Rapid and Effective Vitamin D Supplementation May Present Better Clinical Outcomes in COVID-19 (SARS-CoV-2) Patients by Altering Serum INOS1, IL1B, IFNg, Cathelicidin-LL37, and ICAM1신속하고 효과적인 비타민 D 보충은 혈청 INOS1, IL1B, IFNg, Cathelicidin-LL37 및 ICAM1을 변경하여 COVID-19(SARS-CoV-2) 환자에서 더 나은 임상 결과를 제시할 수 있습니다Article Published on 2021-11-122022-09-10 Journal: Nutrients [Category] MERS, SARS, 유전자 메커니즘, [키워드] 25OHD 25OHD level Acute respiratory failure Altering analyzed Better Biomarkers Blood Cathelicidin cathelicidin-LL37 clinical clinical outcomes Comorbidities Comorbidity conducted Correlation analysis COVID-19 COVID-19 case COVID-19 cases COVID-19 treatment cytokine decreased mortality effective Effectiveness evaluate evaluated healthy individual Hospital stay Hospitalization ICAM1 IFNg IL1B increased risk indicated metabolism mortality rate outcomes parameter potential mechanism potential mechanisms present Prospective Study Rapid Regulation SARS-CoV-2 serum serum biomarker Serum level serum levels serum vitamin D significantly specific serum Treatment Treatment protocol Vitamin D Vitamin D Metabolism Vitamin D supplementation Vitamin D3 [DOI] 10.3390/nu13114047 PMC 바로가기 [Article Type] Article
The effect of vitamin D, magnesium and zinc supplements on interferon signaling pathways and their relationship to control SARS-CoV-2 infectionReview Published on 2021-11-082022-11-01 Journal: Clinical and Molecular Allergy : CMA [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome addition adjuvant therapy Antiviral association Community coronavirus COVID-19 cytokine Cytokine storm Defense disease risk genetic mutation Host IFN IFN signaling immune system indicated infiltration interferon interferon signaling investigated leukocyte Magnesium modulation occur pathway patients Prevent raised reduce reduced reported SARS-CoV-2 SARS-COV-2 infection severity of COVID-19 signaling pathway strain Symptom syndrome synergistic treat Treatment Treatment protocol Vaccine viral infection Vitamin D Zinc [DOI] 10.1186/s12948-021-00161-w PMC 바로가기 [Article Type] Review
Unilateral Diaphragmatic Paralysis in a Patient With COVID-19 PneumoniaInternal Medicine Published on 2021-11-062022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Admission clinically Complication coronavirus COVID-19 COVID-19 pneumonia diaphragmatic disease Dyspnea febrile help hospital lung nasal Neuroinvasive neurologic neurologic complication oxygen support paralysis parenchymal Patient Pneumonia presenting SARS-CoV-2 self-resolving shown Treatment protocol Unilateral unilateral diaphragmatic paralysis [DOI] 10.7759/cureus.19322 PMC 바로가기 [Article Type] Internal Medicine
SARS-CoV-2 Infection in Kidney Transplant Recipients: A Single-Centre Study of 20 Cases from IndiaResearch Article Published on 2021-11-052022-10-29 Journal: International Journal of Nephrology [Category] COVID-19, [키워드] Administered AKI antiviral drug approved clinical Clinical features Consensus COVID-19 develop Dexamethasone effective Evidence expired General population hospitalisation Hospitalized hospitalized patient hospitalized patients HRCT hypoxia Immunosuppression incidence increased risk India Infection mechanical ventilation mild hypoxia Modification mortality rate NIV outcome Patient patients protocol protocols recipient recovered completely reduced Remdesivir renal required Result robust RRT Safe SARS-CoV-2 SARS-COV-2 infection second wave Severe infection severity Spread still hospitalized Support survival rates therapeutic Transplant Treatment protocol with COVID-19 [DOI] 10.1155/2021/2243095 PMC 바로가기 [Article Type] Research Article
Synthesis and characterization of new thiazole-based Co(II) and Cu(II) complexes; therapeutic function of thiazole towards COVID-19 in comparing to current antivirals in treatment protocolResearch article Published on 2021-11-012022-10-05 Journal: Journal of Molecular Structure [Category] 치료법, 치료제, [키워드] analogue analogues Antiviral antiviral activity antiviral role carried characterized complex complexes COVID-19 COVID-19 drugs COVID-19 pandemic DFT drug drugs effective Efficiency ESR form in-silico Interaction ions Ligand metal ions molecular docking Neutral outcome pandemic pharmacophore profile Proteins suggested Support synthesis therapeutic Thiazol complexes Treatment Treatment protocol while [DOI] 10.1016/j.molstruc.2021.130961 [Article Type] Research article
Efficacy of Ceftazidime and Cefepime in the Management of COVID-19 Patients: Single Center Report from EgyptArticle Published on 2021-10-202022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] addition age Antibiotics Antiviral carried cefepime Ceftazidime center complex complications COVID-19 death Dexamethasone dose enzyme FIVE Follow-up Glucocorticoids group in silico inhibitory activity M pro MPro males management management protocol moderate Patient patients patients treated patients with COVID-19 performed replaced report SARS CoV-2 Severe case Side effects steroid the patient the WHO treated Treatment Treatment protocol were recorded were used [DOI] 10.3390/antibiotics10111278 PMC 바로가기 [Article Type] Article
Challenges in Steroid and Anticoagulant Therapy in Severe COVID-19 Pneumonia: A Prospective StudyArticle Published on 2021-10-062022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] acute kidney adopted Anti-inflammatory Anticoagulant assessment Assiut University Hospital bleeding C reactive protein challenge Clinical outcome comorbid diseases Complication conducted Corticosteroid Corticosteroids COVID-19 COVID-19 patient D-dimer discharge disease enoxaparin ferritin flexible Follow-up group hematoma highest hospital Hospital stay ICU In-hospital lowest Lung fibrosis Methylprednisolone mortality rate multivariable Myocardial infarction outcome Oxygen therapy Patient patient group patients predictor Prospective protocol RT-PCR severe COVID-19 patient Severe COVID-19 pneumonia severe pneumonia significant difference standard treatment steroid Study design therapeutic therapy three group Treatment Treatment protocol two groups was performed [DOI] 10.3390/antibiotics10101214 PMC 바로가기 [Article Type] Article
Clinical characteristics and treatment outcomes of severe (ICU) COVID-19 patients in Saudi Arabia: A single centre studyResearch article Published on 2021-10-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 치료법, 치료제, [키워드] age Antibiotic treatment Antibiotics antimalarial Antiviral Bilateral Characteristics clinical Comorbidity conducted coronavirus coronavirus disease cough COVID-19 COVID-19 patient D-dimer diabetics effort epidemiological feature Fever headache hospital Hydroxychloroquine hypertensive ICU ICU patient IMPROVE infiltration information intensive care intensive care unit Laboratory Laboratory results lymphopenia males median mortality rate objective outcomes oxygen saturation Patient patients presenting Prevent radiological ranged reduce required Result retrospective cohort study risk Saudi Arabia severe symptoms severity Smokers sore throat Symptom the disease the patient therapy Treatment Treatment outcome Treatment protocol vital sign [DOI] 10.1016/j.jsps.2021.08.008 [Article Type] Research article
COVID-19 pneumonia in kidney transplant recipients: A promising treatment algorithm in the absence of a disease-specific drug신장 이식 환자의 코로나19 폐렴: 질병별 약물 부재 시 유망한 치료 알고리즘Article Published on 2021-10-012022-09-12 Journal: Journal of medical virology [Category] MERS, SARS, 진단, [키워드] absence administration Algorithm Anti-inflammatory anti-inflammatory treatment Antibiotics antibody applied CCT Chest computed tomography Clinical outcome composed Consensus coronavirus disease COVID-19 Deceased diagnosed with COVID-19 disease evaluated examined Favipiravir High-dose Hospitalized hospitals immunosuppressive interleukin-6 receptor Intravenous immunoglobulin intravenous methylprednisolone IVIG kidney kidney transplant kidney transplant recipient Kidney transplantation management Modification mortality rate Nonresponder Organ transplant outcomes parameter Patient patients patients with pneumonia Pneumonia protocol provided receive required respiratory Respiratory failure Safe Severe COVID-19 pneumonia significantly therapy Tocilizumab treated Treatment Treatment protocol were given with COVID-19 [DOI] 10.1002/jmv.27110 PMC 바로가기 [Article Type] Article
A Bayesian estimate of the early COVID-19 infection fatality ratio in Brazil based on a random seroprevalence survey무작위 혈청 유병률 조사를 기반으로 한 브라질의 초기 COVID-19 감염 사망률에 대한 베이지안 추정Article Published on 2021-10-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] 95% CI antibody average baseline value Bayesian Brazil country COVID-19 COVID-19 infection dataset datasets estimate estimates fatality health system IFR IgG antibody include Infection medication medications Prevalence random SARS-CoV-2 seroprevalence survey significantly subsequent Treatment protocol treatment protocols [DOI] 10.1016/j.ijid.2021.08.016 PMC 바로가기 [Article Type] Article