Monitoring and managing SARS-CoV-2 evolution in immunocompromised populations면역 저하 집단에서 SARS-CoV-2 진화 모니터링 및 관리Article Published on 2022-05-012022-09-12 Journal: The Lancet. Microbe [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Immunocompromised monitoring Population SARS-CoV-2 evolution [DOI] 10.1016/S2666-5247(22)00061-1 PMC 바로가기 [Article Type] Article
Virus-specific editing identification approach reveals the landscape of A-to-I editing and its impacts on SARS-CoV-2 characteristics and evolution바이러스 특정 편집 식별 접근 방식은 A-to-I 편집 환경과 SARS-CoV-2 특성 및 진화에 미치는 영향을 보여줍니다.Article Published on 2022-03-212022-09-11 Journal: Nucleic Acids Research [Category] SARS, 변종, 유전자 메커니즘, 치료법, [키워드] accelerated activate Affect antigenicity Antiviral approach atlas average cell types Characteristics component components correlated dsRNA event Evidence Evolution expression framework Genome highlight Host hotspot Human IFN response Impact induce infected with SARS-CoV-2 innate immune response intensity MDA5 provide provided regulated resource reveal RNA RNA virus RNA-seq data SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection spike gene the epidemic tissue viral dsRNA viral infectivity Viral RNA [DOI] 10.1093/nar/gkac120 PMC 바로가기 [Article Type] Article
Mutations and Evolution of the SARS-CoV-2 Spike ProteinSARS-CoV-2 스파이크 단백질의 돌연변이와 진화Review Published on 2022-03-192022-09-11 Journal: Viruses [Category] SARS, 변종, 유전자 메커니즘, [키워드] Alpha Alter alterations arising Beta binding can be used cellular entry COVID-19 Critical Delta Effect ENhance Evolution FIVE functions Gamma genesis Health Organization immune Immune escape Infectivity mechanism Mutation new SARS-CoV-2 occur omicron potential mechanism potential mechanisms protein structure SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 spike protein SARS-CoV-2 strain SARS-CoV-2 variants Scientific community spike Spike protein Spike. strain the SARS-CoV-2 the spike protein variant variants viral infection Virus neutralization World Health Organization [DOI] 10.3390/v14030640 PMC 바로가기 [Article Type] Review
OraSure InteliSwab ™ Rapid Antigen Test Performance with the SARS-CoV-2 Variants of Concern-Alpha, Beta, Gamma, Delta, and Omicron알파, 베타, 감마, 델타, 오미크론의 SARS-CoV-2 변종을 사용한 OraSure InteliSwab ™ 신속한 항원 테스트 성능Article Published on 2022-03-062022-09-11 Journal: Viruses [Category] SARS, 변종, 치료기술, 치료법, 치료제, [키워드] Alpha Beta cell culture medium comparable COVID-19 COVID-19 pandemic culture medium Delta diagnostic tests dilution series dilution sery evaluate evaluated FDA function Gamma human population inoculated investigated Lateral flow device limit of detection Limits of detection Lineage no decrease nucleocapsid protein omicron oropharyngeal swab oropharyngeal swabs performance Rapid rapid antigen-detecting test Rapid test Recombinant nucleocapsid protein recorded resulting RNA RNA copies SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 strain sensitivity strain Syrian golden hamster Syrian Golden hamsters Test the SARS-CoV-2 variant variants variants of concern variants of concern. VoC VOCs was determined [DOI] 10.3390/v14030543 PMC 바로가기 [Article Type] Article
Analysis of SARS-CoV-2 synonymous codon usage evolution throughout the COVID-19 pandemicCOVID-19 전염병 전반에 걸친 SARS-CoV-2 동의어 코돈 사용 진화 분석Article Published on 2022-03-012022-09-11 Journal: Virology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] accompanied analysis antagonistic Betacoronavirus bioinformatic analysis codon codon adaptation index codon usage Codon usage bias Codons collected Complete coronavirus COVID-19 COVID-19 pandemic decrease effective Evolution Evolution of SARS-CoV-2 Genome human host humans infect less life-threatening pathogenic Perspective respiratory pathologies SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2. synonymous [DOI] 10.1016/j.virol.2022.01.011 PMC 바로가기 [Article Type] Article
Analysis of Genomic Characteristics of SARS-CoV-2 in Italy, 29 January to 27 March 20202020년 1월 29일부터 3월 27일까지 이탈리아에서 SARS-CoV-2의 게놈 특성 분석Article Published on 2022-02-252022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Analysis authors B.1 center circulation collected Continuous dated phylogeny descendant epidemiological data Evolution Evolutionary rate gene flow gene flows Genome genomes Genomics genomics. highest HPD interval investigated Italian regions Italy lineage B.1 lineages majority molecular Next-generation sequencing NGS North O -glycosylation occurred performed Phylogenetic analysis Phylogeny reported SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage South Spread suggested Surveillance virus [DOI] 10.3390/v14030472 PMC 바로가기 [Article Type] Article
Whole genome sequence analysis showing unique SARS-CoV-2 lineages of B.1.524 and AU.2 in Malaysia말레이시아에서 B.1.524 및 AU.2의 독특한 SARS-COV-2 계통을 보여주는 전체 게놈 서열 분석Research Article Published on 2022-02-252022-09-10 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] age Analysis analyzed approach association caused characterized China circulating clade country COVID-19 COVID-19 case COVID-19 cases D614G variant D614G variants dispersion dominant lineage Evolution Gender genetic diversity genome sequence GISAID Lineage lineages Malaysia Missense mutation nasopharyngeal NCBI oropharyngeal swab pandemic Phylogenetic analysis positive Prevalence real-time RT-PCR reported responsible RT-PCR SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 isolate SARS-CoV-2 isolates SARS-CoV-2 lineage scarcity selected sequence sequenced spike Spike protein Spread statistical analysis submitted sustained the SARS-CoV-2 the spike protein transmembrane domain unique virus WGS [DOI] 10.1371/journal.pone.0263678 PMC 바로가기 [Article Type] Research Article
Predicting the mutational drivers of future SARS-CoV-2 variants of concern우려되는 미래 SARS-CoV-2 변이체의 돌연변이 동인 예측Article Published on 2022-02-232022-09-11 Journal: Science Translational Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] advance Affect Amino acid antibodies applied approach Behavior binding Causal structure contribute covariate driver Effect Efficacy elevated epidemiological Epidemiology Evidence Evolution feature genomic high accuracy host immunity immunology IMPROVE Influenza Mutation natural infection natural infection-derived immunity omicron pandemic pathogen Pathogens predict Predictive Predictive value protein sequence public health Receiver operator characteristic SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 variant shifting Spread surveillance data tested therapeutic therapeutic antibodies Transmissibility Vaccine variants of concern viral fitness viruses waned [DOI] 10.1126/scitranslmed.abk3445 PMC 바로가기 [Article Type] Article
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escapeBrief Report Published on 2022-02-092022-10-31 Journal: Cell Host & Microbe [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Abstract advanced HIV disease antibody Beta Beta variant BNT162b2 convalescent plasma Delta delta variant elicited escaped Evolution example help HIV HIV disease hosts Immune escape Immunity implication infections mapped Mutation neutralization omicron other variants Pfizer predict Prolonged infection regions SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection SARS-CoV-2 strain serological South tested Vaccine variant variants variants of concern virus [DOI] 10.1016/j.chom.2022.01.005 PMC 바로가기 [Article Type] Brief Report
Comparison of SARS-CoV-2 Evolution in Paediatric Primary Airway Epithelial Cell Cultures Compared with Vero-Derived Cell LinesArticle Published on 2022-02-052022-10-28 Journal: Viruses [Category] COVID-19, COVID19(2023년), SARS, [키워드] Adults age airway arising Cell Cell culture cell lines cells changes in children cleavage site co-morbidities Cohort Culture Delta dependent on driving epithelial Evidence Evolution Factor fixation Genetic genetic diversity genotypic growth highlight Host host cell factor host cells human respiratory epithelium in vitro infect isolate isolates LINE morbidity and mortality Mutation nasal passages phenotypic plasticity polybasic primary airway epithelial cells reduced remained respiratory epithelial cells resulting SARS-CoV-2 SARS-CoV-2 evolution several variant spike Strains variant Vero Vero cells viral evolution Virus evolution VoC whole-genome sequencing [DOI] 10.3390/v14020325 PMC 바로가기 [Article Type] Article