Dynamics of antibody titers and cellular immunity among Japanese healthcare workers during the 6 months after receiving two doses of BNT162b2 mRNA vaccineBNT162b2 mRNA 백신 2회 접종 후 6개월 동안 일본 의료 종사자의 항체 역가 및 세포 면역의 역학Article Published on 2022-07-302022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] All participant All participants Analysis antibody Antibody titer Antibody titers Asymptomatic BNT162b2 BNT162b2 mRNA BNT162b2 vaccine Breakthrough infection breakthrough infections Cellular immune response cellular immune responses cellular immunity clinical trial collected conducted COVID-19 determinant determinants determine dose Dynamics elevated follow-up period healthcare healthcare worker Healthcare workers humoral IgG immune response immune responses incidence Japanese knowledge medical condition Medical conditions mRNA vaccine mRNA vaccines Nucleocapsid proteins of BNT162b2 participant Pfizer Pfizer-BioNTech positive prospective cohort study receiving SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine seroconverted serum sample serum samples study period T-cell immune response T-cell immune responses timepoint vaccination Vaccine waned were measured within 6 months [DOI] 10.1016/j.vaccine.2022.06.016 PMC 바로가기 [Article Type] Article
Six-Month Follow-Up of Immune Responses after a Rapid Mass Vaccination against SARS-CoV-2 with BNT162b2 in the District of Schwaz/AustriaSchwaz/Austria 지역에서 BNT162b2를 사용한 SARS-CoV-2에 대한 신속한 대량 백신 접종 후 면역 반응의 6개월 추적Article Published on 2022-07-272022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] age Analysis antibody Antibody Response B-cell response B.1.351 Beta BNT162b2 carried correlated COVID-19 detect District enrolment evaluate immune response immune responses Infection mass mass vaccination natural infection new SARS-CoV-2 no correlation outbreak participant participated preserved provide Rapid reduction in response robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections second dose Seropositivity Serum level serum levels specific antibodies spring study participant subject Support T cell T cell response T cell responses T-cell Response the District the SARS-CoV-2 vaccination variant waned was measured [DOI] 10.3390/v14081642 PMC 바로가기 [Article Type] Article
Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination감염 및 백신 접종 후 SARS-CoV-2 항체 결합력 반응의 역학Article Published on 2022-07-082022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Algorithm antibody Antibody avidity antibody levels Antibody Response Antibody responses avidity Cohort coronavirus COVID-19 pandemic Critical domain Epidemics estimation FIVE healthcare worker Healthcare workers IgA IgA antibodies IgA antibody IgG Including Inclusion Infection information kinetic Kinetics multiplex Multiplex assay nucleocapsid nursing home performed RBD respiratory response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection Serological assay serological assays serology severe acute respiratory syndrome Coronavirus spike subunit the SARS-CoV-2 time since infection vaccination waned while [DOI] 10.3390/v14071491 PMC 바로가기 [Article Type] Article
Comparative analysis of human immune responses following SARS-CoV-2 vaccination with BNT162b2, mRNA-1273, or Ad26.COV2.S Research Published on 2022-07-062022-10-05 Journal: NPJ Vaccines [Category] 유전자 메커니즘, [키워드] Ad26.COV2.S antibody BNT162b2 booster Comparative analysis declined delta variant domain drug elicited ELISA Emergency use authorization evaluated food human immune response humoral Humoral response IFN immune response Immunity individual initial magnitude mRNA-1273 mRNA-based vaccine Neutralization assay Observational cohort study SARS-CoV-2 spike protein SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 virus Support T cell response vaccination Vaccines variants waned wild-type strain γ ELISPOT assay [DOI] 10.1038/s41541-022-00504-x [Article Type] Research
Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trialRandomized Controlled Trial Published on 2022-07-052022-10-05 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 임상, 진단, [키워드] 1:1 active against addition age Analysis assigned B.1.1.529 baseline Community Complete COVID-19 COVID-19 symptom COVID-19 vaccination COVID-19 vaccine death diagnostic dose double-blind drugs Efficacy Endpoint expected finding follow-up period funding Health healthy Hoffmann-La Roche hospitalised household contact immune response incidence infected individuals Infectious diseases investigator Local monoclonal antibody combination mounted occurred participant patient population Placebo placebo-controlled trial post-hoc post-hoc analysis prespecified analysis prevented prevention of COVID-19 Prophylaxis proportion provided randomisation randomised Randomly receive receiving reduced Regeneron Pharmaceuticals Registered reported risk of COVID-19 risk reduction Romania RT-PCR testing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected individual Seroconversion seronegative seropositive shown single dose strain stratified subcutaneous injection susceptible symptomatic SARS-CoV-2 infection the placebo group timepoint treatment-emergent adverse event treatment-emergent adverse events uninfected unmet need USA variants waned [DOI] 10.1016/S1473-3099(22)00416-9 [Article Type] Randomized Controlled Trial
Modeling long-term impacts of the COVID-19 pandemic and oil price declines on Gulf oil economiesResearch article Published on 2022-07-012022-10-05 Journal: Economic Modelling [Category] 변종, [키워드] accelerate agreement applied COVID COVID-19 pandemic Critical Decline detrimental Economic sustainability Effect Efficiency energy Energy transition equilibrium Fiscal policy General equilibrium Government Gulf Impact implementation Kuwait Model modeling pandemic Paris potential benefits PROTECT reduce Resilience significantly subsequent targets waned weakened [DOI] 10.1016/j.econmod.2022.105849 [Article Type] Research article
COVID-19 vaccine waning and effectiveness and side-effects of boosters: a prospective community study from the ZOE COVID StudyCOVID-19 백신 약화 및 부스터의 효과 및 부작용: ZOE COVID 연구의 전향적 커뮤니티 연구Article Published on 2022-07-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Adverse reaction Adverse reactions Alpha Analysis B.1.1.7 BNT162b2 booster booster dose booster doses ChAdOx1 ChAdOx1 nCoV-19 chronic chronic disease Community community setting Comorbidities completion confounder confounders Control country COVID COVID-19 COVID-19 vaccine dose effective Effectiveness fatigue foundation group Heterologous heterologous schedule heterologous schedules homologous schedule individual Infection investigated Local local symptom Medical Research Council mRNA mRNA-1273 mRNA1273 nCoV new SARS-CoV-2 Odds ratio Older participant Participants Pfizer-BioNTech Poisson regression model positive reactogenicity receiving regimens remained reported SARS-CoV-2 SARS-CoV-2 positivity SARS-CoV-2 test second dose self-reported systemic Side-effect Side-effects Symptom systemic systemic side-effect Systemic side-effects systemic symptom tenderness test result tested those with comorbidities vaccinated individual vaccinated individuals vaccination Vaccine vaccine dose variant variants waned Wellcome Trust [DOI] 10.1016/S1473-3099(22)00146-3 PMC 바로가기 [Article Type] Article
Association of Prior BNT162b2 COVID-19 Vaccination With Symptomatic SARS-CoV-2 Infection in Children and Adolescents During Omicron PredominanceArticle Published on 2022-06-142022-11-16 Journal: JAMA [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI access adjusted adjusted odds ratio Adolescent Adults age amplification Analysis association BNT162b2 booster booster dose Case-control children conducted Control COVID-19 COVID-19 vaccine dose Effectiveness evaluate female Increasing Infection IQR median age of BNT162b2 omicron outcome pediatric Pfizer-BioNTech platform receive SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 testing symptomatic symptomatic infection symptomatic SARS-CoV-2 infection Testing the SARS-CoV-2 Trial vaccination Vaccine variant variants waned was reduced was used white [DOI] 10.1001/jama.2022.7493 PMC 바로가기
Waning effectiveness of the third dose of the BNT162b2 mRNA COVID-19 vaccineBNT162b2 mRNA 코로나19 백신 3차 접종 효과 약화Article Published on 2022-06-092022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, [키워드] administration assist BNT162b2 BNT162b2 mRNA BNT162b2 vaccine booster Case-control Coronavirus disease 2019 COVID-19 vaccine decrease dose doses Effectiveness FIVE Infection information omicron Omicron variant outcome PCR test PCR tests performed Retrospective study significantly subject vaccination Vaccine variant waned [DOI] 10.1038/s41467-022-30884-6 PMC 바로가기 [Article Type] Article
Waning COVID-19 Vaccine Effectiveness for BNT162b2 and CoronaVac in Malaysia: An Observational StudyObservational Study Published on 2022-06-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI BNT162b2 confirmed COVID-19 case CoronaVac COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccines COVID-19-related death death declined Effectiveness groups ICU admission Logistic regression Malaysia National outcomes remained SARS-CoV-2 vaccination Vaccine Vaccines waned waning [DOI] 10.1016/j.ijid.2022.03.028 PMC 바로가기 [Article Type] Observational Study