Anxiety, Perceived Stress, and Resilience during the COVID-19 Pandemic: Population Estimates of Persons Presenting to a General Practitioner in RomaniaArticle Published on 2021-11-202022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] Anxiety change collected COVID-19 COVID-19 pandemic Critical Depression distress drastic estimate evaluated general practitioner illnesses IMPROVE individual Insomnia intensity loneliness maintain Mental mental health mental health concern Mild moderate occurred Occurrence pandemic Perceived Perceived stress Person Population Practitioner Predictive presenting Psychological interventions recognize Resilience risk Romania scored significant increases in social distancing Stress threshold value [DOI] 10.3390/brainsci11111541 PMC 바로가기 [Article Type] Article
Chemical Exposures Affect Innate Immune Response to SARS-CoV-2화학적 노출은 SARS-COV-2에 대한 선천성 면역 반응에 영향을 미칩니다Article Published on 2021-11-192022-08-31 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료제, [키워드] affected Antigen presentation B-cells cells Chemical chemical compounds Compound COVID-19 COVID-19 pathogenesis death rate death rates dendritic Evidence exposure IFN IFN signaling Immune cell immune cells immune system in silico in silico Approach Infection Innate Interaction knowledge molecular molecular basis molecular mechanism molecular mechanisms monocyte Monocytes open outcome overlapping pathological response pathway Pathways populations predict response resulting SARS-CoV-2 SARS-COV-2 infection signaling pathway significant increases in T-cells the SARS-CoV-2 therapeutic interventions Toxicity xenobiotics [DOI] 10.3390/ijms222212474 PMC 바로가기 [Article Type] Article
Changes in Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Over Time in 10 Sites in the United States, March-August, 20202020년 3월-8월 미국 10개 사이트에서 시간 경과에 따른 중증 급성 호흡기 증후군 코로나바이러스 2 혈청 유병률의 변화Article Published on 2021-11-162022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted age and sex anti-SARS-CoV-2 antibody antibody Antibody Response bootstrap change changes in clinical testing complement confidence Confidence intervals coronavirus coronavirus 2 COVID-19 cumulative cumulative incidence decrease decreases detectable estimate Estimated Evidence evidence of incidence infected with SARS-CoV-2 Infection interval Laboratory majority monitoring New York over performed population level Prevalence reached remained repeated reported respiratory SARS-CoV-2 SARS-COV-2 infection serologic testing serology Seroprevalence serum severe acute respiratory syndrome Coronavirus significant decrease significant increases in Site South statistically significant the United State The United States time United States Utah Washington [DOI] 10.1093/cid/ciab185 PMC 바로가기 [Article Type] Article
Depressive Symptoms Among Older Adults Pre- and Post-COVID-19 PandemicObservational Study Published on 2021-11-012022-10-05 Journal: Journal of the American Medical Directors Associat [Category] SARS, 임상, [키워드] 95% CI Ageing Care center clinically conducted confidence interval COVID-19 COVID-19 pandemic Depression depressive symptom Effect Final Follow-up Health care system implication Improving incidence increase in large cohort longitudinal mental health mental health problem observational study Older pandemic Prevalence Prevent public health measure scale setting shielding significant increases in Symptom Symptoms were measured were used [DOI] 10.1016/j.jamda.2021.09.003 PMC 바로가기 [Article Type] Observational Study
Weight Gain Associated with COVID-19 Lockdown in Children and Adolescents: A Systematic Review and Meta-Analysis소아 및 청소년의 COVID-19 잠금과 관련된 체중 증가: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-10-192022-09-12 Journal: Nutrients [Category] MERS, SARS, 진단, [키워드] 95% CI adolescents BMI body mass index body weight changes in childhood children CINAHL Cochrane Library Comorbidity conducted coronavirus disease COVID-19 COVID-19 pandemic database effective Gain General population heterogeneity increases in Intervention item lockdown Meta-analysis obesity pandemic pediatric Prevalence reduce reported Reporting restrict review searched significant increases in significantly significantly higher systematic review Transmission weight with COVID-19 worsened [DOI] 10.3390/nu13103668 PMC 바로가기 [Article Type] Meta-Analysis
Vaccinating Adolescents and Children Significantly Reduces COVID-19 Morbidity and Mortality across All Ages: A Population-Based Modeling Study Using the UK as an ExampleArticle Published on 2021-10-152022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adolescent age all age groups changes in children clinical outcomes coronavirus COVID COVID-19 COVID-19 disease COVID-19 pandemic debate disease transmission disease transmission model example global public health groups implication Including information mathematical modeling morbidity and mortality Mortality pandemic persist reduce reducing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SEIR significant increases in subsequent transmission of SARS-CoV-2 Vaccinating vaccination Vaccination strategy Vaccine was used [DOI] 10.3390/vaccines9101180 PMC 바로가기 [Article Type] Article
COVID-19 pandemic: Effects of national lockdown on the state of health of patients with type 2 diabetes mellitus in a Moroccan populationObservational Study Published on 2021-10-012022-10-05 Journal: Primary care diabetes [Category] SARS, 임상, [키워드] age average biochemical body mass index Care caused center chronic disease Chronic diseases Complete complications conducted COVID-19 COVID-19 pandemic demographic Diabetes Mellitus Effect El Jadida Health Health status High-density lipoprotein cholesterol hygiene Impact impacted IMPROVE increase in involved lockdown management men Morocco National Patient patients physical activity Prevalence recruited reduce retrospective SARS-CoV-2 significant decrease significant increases in significantly syndrome Systolic blood pressure Type type 2 diabete Type 2 diabetes mellitus were recorded women [DOI] 10.1016/j.pcd.2021.06.007 PMC 바로가기 [Article Type] Observational Study
The Impact of Interferon Beta-1b Therapy on Thyroid Function and Autoimmunity Among COVID-19 Survivors인터페론 베타-1b 치료가 COVID-19 생존자의 갑상선 기능 및 자가면역에 미치는 영향Endocrinology Published on 2021-09-302022-09-12 Journal: Frontiers in Endocrinology [Category] 진단, [키워드] Admission antibodies antibody antibody titres Autoimmunity baseline changes changes in clinician Complete COVID-19 disorder dysfunction evaluate follow-up study function IFN IFN treatment Impact incident increases in indicated interferon Interferon beta-1b median age MONITOR Patient peroxidase positive Result SARS-CoV-2 Seven significant increases in Survivors Thyroid thyroid function thyroid function test Thyroid function tests thyroid gland titre [DOI] 10.3389/fendo.2021.746602 PMC 바로가기 [Article Type] Endocrinology
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potentialSARS-CoV-2 감염 중 단백질 분해를 특성화하여 치료 가능성이 있는 바이러스 절단 부위 및 세포 표적 식별Article Published on 2021-09-212022-09-10 Journal: Nature Communications [Category] SARS, 변종, 신약개발, 유전자 메커니즘, 치료제, [키워드] Anti-viral Antibody testing Antigen benefit biology of SARS-CoV-2 causative agent cell line cellular cellular protease cleavage cleavage site cleavage sites COVID-19 COVID-19 pandemic death dose-dependent reduction drugs targeting event identify in vitro infections inhibit inhibit SARS-CoV-2 mass spectrometry MYLK Papain pathogen protease Protease activity Proteases Protein proteolysis proteolytic cleavage provide resource responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 main protease SARS-CoV-2 replication shown significant increases in siRNA SRC substrate target targets therapeutic potential titres treat tyrosine vaccinate Vaccine Viral viral infection Viral proteins [DOI] 10.1038/s41467-021-25796-w PMC 바로가기 [Article Type] Article
Using Administrative Data to Explore Potentially Aberrant Provision of Virtual Care During COVID-19: Retrospective Cohort Study of Ontario Provincial DataOriginal Paper Published on 2021-09-072022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, SARS, [키워드] ambulatory visits average calculated Canada Care changes in Characteristics Cohort conducted COVID-19 COVID-19 pandemic creating Digital health early stage eligible Evidence female globe Health Health care system insurance International IQR less maintain median objective pandemic Patient patients physician Physicians plan positive correlation rapid increase Result retrospective cohort study significant increases in significantly increased stratified telehealth Telemedicine the mean unique Virtual care virtual health Volume widespread [DOI] 10.2196/29396 PMC 바로가기 [Article Type] Original Paper