Trachea – Page 3 – Communicable Diseases Research

Characterization of dysphagia and laryngeal findings in COVID-19 patients treated in the ICU—An observational clinical study

ICU에서 치료받은 COVID-19 환자에서 편도증 및 후두 소견의 특성화-관찰 임상 연구

Clinical Trial

Published on 2021-06-042022-08-13
Journal: PLoS ONE [Category] MERS, SARS, 임상,

First case of postmortem study in a patient vaccinated against SARS-CoV-2

SARS-CoV-2 예방 접종을 받은 환자의 부검 첫 사례

Case Reports

Published on 2021-06-012022-09-11
Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료법,

[키워드] assigned Autopsy BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine bronchopneumonia cause of death cerebrum Chain Reaction characteristic COVID-19 COVID-19 vaccine Cycle threshold value Cycle threshold values death died elicited examined except for first dose first vaccination heart histology Immunity immunogenicity Immunoglobulin induce kidney liver Lungs molecular morphological feature mucosa nucleocapsid nucleocapsid IgG observé olfactory olfactory bulb organ oropharynx Patient polymerase chain polymerase chain reaction positive Postmortem Protein real-time polymerase chain reaction renal Respiratory failure RT-PCR SARS-CoV-2 significant level spike Spike protein Symptoms tested Trachea Vaccine
[DOI] 10.1016/j.ijid.2021.04.053 PMC 바로가기 [Article Type] Case Reports

SARS-CoV-2 viral dynamics in non-human primates

인간이 아닌 영장류의 SARS-CoV-2 바이러스 역학

Research Article

Published on 2021-03-172022-09-10
Journal: PLoS Computational Biology [Category] SARS, 치료제,

[키워드] absence antiviral treatments association Asymptomatic basic number basic reproduction number burst size clearance Clinical signs cynomolgus macaque cynomolgus macaques cytokine declined develop Efficacy estimate estimates half-life human infection human infections immune markers infected cell infected cells infected with SARS-CoV-2 kinetic mathematical mathematical model median time Mild mild infection nasopharyngeal nasopharynx Non-human non-human primate non-human primates observation observations parameter predict Prevent prophylactic therapy prophylactic treatment reproductive SARS-CoV-2 viral Trachea tracheal Viral viral clearance viral dynamics viral entry viral growth viral infection Viral load viral loads virus
[DOI] 10.1371/journal.pcbi.1008785 PMC 바로가기 [Article Type] Research Article

Prolonged SARS-CoV-2-RNA Detection from Nasopharyngeal Swabs in an Oncologic Patient: What Impact on Cancer Treatment?

종양 환자의 비인두 면봉에서 장기간 SARS-CoV-2-RNA 검출: 암 치료에 어떤 영향을 미칩니까?

Case Reports

Published on 2021-02-082022-09-11
Journal: Current Oncology [Category] MERS, 치료기술,

[키워드] absence affecting association Cancer cancer patient Cancer patients cancer treatment Cell clinical symptom Clinical symptoms complications COVID-19 Culture detection diagnosis of SARS-CoV-2 diagnostic exhibited Impact Infection Isolation lung cancer lung cancer patient lung cancer patients management measure nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs Non-small cell lung cancer overlap pandemic Patient PCR assays Prolonged Radiotherapy remains uncertain risk RT-PCR assay RT-PCR assays SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 viral symptoms of infection the patient Trachea Viral viral culture
[DOI] 10.3390/curroncol28010083 PMC 바로가기 [Article Type] Case Reports

A Transcription Regulatory Sequence in the 5′ Untranslated Region of SARS-CoV-2 Is Vital for Virus Replication with an Altered Evolutionary Pattern against Human Inhibitory MicroRNAs

SARS-CoV-2의 5' 비번역 영역의 전사 조절 서열은 인간 억제 MicroRNA에 대한 변경된 진화 패턴을 가진 바이러스 복제에 중요합니다

Article

Published on 2021-02-042022-09-11
Journal: Cells [Category] MERS, 변종, 신약개발,

K18-hACE2 mice develop respiratory disease resembling severe COVID-19

K18-hACE2 쥐, 심각한 COVID-19와 유사한 호흡기 질환 발병

Research Article

Published on 2021-01-192022-08-13
Journal: PLoS Pathogens [Category] COVID-19, Medicine and Health Sciences,

[키워드] angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 animal model animal models Asymptomatic Author both groups Brain cerebral cortex chemokines clinical manifestation Course COVID-19 COVID-19 pandemic COVID-19 pathogenesis cytokeratin 18 promoter develop disease disease course disease manifestation dose-dependent DPI etiological agent expressing Extrapulmonary hACE2 hippocampus Human human SARS-CoV-2 humanized immunological disease immunological diseases in both group Infection infectious virus titer inoculated inoculation interstitial pneumonia intestinal tract K18 K18-hACE2 mice lethal disease low dose Lower respiratory tract lung Lungs lymphocyte lymphocyte infiltration Macrophage mice Mild mild to moderate moderate disease nasal turbinates Pathogenesis pathology patients Pneumocytes post inoculation progression proinflammatory Pulmonary pathology rapid inflammatory response receptor replication of SARS-CoV-2 reported respiratory Respiratory disease respiratory tract infection resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication Severe case severe cases severe COVID-19 subset Support survival susceptible TCID Th1 Th1 and proinflammatory cytokines/chemokines the SARS-CoV-2 These data Trachea transgenic mice upper and lower respiratory tract upper and lower respiratory tract infection upregulation Viral Viral RNA shedding virus replication virus titers weight loss while
[DOI] 10.1371/journal.ppat.1009195 PMC 바로가기 [Article Type] Research Article

Transnasal humidified rapid-insufflation ventilatory exchange (‘THRIVE’) in the coronavirus disease 2019 pandemic

코로나바이러스 질병 2019 대유행에서 비강 가습 급속 주입 환기 교환('THRIVE')

Short Communications

Published on 2021-01-072022-09-12
Journal: The Journal of laryngology and otology [Category] MERS, 진단,

On the whereabouts of SARS-CoV-2 in the human body: A systematic review

인체 내 SARS-CoV-2의 행방: 체계적인 검토

Research Article

Published on 2020-10-302022-08-13
Journal: PLoS Pathogens [Category] Biology and Life Sciences, COVID-19, MERS, SARS,

[키워드] ACE2 ACE2 entry-receptor ACE2 receptor addition aligned Blood body fluid body fluids Brain breast milk caused cerebrospinal fluid complex interplay component concerning consequence Containment correlated COVID-19 patients detect infectious virus Diagnosis distribution entry receptor Evidence expressed expression data expression level expression levels focus foundation heart highlight Host human body human host human population human tissue human tissues Impact implicates the presence improve diagnostics Infectious virus information intestines kidneys knowledge lung Lungs male genital male genitals Mucus multiple organ multiple organs multiple tissue multiple tissues observé organotropism of SARS-CoV-2 pandemic pandemic virus performed pharynx Proteins provide researcher RNA Saliva SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 entry receptor SARS-CoV-2 pathogenesis SARS-CoV-2 patients Scientific community Semen Single Cell Spread Stool systematic review These data Trachea Treatment treatment of COVID-19 patients Urine vessels Viral viral presence viral shedding viral shedding in body fluids virus
[DOI] 10.1371/journal.ppat.1009037 PMC 바로가기 [Article Type] Research Article

Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2

SARS-CoV-2의 진입 수용체인 지오텐신 전환 효소 2의 생물정보학적 특성화

Research Article

Published on 2020-10-282022-08-13
Journal: PLoS ONE [Category] MERS, SARS, 유전자 메커니즘,

[키워드] ACE2 ACE2 gene ACE2 mRNA age and gender Analysis angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 angiotensin-converting enzyme 2 binding site Bioinformatic bioinformatics caused Cell cell type cell types ciliary classical club COVID-19 COVID-19 epidemic duodenum endothelial entry receptor enzyme epithelial epithelial cells expressed expression functions Gene ontology analysis goblet goblet cells Health Organization highest immunohistochemistry include indicated interferon-stimulated response element International IRF8 IRF9 kidney lung Novel coronavirus novel coronavirus SARS-CoV-2 Ontology organ pandemic positive predict promoter promoters Protective public health emergency Regulation Renin renin-angiotensin system respiratory respiratory tract SARS-CoV-2 signal small intestine Stat1 suggested target cell target cells Testis Trachea transcription factor transcriptional regulation Vascular vessel World Health Organization
[DOI] 10.1371/journal.pone.0240647 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study

과일박쥐, 흰 족제비, 돼지, 닭의 SARS-CoV-2: 실험적 전염 연구

Article

Published on 2020-09-012022-09-11
Journal: The Lancet. Microbe [Category] Fulltext, SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animal Animal host animals antibody antivirals Autopsy bat bats Characteristics China Clinical sign Clinical signs collected Contact coronavirus detectable Direct direct contact faece ferret ferrets food Histopathology Host human infection human infections immunofluorescence assay immunohistochemistry indirect immunofluorescence infected intranasally Infection infections inoculated inoculation intranasally lung lymphatic tissue nasal Nasal cavity nasal washe Nasal washes neutralising nine nucleic acid nucleic acid extraction Olfactory epithelium oral swab oral swabs organ Oropharyngeal pandemic pig PIGS Presence Prominent Quantitative Quantitative RT-PCR reactive rectal swab Rectal swabs Replication Reservoir host respiratory rhinitis risk RNA Rousettus RT-PCR RT-qPCR SARS-CoV-2 seroconverted Severe case severe cases Spread susceptible Swab swabs TCID titre Trachea Transmission upper respiratory tract Vaccine various tissue Viral Viral antigen viral genome Viral RNA viral RNA load Viral transmission virus virus detection Virus neutralisation virus replication Virus shedding was tested zoonotic
[DOI] 10.1016/S2666-5247(20)30089-6 PMC 바로가기 [Article Type] Article