Drug delivery systems for RNA therapeutics Reviews Published on 2022-01-042022-10-05 Journal: Nature reviews. Genetics [Category] 유전자 메커니즘, [키워드] approval Cell cell types circumvent drug delivery system Efficiency Gene therapy highlighting immune responses IMPROVE limitation molecular mechanism Research RNA RNA therapeutics target cell therapeutic vectors [DOI] 10.1038/s41576-021-00439-4 [Article Type] Reviews
Intersections between pneumonia, lowered oxygen saturation percentage and immune activation mediate depression, anxiety, and chronic fatigue syndrome-like symptoms due to COVID-19: A nomothetic network approachResearch article Published on 2022-01-012022-10-05 Journal: Journal of affective disorders [Category] SARS, 바이오마커, [키워드] accompanied ACE2 activated affective albumin Analysis Anomaly Anxiety approach association Biomarker Chest computed tomography chronic Chronic fatigue chronic fatigue syndrome consolidation COVID-19 COVID-19 patient CRP Depression depressive Effect enzyme explain explained fibromyalgia ground glass opacities healthy control IL-10 IL-6 immune activation immune response Inflammation Insomnia lung lesion lung lesions Major depression neuro-immune Neuropsychiatric oxygen saturation Partial Pathways Pneumonia psychiatry Result SARS-COV-2 infection SpO2 Symptom Symptoms vector vectors were assessed [DOI] 10.1016/j.jad.2021.10.039 [Article Type] Research article
Indirect impact of COVID-19 on the incidence rates of vector-borne diseases in MexicoCOVID-19가 멕시코의 매개체 매개 질병 발생률에 미치는 간접적 영향Article Published on 2022-01-012024-08-08 Journal: Gaceta médica de México [Category] 말라리아, [키워드] Case fatality rate endemic regions incidence rate Regiones endémicas Tasa de incidencia Tasa de letalidad Vectores vectors [DOI] 10.24875/GMM.M22000712
A smartphone-based visual biosensor for CRISPR-Cas powered SARS-CoV-2 diagnosticsCRISPR-Cas 기반 SARS-CoV-2 진단을 위한 스마트폰 기반 시각 바이오센서Article Published on 2022-01-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aggregation applied changes clinical clinical samples clinically color coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR CRISPR-Ca CRISPR-Cas12a cross-reactivity Degradation detect develop diagnostics evidenced eye gold Gold nanoparticle Gold nanoparticles imperative limit of detection nucleic acid nucleic acids pandemic positive provide provided pseudovirus pseudoviruses qPCR RNA robust SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 pseudoviruses selective single-stranded DNA Smartphone Smartphone-based diagnostics the SARS-CoV-2 transcribed triggered vectors Visual Visual biosensor. [DOI] 10.1016/j.bios.2021.113646 PMC 바로가기 [Article Type] Article
The vectors of Plasmodium knowlesi and other simian malarias Southeast Asia: challenges in malaria eliminationarticle Published on 2021-12-312024-09-01 Journal: Advances in parasitology [Category] 말라리아, [키워드] Bionomics Leucosphyrus group of Anopheles Simian malaria Transmission vectors [Article Type] article
CGENet: A Deep Graph Model for COVID-19 Detection Based on Chest CTArticle Published on 2021-12-272022-10-28 Journal: Biology [Category] COVID-19, [키워드] Accuracy addition Algorithm Algorithms assist average backbone boost Chest computed tomography Chest CT images chose Classifier computer-aided diagnosis Convolutional neural network COVID-19 COVID-19 diagnosis COVID-19 samples dataset deep detection detection system determine diagnosis of COVID-19 effective evaluated extreme extreme learning machine feedforward neural network graph Graph neural network introduced mechanism Model produced simple Spread transfer transfer learning vectors [DOI] 10.3390/biology11010033 PMC 바로가기 [Article Type] Article
Did Climate Change Influence the Emergence, Transmission, and Expression of the COVID-19 Pandemic?Medicine Published on 2021-12-082022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] activity affected affecting bat caused change Climate Climate change Community condition coronavirus COVID-19 COVID-19 pandemic emergence environmental factor Epidemics expression Factor Health homeostasis Host host immunity humans Infection influence Novel coronavirus outcome pandemic Pandemics problem reservoirs respiratory survived temperature Transmission vectors virus [DOI] 10.3389/fmed.2021.769208 PMC 바로가기 [Article Type] Medicine
A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters생약독화 파라인플루엔자 바이러스 매개 SARS-CoV-2 백신의 단일 비강 투여는 햄스터를 보호합니다423 Published on 2021-12-072022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] Coronavirus, SARS, 진단, [키워드] age all age groups antibody Antigen B.1.1.7 B.1.351 children chimeric clinical evaluation contribute COVID-19 dose effort evaluated exhibited Express expressed expressing expression fold generally mild hamster hamsters IgA IgG immunization immunogenic Infant Infants intranasal intranasal immunization intranasally Lineage lineages lung Lungs manuscript moderate morbidity nasal tissue neutralization Neutralizing activity parainfluenza parainfluenza virus parainfluenza virus 3 parainfluenza virus vaccines pediatric prefusion PROTECT Protective Receptor binding domain replicated Replication respiratory tract restrict robust S protein S-2P SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 replication SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 vaccine SARS-CoV-2 vaccines serum Significance significantly higher Single-dose Spike protein TCID the SARS-CoV-2 titers Transmission dynamics undetectable Vaccine vaccine candidate vaccine vector vector vectors virus was reduced weight loss [DOI] 10.1073/pnas.2109744118 PMC 바로가기 [Article Type] 423
Rodent hosts and flea vectors in Brazilian plague foci: a reviewReview Published on 2021-11-012023-06-22 Journal: Integrative zoology [Category] 조류인플루엔자, [키워드] Fleas plague rodents Transmission vectors [DOI] 10.1111/1749-4877.12480 [Article Type] Review
Distinct patterns of whole blood transcriptional responses are induced in mice following immunisation with adenoviral and poxviral vector vaccines encoding the same antigen전혈 전사 반응의 뚜렷한 패턴은 동일한 항원을 암호화하는 아데노 바이러스 및 poxviral 벡터 백신으로 예방 접종 후 마우스에서 유도된다.Research Published on 2021-10-302022-09-10 Journal: BMC Genomics [Category] MERS, SARS, 유전자 메커니즘, [키워드] adaptive immune responses Adenovirus Administered Analysis Antigen antigens cell activation cellular ChAdOx1 change changes characterisation Combination combinations Comparative analysis COVID-19 vaccine Diseases effective Emerging infectious diseases Epigenetic evaluate Express expression Gene Expression gene signature Genes greater heterologous prime-boost human clinical trial human clinical trials humoral immune response immune responses Infectious diseases innate immune involved Killer cell leads magnitude mechanism MHC class I mice natural killer natural killer cell Pathogens pathway Protective protective response protective responses Rapid induction regimen Regulation response Result significant enrichment single dose supplementary material T cell These data TLR2 transcriptional transcriptional response transgene type I interferon type I interferon genes Vaccine vaccine construct vaccine platform valuable resource vector vectors Viral Viral vector vaccine was used Whole blood [DOI] 10.1186/s12864-021-08061-8 PMC 바로가기 [Article Type] Research