential diagnose EPL European country exclusion frequencies Frequency histopathological increasingly information knowledge lesions manifestation mechanism organ pandemic pathophysiology Prognosis remains uncertain responsible severity skin skin manifestation specific treatment subject systematic reviews the disease USA with COVID-19 [DOI] 10.1016/j.abd.2021.08.002 PMC 바로가기 [Article Type] Review
Humoral responses to SARS-CoV-2 mRNA vaccines: Role of past infectionSARS-COV-2 mRNA 백신에 대한 체액 반응 : 과거 감염의 역할Research Article Published on 2021-11-082022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody titers biologic BNT162b2 BNT162b2 vaccine BNT162b2 vaccines booster completion decay demonstrated Department detect dose enrolled fire first responders Health Service Humoral response humoral responses immune responses immunoassay implication individual individuals infected individual Infection Los Angele Los Angeles magnitude median Microparticle mRNA mRNA vaccine mRNA-1273 mRNA-based vaccine mRNA-based vaccines naïve naïve individuals NPI pandemic protective immune response remains uncertain required respiratory Responder robust antibody response robust antibody responses role SARS-CoV-2 SARS-CoV-2 spike Severe acute respiratory syndrome spike subset two-dose regimen understanding University of California Vaccine vaccine dose vaccinee vaccinees was used [DOI] 10.1371/journal.pone.0259703 PMC 바로가기 [Article Type] Research Article
The effect of eye protection on SARS-CoV-2 transmission: a systematic reviewSARS-COV-2 전송에 대한 눈 보호 효과 : 체계적인 검토Research Published on 2021-11-042022-09-10 Journal: Antimicrobial Resistance and Infection Control [Category] MERS, SARS, 변종, [키워드] 95% CI adjusted article CENTRAL certainty certainty of evidence changes in clinical trial clinical trials Cochrane Library Community comparative observational study confounder country COVID-19 current determine Effectiveness Europe explained Eye protection Face shield glasses Goggles healthcare Healthcare workers heterogeneity India Infection prevention infection with SARS-CoV-2 Meta-analysis observational studies observational study Odds ratio Odds ratios PMC populations precluded Prevent Protective behaviours reduction Relative risk remains uncertain reported Research Result retrospective cohort study Risk of bias risk reduction robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections screened searched statistically significant subsequent substantial reduction substantial reductions supplementary material systematic review tested transmission of SARS-CoV-2 Trial United Kingdom USA variants [DOI] 10.1186/s13756-021-01025-3 PMC 바로가기 [Article Type] Research
Nationwide rollout reveals efficacy of epidemic control through digital contact tracingArticle Published on 2021-10-112022-10-04 Journal: Nature Communications [Category] MERS, SARS, 치료기술, [키워드] close contact collected Computational models Computer science Contact Contact tracing COVID-19 dataset Effectiveness Efficacy Epidemic Epidemiological study Epidemiology Evidence help indicated individual lack Measures moderate Norway Outbreaks over pandemic public health remains uncertain reveal SARS-CoV-2 spring unique was measured [DOI] 10.1038/s41467-021-26144-8 PMC 바로가기 [Article Type] Article
Comparison of 11 respiratory pathogens among hospitalized children before and during the COVID-19 epidemic in Shenzhen, China중국 심천의 Covid-19 전염병 전과 중에 입원 어린이들 사이에서 11 개의 호흡기 병원체의 비교Comparative Study Published on 2021-10-092022-09-10 Journal: Virology Journal [Category] MERS, SARS, 치료기술, [키워드] Acute respiratory infection acute respiratory infections Adenovirus analyzed children China circulation collected COVID-19 COVID-19 epidemic detection rate enrolled Epidemic Hospitalized Human human metapneumovirus human parainfluenza virus Human respiratory syncytial virus Human rhinovirus Influenza influenza A measure Multiplex PCR Mycoplasma pneumoniae nasopharyngeal swabs outbreak parainfluenza virus pathogen Pathogens Patient pneumoniae Prevalence preventive measure preventive measures remains uncertain respiratory respiratory pathogen Respiratory pathogens respiratory syncytial virus respiratory tract infection Result rhinovirus SARS-CoV-2 Seasonal influenza Shenzhen significantly lower Swab virus [DOI] 10.1186/s12985-021-01669-y PMC 바로가기 [Article Type] Comparative Study
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective단일 분자 관점에서 염기 유사체에 의한 SARS-CoV-2 중합효소 억제Research Article Published on 2021-10-072022-09-10 Journal: eLife [Category] SARS, 변종, 유전자 메커니즘, 치료제, [키워드] absence Antiviral antiviral drug antiviral drugs antiviral protein applied approach approved assays base block blocks can not catalytic cause Cell cells condition contrary coronavirus COVID-19 develop drug effective Efficiency eLife evade examined FDA food Genetic genetic information high throughput magnetic tweezers impair IMPROVE incorporation information inhibition interfere knowledge leads less location Magnetic field mechanism mechanism of action mode Modification molecule MOST nucleotide nucleotides occur outbreak Outbreaks pandemic Particles Perspective platform polymerase polymerases Precision PROTECT Protein protein complex question RDV recognize remains uncertain Remdesivir replicate Replication replication mechanism responsible ribose RNA synthesis SARS-CoV-2 SARS-CoV-2 pandemic sequence single molecule biophysics Spread synthesis termination the SARS-CoV-2 Therapeutics Treatment US Food and Drug Administration Vaccine development vaccine-resistant variant variant Viral Viral RNA viral RNA synthesis virus worsened [DOI] 10.7554/eLife.70968 PMC 바로가기 [Article Type] Research Article