Genetics of symptom remission in outpatients with COVID-19COVID-19 외래 환자의 증상 완화 유전자Randomized Controlled Trial Published on 2021-05-252022-09-01 Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 임상, 진단, [키워드] allele association clinical trial Colchicine ColCorona conducted contribute COVID-19 symptom COVID-19 symptoms disease severity Genome-wide association studies Genome-wide association study highlighting hospitalisations Interaction NPR3 Outpatient participant pathway peptide Placebo receptor Remission replicated risk risk factor Symptom treated viral infection with COVID-19 [DOI] 10.1038/s41598-021-90365-6 PMC 바로가기 [Article Type] Randomized Controlled Trial
Pathways Improving Compliance with Preventive Behaviors during the Remission Period of the COVID-19 PandemicArticle Published on 2021-03-282022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] accompanied age Anxiety associations Behavior China Chinese Compliance compliance with preventive behaviors COVID-19 COVID-19 outbreak COVID-19 pandemic dispositional optimism Factor fear Government government dependency implication Improving infection control initial mediation model moderate negative emotions optimism participant participated Period political trust provided public health authorities reduce Remission Research Risk perception Self-efficacy [DOI] 10.3390/ijerph18073512 PMC 바로가기 [Article Type] Article
Effect of age, comorbidity and remission status on outcome of COVID-19 in patients with hematological malignanciesObservational Study Published on 2021-03-012022-10-05 Journal: Blood cells, molecules & diseases [Category] 임상, [키워드] 28-day mortality age anticancer antivirals Chemotherapy Cohort cohorts Comorbidity conducted contributed cough COVID-19 COVID-19 in patient COVID-19 infection death rate disease Effect elderly enrolled Hematological malignancies Hematological malignancy hematology India Infection lymphoid malignancy mild infection moderate MOST multicentre negativity one patient outcome oxygen Patient Remission RT-PCR Secondary objective Seven Severe COVID-19 Infection severe disease Severe infection significantly study period survival Total Treatment [DOI] 10.1016/j.bcmd.2020.102525 PMC 바로가기 [Article Type] Observational Study
Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled TrialInfectious Disease Published on 2021-02-222022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accelerated acute respiratory syndrome affected AGA Androgen receptor androgenetic alopecia anti-androgen therapy average clinical coronavirus COVID-19 Day defined dependent on double-blinded drugs expressed female female subject inhibitor less men Mild moderate Moderate COVID-19 Modification Patient patients treated Placebo positive proxalutamide Randomized receptor recruited reduced regulated Remission reported Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test severe coronavirus disease significantly subject subjects the placebo group time TMPRSS2 transmembrane transmembrane protease serine 2 treated Treatment Type II pneumocyte viral clearance viral spike protein [DOI] 10.7759/cureus.13492 PMC 바로가기 [Article Type] Infectious Disease
Case Report: Severe Complement-Mediated Thrombotic Microangiopathy in IgG4-Related Disease Secondary to Anti-Factor H IgG4 AutoantibodiesImmunology Published on 2021-02-112022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] amplification Analysis analyzed anti-factor H auto-antibodies antibodies assays Atypical hemolytic uremic syndrome auto-antibody autoantibodies autoantibody Case report CFH complement Complement C3 Complement factor H complement factor H-related protein Corticosteroids Cyclophosphamide Deletion deletions diagnosed disease disorders ELISA ENhance Exome Human IgA IgG IgG4 IgG4-related disease Immunoglobulin implicated inhibitory isotype Meningitis microangiopathy multiplex objective pathogenic Patient performed predisposition presenting probe Remission Result retrospective SARS CoV2 SARS-CoV-2 pneumonia secondary antibody secondary to Sequencing susceptibility System the patient thrombotic thrombotic microangiopathy [DOI] 10.3389/fimmu.2020.604759 PMC 바로가기 [Article Type] Immunology
Comparison of the Efficacy and Safety of Tacrolimus and Low-Dose Corticosteroid with High-Dose Corticosteroid for Minimal Change Nephrotic Syndrome in AdultsClinical Research Published on 2021-01-092024-09-04 Journal: Journal of the American Society of Nephrology [Category] 대상포진, [키워드] Corticosteroid Glomerulonephritis Immunosuppression nephrotic syndrome Remission tacrolimus [DOI] 10.1681/ASN.2019050546 PMC 바로가기 [Article Type] Clinical Research
Early combination therapy with etanercept and methotrexate in JIA patients shortens the time to reach an inactive disease state and remission: results of a double-blind placebo-controlled trialResearch Article Published on 2021-01-062024-09-02 Journal: Pediatric Rheumatology Online Journal [Category] 대상포진, [키워드] juvenile idiopathic arthritis Remission TNF inhibitor [DOI] 10.1186/s12969-020-00488-9 PMC 바로가기 [Article Type] Research Article
Complement activation and endothelial perturbation parallel COVID-19 severity and activity보완 활성화 및 내피 교란은 COVID-19 심각도 및 활동과 병행합니다.Article Published on 2021-01-012022-08-31 Journal: Journal of autoimmunity [Category] MERS, SARS, 바이오마커, [키워드] Activation animal animal models association Biomarker Biomarkers C5a cohort study complement Complement activation complement system contribute coronavirus coronavirus disease coronavirus disease-2019 correlated COVID-19 COVID-19 patients COVID-19 severity disease severity endothelial endothelial damage endotheliopathy Endothelium evaluate evaluated high plasma level high plasma levels Hospital admission hypercoagulability manifestation Mild moderate pathophysiology Patient patients with COVID-19 plasma progression Remission SC5b-9 selectin severe disease severity significantly significantly increased target the disease the patient therapy tissue injury von Willebrand factor were measured [DOI] 10.1016/j.jaut.2020.102560 PMC 바로가기 [Article Type] Article
Inflammatory markers in gynecologic oncology patients hospitalized with COVID-19 infectionCOVID-19 감염으로 입원한 부인과 종양 환자의 염증 표지자Multicenter Study Published on 2020-12-012022-09-11 Journal: Gynecologic oncology [Category] SARS, 바이오마커, [키워드] active cancer Admission blood cell blood cell count C-reactive protein Cancer cancer patient Clinical outcome clinical outcomes coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 complications COVID-19 infection COVID-19 severity creatinine CRP D-dimer level D-dimer levels death defined disease electronic medical records ferritin Gynecologic cancer Hospitalized ICU admission Infection Inflammation Inflammatory marker inflammatory markers Inflammatory response interquartile range IQR Laboratory laboratory data Lactate marker mechanical ventilation median median age medical records moderate Mortality oncology patient Patient patients patients died Patients with cancer Predictive procalcitonin Prognostic marker Prognostic markers Remission required resulting Severe infection severity significantly significantly higher Tumor white white blood cell count with COVID-19 [DOI] 10.1016/j.ygyno.2020.09.036 PMC 바로가기 [Article Type] Multicenter Study
The potential role of serum angiotensin-converting enzyme in coronavirus disease 2019코로나바이러스 질병 2019에서 혈청 안지오텐신 전환 효소의 잠재적 역할Research Article Published on 2020-11-252022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 바이오마커, [키워드] ACE activity analyzed angiotensin Angiotensin-converting enzyme baseline BMI body mass body mass index clinical condition Clinical data Clinical significance consecutive patient control group controls coronavirus disease Coronavirus disease 2019 COVID-19 demographic Demographic and clinical data hypertension lowest marker no significant difference no significant differences Older Patient patients proportion recruited Remission Result Retrospective study SARS-CoV-2 serum Serum ACE severe group Severe patient severity of COVID-19 subject the disease was measured were recorded [DOI] 10.1186/s12879-020-05619-x PMC 바로가기 [Article Type] Research Article