Antiviral drugs for coronavirus disease 2019 (COVID-19): a systematic review with network meta-analysis코로나 바이러스 질병 2019를위한 항 바이러스 약물 (Covid-19) : 네트워크 메타 분석을 통한 체계적인 검토Meta-Analysis Published on 2022-02-012022-08-31 Journal: Expert review of anti-infective therapy [Category] COVID19(2023년), meta-analysis, SARS, 임상, 치료제, [키워드] all-cause mortality Antiviral antiviral drug antiviral drugs antivirals baloxavir baloxavir marboxil best Clinical practice comparison conducted controlled trials coronavirus disease COVID-19 diarrhea drug Efficacy Evidence hospitalized COVID-19 patients Interpretation Lopinavir nausea Network meta-analysis outcome outcomes patients Placebo Probability progression Randomized Randomized controlled trial Randomized controlled trials RCT RCTs Remdesivir retrieved Ritonavir Safety searched significantly increased Support systematic review Treatment triazavirin Viral viral clearance vomiting [DOI] 10.1080/14787210.2021.1961579 PMC 바로가기 [Article Type] Meta-Analysis
Acute Bacterial Hemorrhagic Pyelonephritis in a COVID-19 Patient With a History of Hypothyroidism: A Case ReportEmergency Medicine Published on 2022-01-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accompanied ACE2 acute kidney Affect Alter Angiotensin-converting enzyme Anosmia anti-inflammatory mediator Bacterial binding C-reactive protein Case report chest X-ray chills chronic cardiovascular Combination Comorbidity Computerized tomography Concentration condition COVID-19 COVID-19 patient COVID-19 patients creating Critical CT scan cytokine Cytokine storm syndrome dependent on diagnosis of COVID-19 diaphoresis disease dose dysregulation dysuria elevated Escherichia coli expressed Factor fatality female fibrinogen FIVE growth headache Health Hematuria Hemorrhagic high risk history Hormones host cells hydronephrosis Hypothyroid Hypothyroidism Infection Inflammation initial Injury Interaction kidney kidney stone Laboratory Lungs metabolic pathways moderate morbidity Mortality nausea novel coronavirus SARS-CoV-2 obesity organ pandemic patchy Pfizer positive prevalence of COVID-19 progression pyelonephritis receiving renal report Respiratory disease Respiratory illness risk factor SARS-CoV-2 SARS-CoV-2 infections Severe case severe immunosuppression severity shown symptomatic tested the SARS-CoV-2 Thyroid unique ureteral obstruction ureteral stone urgency urine culture Vaccine vomiting while World Health Organization [DOI] 10.7759/cureus.21730 PMC 바로가기 [Article Type] Emergency Medicine
Acute pancreatitis soon after COVID-19 vaccination A case report4500 Published on 2022-01-142022-10-30 Journal: Medicine [Category] COVID-19, [키워드] abdominal pain acute pancreatitis acute respiratory syndrome administration alcohol allergic reaction Antimicrobials Case report complications Computed tomography coronavirus COVID-19 COVID-19 mRNA Vaccination COVID-19 vaccination develop diagnosed elevated enzyme Enzymes fat first dose had no hospital Infectious disease inhibitors intravenous kidney Laboratory test mRNA vaccine occur pancrea pancreatic pandemic Patient Pfizer/BioNTech proteolytic reported serum Side effect treated Vaccine Vaccines vomiting [DOI] 10.1097/MD.0000000000028471 PMC 바로가기 [Article Type] 4500
Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19COVID-19로 입원한 성인을 대상으로 한 플리티뎁신의 전임상 및 무작위 1상 연구Clinical Trial Published on 2022-01-102022-09-10 Journal: Life Science Alliance [Category] COVID19(2023년), SARS, 변종, 비임상, 신약개발, 임상, [키워드] adults hospitalized adverse event adverse events affecting baseline breath Concentration conducted Consent diarrhea died dose elongation factor End points eukaryotic translation grade 3 hospital hospitalized patient host protein hypersensitivity inhibit initiated intensive care intensive care support invasive ventilation log lung Mortality nausea once daily one patient Open-label Patient patients with COVID-19 peptide Phase I plasma Plitidepsin Preclinical preclinical studies Randomized required respiratory Respiratory Support safety profile SARS-COV-2 infection SARS-CoV-2 replication SARS-CoV-2 variant Spanish Support Treatment Viral Viral load viral load reduction vomiting with COVID-19 [DOI] 10.26508/lsa.202101200 PMC 바로가기 [Article Type] Clinical Trial
Safety and clinical outcomes of remdesivir in hospitalised COVID-19 patients: a retrospective analysis of active surveillance database입원 COVID-19 환자에서 Remdesivir의 안전 및 임상 결과 : 활발한 감시 데이터베이스의 후 향적 분석Research Article Published on 2022-01-042022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료제, [키워드] Active surveillance Administered adverse event Analysis Antibiotics cardiac disease Clinical outcome clinical status Comorbidities concomitant medications conducted COVID-19 Data analysis Data collection database diabete diabetes died Factor High-flow oxygen hospitalised hospitalised patient Hospitalised patients hypertension increased liver enzyme increased liver enzymes India liver enzymes low-flow oxygen management mechanical ventilation men Mortality mortality rate nausea nausea and vomiting non-invasive ventilation oxygen Oxygen therapy Patient patients receiving Remdesivir Result Retrospective analysis Retrospective studies Safety safety profile significantly higher significantly lower steroid Steroids Subgroup analyses subgroup analysis supplementary material treatment for COVID-19 used data vomiting with COVID-19 [DOI] 10.1186/s12879-021-07004-8 PMC 바로가기 [Article Type] Research Article
The recombinant pseudorabies virus expressing porcine deltacoronavirus spike protein is safe and effective for miceResearch Published on 2022-01-042022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] accelerate acute diarrhea antibody BHK-21 booster candidate vaccine caused CD4 CD8 Cell coronavirus country death disease economic loss effective evaluated expected expressing expression level Genetic Homologous recombination IFN-γ IL-4 Immunity immunization immunogenicity intestinal lymphocyte mice neutralizing antibody pathogenic PDCoV Peripheral blood Porcine deltacoronavirus proliferation PROTECT protective efficacy Protein reached Recombinant pseudorabies virus Result Safe specific antibody Spike protein spleen stability supplementary material T lymphocyte up-regulated Vaccine virulent virus vomiting was increased [DOI] 10.1186/s12917-021-03115-1 PMC 바로가기 [Article Type] Research
Limited Additive Diagnostic Impact of Isolated Gastrointestinal Involvement for the Triage of Children with Suspected COVID-19Article Published on 2022-01-022022-10-31 Journal: Children [Category] COVID-19, [키워드] Additive age analyzed appear Campylobacter children children with COVID-19 Combination Complete consecutive patient COVID-19 diagnosed Diagnosis diagnostic diarrhea Fever FIVE Gastrointestinal gastrointestinal involvement Gastrointestinal symptom gastrointestinal symptoms GI symptom hospital Impact Infection Involvement Isolated Limited male median Non-COVID-19 Occurrence Pathways Patient patient triage patients patients with COVID-19 presenting proportion ranged respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection Serum level specific IgG antibodies Suspected Symptom syndrome tested the patient Triage vomiting with COVID-19 [DOI] 10.3390/children9010041 PMC 바로가기 [Article Type] Article
New-Onset Primary Adrenal Insufficiency and Autoimmune Hypothyroidism in a Pediatric Patient Presenting with MIS-CArticle Published on 2022-01-012022-11-15 Journal: Hormone research in pædiatrics [Category] 진단, [키워드] ACTH Adolescent Adrenal Adrenal insufficiency Antibody titer autoantibodies Autoimmune autoimmune conditions basal baseline bradycardia causal link children Clinical course COVID-19 creatinine criteria cytokine diarrhea EKG fatigue Fever healthy hemoglobin hemorrhage Hydrocortisone Hypothyroidism Hypothyroidism. immune Inflammatory Inflammatory marker inflammatory state initial initiated insufficiency intensive care intravenous knowledge lethargy MIS-C myocarditis oligomenorrhea PCR pediatric persistent positive positive COVID-19 reported required SARS-CoV-2 IgG SARS-COV-2 infection Shock sodium stimulated subsequent Support syndrome Thyroid Thyroiditis triggering TSH undetectable unique vomiting [DOI] 10.1159/000525227 PMC 바로가기
COVID-19 diversity: A case of multisystem inflammatory syndrome in children masquerading as juvenile systemic lupus erythematosusArticle Published on 2022-01-012022-11-15 Journal: International journal of immunopathology and pharm [Category] SARS, 진단, [키워드] acute respiratory syndrome antibody arthralgia autoantibody bicytopenia Chest children consolidation Coronavirus-2 COVID-19 DNA ECHO Evolution exhibited Features Fever general condition heterogeneity HRCT IgG Immunosuppressive medication Infection Inflammatory initial Kawasaki disease manifestation Manifestations MIS-C multisystem inflammatory syndrome in children oedema persistence positive provide raised Rash SARS-CoV-2 SARS-COV-2 infection serology SLE syndrome systemic lupus erythematosus therapy Thrombus unique university vomiting widespread [DOI] 10.1177/03946320221131981 PMC 바로가기
Glycosides for Peripheral Neuropathic Pain: A Potential Medicinal ComponentsReview Published on 2021-12-312022-10-30 Journal: Molecules [Category] COVID-19, [키워드] Adverse reactions antinociceptive component Compound disease Dizziness drug Effect effective Efficacy Epidemiology Evidence facilitate glycoside Glycosides IMPROVE induce involved ion channels Laboratory mechanism membrane membrane receptors mental health Mild natural neuropathic neuropathic pain occur oedema oxidative stress Pain Patient patients peripheral pharmacological agent plant Potential Quality of life receptor Research Sedation shown therapeutic drug transcriptional regulation treat Treatment vomiting [DOI] 10.3390/molecules27010255 PMC 바로가기 [Article Type] Review