Sorption of SARS-CoV-2 Virus Particles to the Surface of Microplastics Released during Washing ProcessesArticle Published on 2021-12-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] contribute Efficiency fiber highest microfibers microplastics Occurrence Particle released Research SARS-CoV-2 Sorption sorption of virus particles surface virus virus particle washing washing processes wastewater [DOI] 10.3390/ijerph19010281 PMC 바로가기 [Article Type] Article
Flagellin From Pseudomonas aeruginosa Modulates SARS-CoV-2 Infectivity in Cystic Fibrosis Airway Epithelial Cells by Increasing TMPRSS2 ExpressionImmunology Published on 2021-12-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] Activation AEC airway angiotensin-converting enzyme 2 Calu-3 cell calu-3 cells CFTR chronic respiratory disease coronavirus disease Course COVID-19 COVID-19 severity COVID19 Critical Cystic cystic fibrosis deficiency develop epithelial cell Factor fibrosis flagella flagellin Health host protease identify immune response increase Increasing infect Infection Infectivity MAPK modulation P. aeruginosa Patient patients populations protease Protein Pseudomonas aeruginosa receptor recommendation reduce released risk of COVID-19 SARS-CoV-2 SARS-COV-2 infection susceptibility TLR5 TMPRSS2 TMPRSS2 expression transmembrane transmembrane serine protease urgency virus particle [DOI] 10.3389/fimmu.2021.714027 PMC 바로가기 [Article Type] Immunology
Susceptibility of Dog, Hamster, and Mouse Cells to the Replication-Competent Adenovirus 11p E1/E3 Green Fluorescence Protein Vector Has Implications for the Selection of Animal Vaccine ModelsMicrobiology Published on 2021-10-272022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Ad5 Adenovirus animal animal cells animal model Antigen can be used candidate CD46 Cell cell line cell lines cellular receptor CHO cells Critical cytotoxicity DNA replication dog dose E1/E3 vector Efficacy Express expressed expression Fluorescence generate GFP GFP expression green hamster host cell Human in vitro experiments infect infecting Infection manifested MDCK cells Model mouse not express Protein qPCR assay RCAd11pGFP SARS-CoV-2 vaccine Selection specificity susceptibility the vaccine Trial undetectable Vaccine Vaccines vector viral DNA virus virus infection virus particle [DOI] 10.3389/fmicb.2021.698999 PMC 바로가기 [Article Type] Microbiology
Search for RNA aptamers against non-structural protein of SARS-CoV-2: Design using molecular dynamics approachResearch Published on 2021-10-122022-10-28 Journal: Beni-Suef University Journal of Basic and Applied Sciences [Category] COVID-19, [키워드] Activation antiviral target approach aptamer binding binding affinity complex conformational docking downstream Dynamics effective ENCODE enzyme function Genome H-bond HADDOCK score Host identify investigated lack less methyltransferase molecular molecular dynamics Molecular dynamics simulation mRNA non-structural protein nsp10 nucleocapsid outbreak Protein recent replicase polyproteins respiratory Result reveal RNA RNA genome SARS-CoV-2 screened Spike proteins stability supplementary material susceptible the disease turn Vaccine Viral RNA virus particle [DOI] 10.1186/s43088-021-00152-5 PMC 바로가기 [Article Type] Research
Improving human coronavirus OC43 (HCoV-OC43) research comparability in studies using HCoV-OC43 as a surrogate for SARS-CoV-2Article Published on 2021-10-092022-10-04 Journal: Journal of virological methods [Category] MERS, SARS, 치료기술, 치료제, [키워드] accompany acute respiratory syndrome added African green monkey analyzed antibodies antibody concentration approach biosafety BSL-3 Cell cell line cells Colon cancer Combination common cold comparability complicate conducted coronavirus counter CPE Culture Cytopathic effect days post infection demonstrated described droplet fibroblast Flow virometry growth Growth Curve HCoV-OC43 human coronavirus human coronavirus OC43 human lung Improving Infection infectious dose investigated kidney less multiplicity of infection pandemic parameter Plaque assay produced quantification quantified reached reducing reproducibility required Research respiratory aerosol Respiratory system Sample SARS-CoV-2 Sartorius Seven Standardization target TCID these cell tissue transmitted Vero E6 Vero E6 cell virion virus particle Virus titration [DOI] 10.1016/j.jviromet.2021.114317 PMC 바로가기 [Article Type] Article
Viral detection and identification in 20 min by rapid single-particle fluorescence in-situ hybridization of viral RNAArticle Published on 2021-10-012022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] added biological sample Biological techniques Biomarkers COVID-19 pandemic cultures diagnostic Diseases exacerbate Genome Infectious Bronchitis Virus Influenza virus lab Microbiology Nanoscience and technology nasal Optics and photonics Patient protocol purification risk SARS-CoV-2 throat swab viral outbreak Viral RNA virus virus detection virus particle [DOI] 10.1038/s41598-021-98972-z PMC 바로가기 [Article Type] Article
Assembly of Biomolecular Gigastructures and Visualization with the Vulkan Graphics APIArticle Published on 2021-09-162022-10-29 Journal: Journal of Chemical Information and Modeling [Category] COVID-19, MERS, SARS, [키워드] Algorithm API assembly automated block bouton building can be used cells conformations Creative Common displaying downloaded Essential Giant GPU Graphics HIV implementation introduced limit memory molecular Molecular dynamics simulation platform presynaptic reduce reduced required SARS-CoV-2 significantly Structure structures View virus particle Visualization [DOI] 10.1021/acs.jcim.1c00743 PMC 바로가기 [Article Type] Article
Elimination of SARS-CoV-2 along wastewater and sludge treatment processes폐수 및 슬러지 처리 공정에 따른 SARS-CoV-2 제거Article Published on 2021-09-012022-09-11 Journal: Water research [Category] SARS, 치료기술, [키워드] acute respiratory syndrome coronavirus affinity applied bacteriophage Chain Reaction characterized chlorination comparability coronavirus 2 COVID-19 COVID-19 incidence demonstrated digestion Effectiveness eliminated Elimination evaluate feces genetic material genomic RNA hydrolysis Laboratory Occurrence participated plant polymerase chain polymerase chain reaction positive result processed Quantitative question raised reduced reducing reduction Region reliability removal respiratory reverse transcriptase RNA RNA copy RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA secondary Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly Sludge transcriptase treated Treatment Viral RNA virus virus particle virus particles virus RNA was done wastewater water Water treatment WWTP [DOI] 10.1016/j.watres.2021.117435 PMC 바로가기 [Article Type] Article
Electrocardiographic manifestations of COVID-19: Effect on cardiac activation and repolarizationResearch article Published on 2021-08-062022-10-05 Journal: EClinicalMedicine [Category] 바이오마커, [키워드] abnormality Activation administration Analysis baseline Biomarker BNP cardiac involvement control group COVID-19 COVID-19 disease discharged disease course disease severity drugs ECG Effect electrocardiogram elevated evaluated finding foundation Francis funding heart tissue ICU identify increase in Inpatient interval Intervention manifestation marker Mortality multivariable analysis NT pro-BNP NTPRO BNP Patient patients with COVID-19 patients with influenza peptide performed predict predicted predictor progression Prolonged QRS QT interval QTc QTc interval QTC prolongation Repolarization reported Retrospective study SAR-CoV-2 troponin troponin level virus particle was used were measured with COVID-19 [DOI] 10.1016/j.eclinm.2021.101057 [Article Type] Research article
Coronavirus disease 2019 morbid pulmonary pathology: What did we learn from autopsy examinations?Review Article Published on 2021-08-042022-10-29 Journal: Journal of Clinical and Translational Research [Category] COVID-19, [키워드] African alteration Autopsy case sery caused Cell cell types change Clinical outcome contributed coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case Deceased Diffuse alveolar damage electron microscopy English epidemiological explained facilitate Google Scholar hallmark histopathological individual infected patients Inflammatory knowledge lung Lymphocytes majority mononuclear cells morbidity and mortality neutrophil pathology pathophysiology patients performed Pneumocytes populations Postmortem pulmonary pulmonary pathological Pulmonary pathology pulmonary thrombi radiological Relevance reported Research respiratory manifestation Therapies type 2 pneumocyte virus particle was performed with COVID-19 PMC 바로가기 [Article Type] Review Article