Statistical analysis plan – Page 3 – Communicable Diseases Research

Harmonizing Heterogeneous Endpoints in Coronavirus Disease 2019 Trials Without Loss of Information

정보 손실 없이 코로나바이러스 질병 2019 시험에서 이기종 종점 조화

Article

Published on 2021-01-012022-09-11
Journal: Critical Care Medicine [Category] 임상, 치료제,

[키워드] categories category clinical trial clinical trials Clinicians contribute Controlled trial controlled trials core coronavirus disease Coronavirus disease 2019 Course death Descriptive analysis develop discharge Effect Endpoint endpoints event Follow-up health authorities Health Organization heterogeneous Hospital stay Hospitalization include information Loss majority measure measurement mechanical ventilation multiplicity on mechanical ventilation outcome parameter Patient positive individuals primary analysis Probability provide public health authorities Randomized controlled trial Randomized controlled trials reconstructed Registered regulatory agencies statistical statistical analysis Statistical analysis plan Support the patient Treatment treatment effect treatment effects Trial trials while World Health Organization
[DOI] 10.1097/CCM.0000000000004741 PMC 바로가기 [Article Type] Article

Study protocol for CO vid-19 V ascular s ER vice (COVER) study: The impact of the COVID-19 pandemic on the provision, practice and outcomes of vascular surgery

Registered Report Protocol

Published on 2020-12-302022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

Exclusion of enrolled participants in randomised controlled trials: what to do with ineligible participants?

Randomized Controlled Trial

Published on 2020-12-022022-10-04
Journal: BMJ Open [Category] Fulltext, MERS, SARS, 임상,

[키워드] Analysis assumed board Clinical practice creating criteria education & training (see medical education & training) Effect Efficacy eligibility criteria enrolled exclusion include Including Inclusion ineligible intention-to-treat Interpretation intervention effect investigator investigators Lung disease Lung function Measurement error monitoring objective opposite paediatric thoracic medicine participant Participants primary analysis randomisation randomised randomised controlled randomised controlled trial reached reported risk Safety Sample size sensitivity analysis Statistical analysis plan Statistical power statistics & research methods steering committee subsequent Treatment Trial Variation with HIV Zimbabwe
[DOI] 10.1136/bmjopen-2020-039546 PMC 바로가기 [Article Type] Randomized Controlled Trial

A phase 2, open label, multicenter, single arm study of tocilizumab on the efficacy and tolerability of tocilizumab in the treatment of patients with COVID-19 pneumonia (TOCIVID-19 trial): Statistical analysis plan

Research article

Published on 2020-12-012022-10-05
Journal: Contemporary Clinical Trials Communications [Category] 임상, 치료법,

[키워드] 2020-001110-38 added administration All the patient analysis plan approach Chinese Clinical improvement co-primary endpoint COVID-19 COVID-19 pneumonia COVID-19 progression Critical database Efficacy eligible EudraCT evaluate IL-6 receptor include intention-to-treat ITT knowledge lethality rate methodological Mortality multicenter NCT04317092 offered open label Open-label Patient patients with COVID-19 Phase 2 study phase 2 trial Pneumonia prospective cohort provide reduce Registered reported risk Sample size Secondary objective single-arm statistical statistical analysis Statistical analysis plan subject suggested Tocilizumab TOCIVID-19 Tolerability Treatment Trial Validity
[DOI] 10.1016/j.conctc.2020.100665 [Article Type] Research article

Proactive prophylaxis with azithromycin and hydroxychloroquine in hospitalized patients with COVID-19 (ProPAC-COVID): a statistical analysis plan

Update

Published on 2020-10-202022-10-29
Journal: Trials [Category] COVID-19, MERS, SARS,

[키워드] 2019-nCoV age Analysis analyzed antiviral efficacy Azithromycin block chronic lung diseases clinical trial combination therapy data-driven death Detailed statistical analysis plan disease double-blinded evaluate Final hospital Hospital admission Hospitalization hospitalized patient Hydroxychloroquine Infection Infectious diseases intensive care intention-to-treat Intervention ITT ITT analysis modulation non-invasive ventilation outcomes Patient per protocol placebo-controlled Positive test Prevent Primary outcome Prophylaxis randomization Randomized Randomized controlled trial recruitment reduce risk Safety secondary endpoint selective Statistical analysis plan stratified subject symptoms of COVID-19 the patient Treatment Trial with COVID-19
[DOI] 10.1186/s13063-020-04795-0 PMC 바로가기 [Article Type] Update

Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia (COVID STEROID) trial-Protocol and statistical analysis plan

Randomized Controlled Trial

Published on 2020-10-012022-10-05
Journal: Acta Anaesthesiologica Scandinavica [Category] 임상,

[키워드] acute respiratory syndrome all-cause mortality blinded caused clinical clinical trial Confidence intervals coronavirus disease Coronavirus-2 Corticosteroid COVID COVID-19 days alive Effects Evidence hospital Hydrocortisone hypoxic respiratory failure intensive care intention to treat interim analysis International intravenous mechanical ventilation median Mortality on mechanical ventilation outcome oxygen pandemic Patient patients with COVID-19 Placebo populations Primary outcome protocol Quality of life randomised receiving reduce renal replacement therapy reported secondary serious adverse reaction severe hypoxia statistical analysis Statistical analysis plan stratified Support Trial use of corticosteroid viral clearance
[DOI] 10.1111/aas.13673 PMC 바로가기 [Article Type] Randomized Controlled Trial

Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial

Update

Published on 2020-01-032022-10-29
Journal: Trials [Category] Coronavirus, MERS,