Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptationResearch Advance Published on 2021-04-092022-10-31 Journal: eLife [Category] COVID-19, SARS, [키워드] airway Airway organoids Calu-3 can be used Cell Cell culture cell culture adaptation cell culture conditions cell line COVID-19 Culture expresse facilitate facilitated furin cleavage site Human human airway human airway cell knowledge MBCs multibasic cleavage site mutate Prevent SARS-CoV-2 SARS-CoV-2 propagation Serine serine protease serine proteases specimens the spike protein VeroE6 cells viral mutation virus [DOI] 10.7554/eLife.66815 PMC 바로가기 [Article Type] Research Advance
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interfaceSARS-CoV-2 중화 인간 재조합 항체는 RBD-ACE2 인터페이스에서 결합하는 팬데믹 전 건강한 기증자로부터 선택됩니다Article Published on 2021-03-112022-09-10 Journal: Nature Communications [Category] SARS, 변종, 진단, 치료제, [키워드] ACE2 ACE2 receptor ACE2-RBD acute respiratory disease anti-SARS-CoV-2 antibody Antibody therapy binding Biotechnology candidate caused Cell cell entry coronavirus COVID-19 enzyme expressing Expression systems healthy healthy donor human ACE2 human donor IgG independent Infection Infectious diseases inhibit Interaction material naïve neutralization neutralize Neutralizing offer pandemic phage RBD RBD-ACE2 receptor Receptor binding domain recognizing recovering patient Respiratory disease S1 subunit sarbecovirus SARS-CoV-2 SARS-CoV-2 virus SARS-CoV-2 virus infection scFv selected Spike protein subsequent the S1 subunit the spike protein therapeutic unique VeroE6 cells Viral viral infection viral spike protein virus virus infection [DOI] 10.1038/s41467-021-21609-2 PMC 바로가기 [Article Type] Article
In Vitro Data of Current Therapies for SARS-CoV-2Article Published on 2020-01-012023-07-05 Journal: Current medicinal chemistry [Category] SARS, [키워드] ACE2 receptor In vitro studies SARS-CoV-2 (COVID-19) Therapies Vaccines VeroE6 cells [DOI] 10.2174/0929867327666200513075430