The use of mesenchymal stem cells in the process of treatment and tissue regeneration after recovery in patients with Covid-19Review Published on 2021-02-042023-06-16 Journal: Gene [Category] MERS, SARS, [키워드] ARDS, acute respiratory distress syndrome COVID 19 DC, dendritic cell hUCMSC, umbilical cord mesenchymal stem cell hWJCs, Wharton's jelly-derived MSCs IDO, indolelamine 2,3-dioxygenase LIF, leukemia inhibitory factor Mesenchymal stem cells MSC, Mesenchymal Stem Cells NK, natural killer tissue regeneration Treatment [DOI] 10.1016/j.gene.2021.145471 PMC 바로가기 [Article Type] Review
The Systematic Effect of Mesenchymal Stem Cell Therapy in Critical COVID-19 Patients: A Prospective Double Controlled Trial중증 코로나19 환자에서 중간엽 줄기세포 치료의 체계적인 효과: 전향적 이중 대조 시험Controlled Clinical Trial Published on 2021-01-012022-09-11 Journal: Cell transplantation [Category] 유전자 메커니즘, 임상, [키워드] Analysis anti-inflammatory cytokine anti-inflammatory cytokines Apoptosis Biochemical parameters CD16 CD19 CD3 CD4 CD45 CD56 CD8 Cell cellular chemokines clinical manifestation clinical manifestations clinical trial Controlled COVID-19 COVID-19 patient COVID-19 patients Critical critical cases Critically ill critically ill COVID-19 patients critically ill patients CRP level CRP levels cytokine Cytokine storm Cytokines demonstrated died dose Effect evaluate evaluated fibrinogen group groups growth growth factor Growth factors HLA-DR IFNγ IL-10 IL-12 IL-13 IL-17A IL-1ra IL-2 IL-6 immunomodulatory effect immunomodulatory effects intravenously investigated KGF lymphocyte Lymphocyte subsets marker matrix metalloproteinases mechanism of action mesenchymal stem cell Mesenchymal stem cells moderate MSC MSCs Neutrophils NGF overall mortality Patient positive proinflammatory proinflammatory cytokines Prospective reducing mortality separated Serum ferritin significantly statistical STEM stem cell TGF-β the cytokine storm therapy tissue regeneration treated Treatment VEGF [DOI] 10.1177/09636897211024942 PMC 바로가기 [Article Type] Controlled Clinical Trial
Challenges for Mesenchymal Stem Cell-Based Therapy for COVID-19Article Published on 2020-09-292023-07-05 Journal: Drug design, development and therapy [Category] SARS, [키워드] COVID-19 immunomodulation mesenchymal stem cell tissue regeneration [DOI] 10.2147/DDDT.S269407 PMC 바로가기
Implications of Sex Differences in Immunity for SARS-CoV-2 Pathogenesis and Design of Therapeutic InterventionsReview Published on 2020-08-172023-06-15 Journal: Immunity [Category] MERS, SARS, [키워드] COVID-19 immune responses SARS-CoV-2 sex differences tissue regeneration [DOI] 10.1016/j.immuni.2020.08.003 PMC 바로가기 [Article Type] Review
Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumoniaReview Published on 2020-08-142022-10-29 Journal: Stem Cell Research & Therapy [Category] COVID-19, MERS, [키워드] acute respiratory distress acute respiratory syndrome affecting anti-inflammatory effect ARDS article Biomarker carried Cell characteristic Combination coronavirus country cytokines trigger edema effective antiviral treatment Efficacy Exosome Exosomes function Health induce Inflammation Inflammatory cytokines lung management Mesenchymal stem cells new virus outbreak Potential pulmonary fibrosis Result SARS-CoV-2 SARS-CoV-2 pneumonia SARS-CoV-2 virus infection searched secretion selected stem cells syndrome the patient therapeutic tissue regeneration Treatment Vaccine virus pneumonia [DOI] 10.1186/s13287-020-01866-6 PMC 바로가기 [Article Type] Review
Antiviral properties of placental growth factors: A novel therapeutic approach for COVID-19 treatmentArticle Published on 2020-08-062023-06-14 Journal: Placenta [Category] MERS, SARS, [키워드] Anti-inflammatory cellular proliferation immunomodulatory novel coronavirus COVID-19 Placental extract tissue regeneration [DOI] 10.1016/j.placenta.2020.07.033 PMC 바로가기 [Article Type] Article
Recent Updates on Treatment of Ocular Microbial Infections by Stem Cell Therapy: A ReviewReview Published on 2018-02-132024-09-02 Journal: International Journal of Molecular Sciences [Category] 대상포진, [키워드] endophthalmitis Inflammation ocular microbial infections stem cells tissue regeneration [DOI] 10.3390/ijms19020558 PMC 바로가기 [Article Type] Review