S1 protein – Page 3 – Communicable Diseases Research

Evaluation of Spike Protein Epitopes by Assessing the Dynamics of Humoral Immune Responses in Moderate COVID-19

중간 정도의 COVID-19에서 체액 면역 반응의 역학을 평가하여 스파이크 단백질 에피토프 평가

Article

Published on 2022-03-182022-09-12
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단,

SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation

SARS-CoV-2 스파이크 단백질 1은 미세혈관 내피 세포 및 보체 시스템을 활성화하여 혈소판 응집을 유도합니다

Article

Published on 2022-03-072022-09-11
Journal: Frontiers in Immunology [Category] SARS, 치료기술,

[키워드] ACE2 Activation addition adhesive molecule aggregate aggregation AMPK amplified Analysis angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 antibody blockade blocking antibody Blot C3a C5a circulating complement Complement activation complement inhibitors complement system complexity conditions coronavirus disease Coronavirus disease 2019 COVID-19 detection element ELISA endothelial Endothelial cell endothelial cells endothelial damage Endothelial dysfunction enzyme evaluated Exocytosis experiment expression human host immunofluorescence incubated induce infect Inflammation Inflammatory inhibitors investigated leading leukocyte lung Microvascular thrombosis microvasculature Mortality multiorgan failure P-selectin performed phenotype Platelet platelet aggregation pro-inflammatory recruitment replicate robust S1 protein SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 spike protein 1 selectin sera severe COVID-19 patient severe COVID-19 patients significant level spike Spike protein System thromboembolic thromboembolic complication thromboembolic complications thrombomodulin thrombosis thrombotic thrombotic complication Thrombotic complications viral infection von Willebrand factor were assessed western blot Western blot analysis
[DOI] 10.3389/fimmu.2022.827146 PMC 바로가기 [Article Type] Article

Rapid electrochemical immunodetection of SARS-CoV-2 using a pseudo-typed vesicular stomatitis virus model

유사형 수포성 구내염 바이러스 모델을 사용한 SARS-CoV-2의 신속한 전기화학적 면역 검출

Article

Published on 2022-03-012022-09-11
Journal: Talanta [Category] MERS, SARS, 진단, 치료기술,

[키워드] alternative Antigen applicability applied binding Biochip biosensor complex Concentration contribute costly COVID-19 COVID-19 pandemic COVID-19 test COVID-19 tests demonstrated diagnostic diagnostic testing diagnostic tests diagnostics Electrochemical impedance spectroscopy equipment exhibiting feasible Immunosensors integration Intensive labor labor-intensive limitation monoclonal antibodies monoclonal antibody overcome Particle performed plague platform point of care Protein pseudovirus Quantitative Rapid Rapid diagnostic testing real-time RT-PCR RT-PCR RT-PCR test RT-PCR tests S1 protein SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 pseudovirus. sensitivity Specific spike Spike protein supply vesicular stomatitis virus VSV
[DOI] 10.1016/j.talanta.2021.123147 PMC 바로가기 [Article Type] Article

Seroprevalence of IgG antibodies against SARS-CoV-2 – a serial prospective cross-sectional nationwide study of residual samples, Belgium, March to October 2020

SARS-CoV-2에 대한 IgG 항체의 Seroprevalence - 잔류 샘플에 대한 연속 전향적 전국 횡단 연구, 벨기에, 2020년 3월~10월

Article

Published on 2022-03-012022-09-11
Journal: Eurosurveillance [Category] MERS, SARS, 진단, 치료기술,

The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression

OM-85 박테리아 용해물은 SARS-CoV-2 수용체 발현을 하향 조절하여 상피 세포의 SARS-CoV-2 감염을 억제합니다

Article

Published on 2022-03-012022-09-11
Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 비임상, 유전자 메커니즘,

[키워드] ACE2 ACE2 protein acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 administration airway airway epithelial cells angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Bacteria Bacterial bacterial lysate binding bronchial epithelial cells caused Cell cell entry cell interactions cell lines coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 downregulated downregulating downregulation Effect enzyme epithelial epithelial cell epithelial cell line epithelial cells expression HEK293T cell host cells human airway human epithelial cell human epithelial cells immunomodulating in vitro infect Infection inhibit inhibited Interaction intestinal kidney lentiviral particles lentivirus lung mRNA Multiple OM-85 organ organs Prevent primary bronchial epithelial cells primary human bronchial epithelial cells protease PROTECT Protein Protein binding protein expression pseudotyped lentiviral particles reduce respiratory infections S protein S1 protein safety profile SARS-CoV-2 SARS-CoV-2 cell infection SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 S1 protein Serine serine 2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity significantly TMPRSS2 Transcription transmembrane transmembrane protease serine 2 treated Treatment were measured
[DOI] 10.1016/j.jaci.2021.11.019 PMC 바로가기 [Article Type] Article

Dynamic of humoral response to SARS-CoV-2 anti-Nucleocapsid and Spike proteins after CoronaVac vaccination

CoronaVac 백신 접종 후 SARS-CoV-2 항-뉴클레오캡시드 및 스파이크 단백질에 대한 체액 반응의 역학

Article

Published on 2022-03-012022-09-11
Journal: Diagnostic microbiology and infectious disease [Category] MERS, SARS, 진단, 치료법,

Evolutionary shift from purifying selection towards divergent selection of SARS-CoV2 favors its invasion into multiple human organs

Article

Published on 2022-02-152022-10-04
Journal: Virus research [Category] COVID19(2023년), MERS, SARS, 변종,

Phage-Displayed Mimotopes of SARS-CoV-2 Spike Protein Targeted to Authentic and Alternative Cellular Receptors

Article

Published on 2022-02-142022-10-28
Journal: Viruses [Category] COVID-19, COVID19(2023년), Fulltext, SARS,

[키워드] accompanied ACE2 ACE2 receptor Alternative receptors Amino acid Analysis antibody bacteriophages binding interaction bioinformatics Cell culture cellular receptor Cluster Combination COVID-19 pandemic displaying element ELISA Evolution FGF1 FGFR3 human cells human coronavirus human host cell Human immune system in viral in vitro in vivo Infection Interaction landscape phage Ligand mechanism mimicking mimotope molecular molecular mechanism molecular mimicry motif mutated NRP1 organs peptide phage phage display phages probe receptor respond S1 protein SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 virus spike Spike protein suggested supported the SARS-CoV-2 the SARS-CoV-2 virus tissue viral spike protein viral variant virus infectivity virus receptors whole organism
[DOI] 10.3390/v14020384 PMC 바로가기 [Article Type] Article

Specific anti-SARS-CoV-2 S1 IgY-scFv is a promising tool for recognition of the virus

Original Article

Published on 2022-02-122022-10-28
Journal: AMB Express [Category] COVID-19,

[키워드] acute respiratory syndrome anti-SARS-CoV-2 antibody Antigen binding BL21 candidate Chicken IgY single chain variable antibody fragment (IgY-scFv) Concentration coronavirus coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 detectable docking study drug E. coli Egg yolk antibody (IgY) expected expressed Human hydrogen bonds IgY technology immunize immunoassay Immunotherapy multiple epitope powerful tool purified RBD reached residue S1 protein SARS-CoV-2 SARS-CoV-2 S1 SARS-CoV-2 S1 protein sensitivity severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Specific specific antibody Spike (S) protein S1 subunit Spread Vaccines virus
[DOI] 10.1186/s13568-022-01355-4 PMC 바로가기 [Article Type] Original Article

In Silico Infection Analysis (iSFA) Identified Coronavirus Infection and Potential Transmission Risk in Mammals

Molecular Biosciences

Published on 2022-02-082022-10-31
Journal: Frontiers in Molecular Biosciences [Category] COVID-19,